"Misonidazole" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A nitroimidazole that sensitizes normally radio-resistant hypoxic cells to radiation. It may also be directly cytotoxic to hypoxic cells and has been proposed as an antineoplastic.
| Descriptor ID |
D008920
|
| MeSH Number(s) |
D02.640.672.530 D03.383.129.308.658.530
|
| Concept/Terms |
Misonidazole- Misonidazole
- alpha-(Methoxymethyl)-2-nitro-1H-imidazole-1-ethanol
Ro 07-0582- Ro 07-0582
- Ro 07 0582
- Ro 070582
- Ro 7-0582
- Ro 7 0582
- Ro 70582
|
Below are MeSH descriptors whose meaning is more general than "Misonidazole".
Below are MeSH descriptors whose meaning is more specific than "Misonidazole".
This graph shows the total number of publications written about "Misonidazole" by people in this website by year, and whether "Misonidazole" was a major or minor topic of these publications.
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Below are the most recent publications written about "Misonidazole" by people in Profiles.
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The end of the hypoxic EPOch. Int J Radiat Oncol Biol Phys. 2015 Apr 01; 91(5):895-7.
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Development of F-18-labeled fluoroerythronitroimidazole as a PET agent for imaging tumor hypoxia. Radiology. 1995 Mar; 194(3):795-800.
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The treatment of hepatic metastases from colorectal cancer with radiation therapy alone or combined with chemotherapy or misonidazole. Cancer Treat Rev. 1989 Dec; 16(4):213-9.
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Misonidazole and hemibody irradiation in the palliation of widespread metastases. Final report of an RTOG study. Am J Clin Oncol. 1985 Aug; 8(4):293-7.
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The effect of breathing 100% oxygen on lung response to radiation in mice. Radiother Oncol. 1985 Feb; 3(2):177-9.
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Late effects of irradiation in mouse jejunum. Int J Radiat Biol Relat Stud Phys Chem Med. 1984 Aug; 46(2):125-34.
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Pharmacokinetics and toxicology of continuously infused nitroimidazoles. Int J Radiat Oncol Biol Phys. 1984 Aug; 10(8):1311-4.
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Misonidazole neurotoxicity in mice decreased by administration with pyridoxine. Int J Radiat Oncol Biol Phys. 1983 Oct; 9(10):1513-9.
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Regional [14C]misonidazole distribution in experimental RT-9 brain tumors. Cancer Res. 1983 Aug; 43(8):3800-7.
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Initial pharmacology and toxicology of intravenous desmethylmisonidazole. Int J Radiat Oncol Biol Phys. 1982 Mar-Apr; 8(3-4):371-5.