Dentinogenesis Imperfecta
"Dentinogenesis Imperfecta" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An autosomal dominant disorder of tooth development characterized by opalescent dentin resulting in discoloration of the teeth. The dentin develops poorly with low mineral content while the pulp canal is obliterated.
Descriptor ID |
D003811
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MeSH Number(s) |
C07.650.800.270 C07.793.700.270 C16.131.850.800.270
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Concept/Terms |
Opalescent Dentin- Opalescent Dentin
- Dentin, Opalescent
- Dentinogenesis Imperfecta 1
- Imperfecta 1, Dentinogenesis
- Capdepont Teeth
- Teeth, Capdepont
- Dentinogenesis Imperfecta, Shields Type II
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Below are MeSH descriptors whose meaning is more general than "Dentinogenesis Imperfecta".
Below are MeSH descriptors whose meaning is more specific than "Dentinogenesis Imperfecta".
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Below are the most recent publications written about "Dentinogenesis Imperfecta" by people in Profiles.
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Transcriptional repression of the Dspp gene leads to dentinogenesis imperfecta phenotype in Col1a1-Trps1 transgenic mice. J Bone Miner Res. 2012 Aug; 27(8):1735-45.
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The carboxyl-terminal domain of phosphophoryn contains unique extended triplet amino acid repeat sequences forming ordered carboxyl-phosphate interaction ridges that may be essential in the biomineralization process. J Biol Chem. 1996 Dec 20; 271(51):32869-73.