"Poloxamer" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A nonionic polyoxyethylene-polyoxypropylene block co-polymer with the general formula HO(C2H4O)a(-C3H6O)b(C2H4O)aH. It is available in different grades which vary from liquids to solids. It is used as an emulsifying agent, solubilizing agent, surfactant, and wetting agent for antibiotics. Poloxamer is also used in ointment and suppository bases and as a tablet binder or coater. (Martindale The Extra Pharmacopoeia, 31st ed)
| Descriptor ID |
D020442
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| MeSH Number(s) |
D02.033.455.250.700.682 D05.750.741.667 D25.720.741.667 J01.637.051.720.741.667
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Poloxamer".
Below are MeSH descriptors whose meaning is more specific than "Poloxamer".
This graph shows the total number of publications written about "Poloxamer" by people in this website by year, and whether "Poloxamer" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 2 | 0 | 2 |
| 2005 | 1 | 0 | 1 |
| 2006 | 2 | 0 | 2 |
| 2007 | 1 | 0 | 1 |
| 2014 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
| 2020 | 0 | 1 | 1 |
| 2022 | 0 | 2 | 2 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Poloxamer" by people in Profiles.
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Development of Novel 3D Spheroids for Discrete Subaortic Stenosis. Cardiovasc Eng Technol. 2024 12; 15(6):704-715.
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Poloxamer 407 Induces Hypertriglyceridemia but Decreases Atherosclerosis in Ldlr-/- Mice. Cells. 2022 05 30; 11(11).
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In situ gelling system for sustained intraarticular delivery of bupivacaine and ketorolac in sheep. Eur J Pharm Biopharm. 2022 May; 174:35-46.
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Delivery of thymoquinone through hyaluronic acid-decorated mixed Pluronic? nanoparticles to attenuate angiogenesis and metastasis of triple-negative breast cancer. J Control Release. 2020 06 10; 322:357-374.
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Injectable thermosensitive gelling delivery system for the sustained release of lidocaine. Ther Deliv. 2016 06; 7(6):359-68.
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Potential avoidance of adverse analgesic effects using a biologically "smart" hydrogel capable of controlled bupivacaine release. J Pharm Sci. 2014 Nov; 103(11):3724-3732.
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Thermally responsive nanoparticle-encapsulated curcumin and its combination with mild hyperthermia for enhanced cancer cell destruction. Acta Biomater. 2014 Feb; 10(2):831-42.
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Synthesis and characterization of thermally responsive Pluronic F127-chitosan nanocapsules for controlled release and intracellular delivery of small molecules. ACS Nano. 2010 Nov 23; 4(11):6747-59.
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Neuroprotective effect of the surfactant poloxamer 188 in a model of intracranial hemorrhage in rats. J Neurosurg. 2007 Jan; 106(1 Suppl):36-40.
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Temporary coronary artery occlusion during off-pump coronary artery bypass grafting with the new poloxamer P407 does not cause endothelial dysfunction in epicardial coronary arteries. J Thorac Cardiovasc Surg. 2006 Nov; 132(5):1144-9.