"alpha-Thalassemia" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A disorder characterized by reduced synthesis of the alpha chains of hemoglobin. The severity of this condition can vary from mild anemia to death, depending on the number of genes deleted.
| Descriptor ID |
D017085
|
| MeSH Number(s) |
C15.378.071.141.150.875.100 C15.378.420.826.100 C16.320.070.875.100 C16.320.365.826.100
|
| Concept/Terms |
alpha-Thalassemia- alpha-Thalassemia
- alpha-Thalassemias
- Alpha Thalassemia
- Thalassemia, Alpha
- Thalassemia-alpha
- Thalassemia alpha
- A-Thalassemia
- Hemoglobin H Disease
- Disease, Hemoglobin H
|
Below are MeSH descriptors whose meaning is more general than "alpha-Thalassemia".
Below are MeSH descriptors whose meaning is more specific than "alpha-Thalassemia".
This graph shows the total number of publications written about "alpha-Thalassemia" by people in this website by year, and whether "alpha-Thalassemia" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 2 | 0 | 2 |
| 2008 | 1 | 0 | 1 |
| 2009 | 1 | 0 | 1 |
| 2010 | 1 | 0 | 1 |
| 2012 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2025 | 0 | 1 | 1 |
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Below are the most recent publications written about "alpha-Thalassemia" by people in Profiles.
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ATRX silences Cartpt expression in osteoblastic cells during skeletal development. J Clin Invest. 2025 Jan 02; 135(1).
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Context matters - Daxx and Atrx are not robust tumor suppressors in the murine endocrine pancreas. Dis Model Mech. 2022 08 01; 15(8).
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Comparisons of oxygen gradient ektacytometry parameters between sickle cell patients with or without a-thalassaemia. Br J Haematol. 2021 11; 195(4):629-633.
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Genetic modifiers of severity in sickle cell disease. Clin Hemorheol Microcirc. 2018; 68(2-3):147-164.
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Genetic modifiers of sickle cell anemia in the BABY HUG cohort: influence on laboratory and clinical phenotypes. Am J Hematol. 2013 Jul; 88(7):571-6.
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Pain in thalassaemia: the effects of age on pain frequency and severity. Br J Haematol. 2013 Mar; 160(5):680-7.
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Haemoglobinopathies and the clinical epidemiology of malaria: a systematic review and meta-analysis. Lancet Infect Dis. 2012 Jun; 12(6):457-68.
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Alpha-thalassemia is associated with a decreased occurrence and a delayed age-at-onset of albuminuria in sickle cell anemia patients. Blood Cells Mol Dis. 2010 Aug 15; 45(2):154-8.
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Homozygous alpha-thalassemia treated with intrauterine transfusions and unrelated donor hematopoietic cell transplantation. J Pediatr. 2009 May; 154(5):766-8.
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Elevated middle cerebral artery peak systolic velocity without fetal anemia in a case of homozygous alpha-thalassemia-1. Prenat Diagn. 2008 Jan; 28(1):72-4.