Bone Morphogenetic Protein Receptors, Type I
"Bone Morphogenetic Protein Receptors, Type I" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subtype of bone morphogenetic protein receptors with high affinity for BONE MORPHOGENETIC PROTEINS. They can interact with and undergo PHOSPHORYLATION by BONE MORPHOGENETIC PROTEIN RECEPTORS, TYPE II. They signal primarily through RECEPTOR-REGULATED SMAD PROTEINS.
| Descriptor ID |
D052005
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| MeSH Number(s) |
D08.811.913.696.620.682.700.109.500 D12.776.543.750.750.400.049.500
|
| Concept/Terms |
Bone Morphogenetic Protein Receptors, Type I- Bone Morphogenetic Protein Receptors, Type I
- BMPR-I Receptors
- BMPR I Receptors
- Type I Bone Morphogenetic Protein Receptors
- BMP Type I Receptor
- Bone Morphogenetic Protein Receptor Type I
Bone Morphogenetic Protein Receptor, Type IA- Bone Morphogenetic Protein Receptor, Type IA
- Type IA Bone Morphogenetic Protein Receptor
- BMPR-IA Receptor
- BMPR IA Receptor
- Activin Receptor-Like Kinase 3
- Activin Receptor Like Kinase 3
- BMP Type IA Receptor
Bone Morphogenetic Protein Receptor, Type IB- Bone Morphogenetic Protein Receptor, Type IB
- Type IB Bone Morphogenetic Protein Receptor
- BMPR-IB Receptor
- BMPR IB Receptor
- Serine-Threonine Protein Kinase Receptor R6
- Serine Threonine Protein Kinase Receptor R6
- Activin Receptor-Like Kinase 6
- Activin Receptor Like Kinase 6
- BMP Type IB Receptor
|
Below are MeSH descriptors whose meaning is more general than "Bone Morphogenetic Protein Receptors, Type I".
Below are MeSH descriptors whose meaning is more specific than "Bone Morphogenetic Protein Receptors, Type I".
This graph shows the total number of publications written about "Bone Morphogenetic Protein Receptors, Type I" by people in this website by year, and whether "Bone Morphogenetic Protein Receptors, Type I" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 0 | 1 | 1 |
| 2007 | 0 | 2 | 2 |
| 2008 | 2 | 1 | 3 |
| 2009 | 1 | 0 | 1 |
| 2010 | 1 | 1 | 2 |
| 2011 | 0 | 2 | 2 |
| 2012 | 0 | 1 | 1 |
| 2013 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2018 | 1 | 1 | 2 |
| 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Bone Morphogenetic Protein Receptors, Type I" by people in Profiles.
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Phenotypic Differences in Juvenile Polyposis Syndrome With or Without a Disease-causing SMAD4/BMPR1A Variant. Cancer Prev Res (Phila). 2021 02; 14(2):215-222.
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Cytokine sensitivity screening highlights BMP4 pathway signaling as a therapeutic opportunity in ER+ breast cancer. FASEB J. 2019 02; 33(2):1644-1657.
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Pharmacological induction of hypoxia-inducible transcription factor ARNT attenuates chronic kidney failure. J Clin Invest. 2018 07 02; 128(7):3053-3070.
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BMPRIA is required for osteogenic differentiation and RANKL expression in adult bone marrow mesenchymal stromal cells. Sci Rep. 2018 05 31; 8(1):8475.
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A novel homozygous variant in BMPR1B underlies acromesomelic dysplasia Hunter-Thompson type. Ann Hum Genet. 2018 05; 82(3):129-134.
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Uterine ALK3 is essential during the window of implantation. Proc Natl Acad Sci U S A. 2016 Jan 19; 113(3):E387-95.
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A role for BMP-induced homeobox gene MIXL1 in acute myelogenous leukemia and identification of type I BMP receptor as a potential target for therapy. Oncotarget. 2014 Dec 30; 5(24):12675-93.
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Development of an ALK2-biased BMP type I receptor kinase inhibitor. ACS Chem Biol. 2013; 8(6):1291-302.
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LRP1-dependent endocytic mechanism governs the signaling output of the bmp system in endothelial cells and in angiogenesis. Circ Res. 2012 Aug 17; 111(5):564-74.
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Activin-like kinase 3 is important for kidney regeneration and reversal of fibrosis. Nat Med. 2012 Feb 05; 18(3):396-404.