"Chlorthalidone" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A benzenesulfonamide-phthalimidine that tautomerizes to a BENZOPHENONES form. It is considered a thiazide-like diuretic.
| Descriptor ID |
D002752
|
| MeSH Number(s) |
D02.065.884.365 D02.455.426.559.389.134.500 D02.478.600.500 D02.522.223.500 D02.886.590.700.365 D03.633.100.513.750.500
|
| Concept/Terms |
Chlorthalidone- Chlorthalidone
- Chlorphthalidolone
- Phthalamudine
- Oxodoline
- Chlortalidone
|
Below are MeSH descriptors whose meaning is more general than "Chlorthalidone".
Below are MeSH descriptors whose meaning is more specific than "Chlorthalidone".
This graph shows the total number of publications written about "Chlorthalidone" by people in this website by year, and whether "Chlorthalidone" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 1 | 0 | 1 |
| 2005 | 0 | 2 | 2 |
| 2006 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2012 | 1 | 2 | 3 |
| 2013 | 0 | 1 | 1 |
| 2014 | 1 | 2 | 3 |
| 2017 | 1 | 1 | 2 |
| 2018 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Chlorthalidone" by people in Profiles.
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Revisiting diuretic choice in chronic kidney disease. Curr Opin Nephrol Hypertens. 2022 09 01; 31(5):406-413.
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Chlorthalidone in Advanced Chronic Kidney Disease - Have We Missed a Trick? N Engl J Med. 2021 12 30; 385(27):2574-2575.
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Genome Wide Analysis Approach Suggests Chromosome 2 Locus to be Associated with Thiazide and Thiazide Like-Diuretics Blood Pressure Response. Sci Rep. 2019 11 21; 9(1):17323.
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Genome Wide Association Study Identifies the HMGCS2 Locus to be Associated With Chlorthalidone Induced Glucose Increase in Hypertensive Patients. J Am Heart Assoc. 2018 03 09; 7(6).
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Whole Transcriptome Sequencing Analyses Reveal Molecular Markers of Blood Pressure Response to Thiazide Diuretics. Sci Rep. 2017 11 22; 7(1):16068.
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Genome-Wide Prioritization and Transcriptomics Reveal Novel Signatures Associated With Thiazide Diuretics Blood Pressure Response. Circ Cardiovasc Genet. 2017 Jan; 10(1).
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Characteristics and long-term follow-up of participants with peripheral arterial disease during ALLHAT. J Gen Intern Med. 2014 Nov; 29(11):1475-83.
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Pharmacogenetic effects of 'candidate gene complexes' on stroke in the GenHAT study. Pharmacogenet Genomics. 2014 Nov; 24(11):556-63.
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Stroke outcomes among participants randomized to chlorthalidone, amlodipine or lisinopril in ALLHAT. J Am Soc Hypertens. 2014 Nov; 8(11):808-19.
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Mortality and morbidity during and after Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial: results by sex. Hypertension. 2013 May; 61(5):977-86.