Tosylphenylalanyl Chloromethyl Ketone
"Tosylphenylalanyl Chloromethyl Ketone" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An inhibitor of Serine Endopeptidases. Acts as alkylating agent and is known to interfere with the translation process.
| Descriptor ID |
D014108
|
| MeSH Number(s) |
D02.455.426.559.389.832.710 D02.886.590.887.660 D12.125.065.930
|
| Concept/Terms |
Tosylphenylalanyl Chloromethyl Ketone- Tosylphenylalanyl Chloromethyl Ketone
- Chloromethyl Ketone, Tosylphenylalanyl
- Ketone, Tosylphenylalanyl Chloromethyl
- Tosylphenylalanyl Chloromethane
- Chloromethane, Tosylphenylalanyl
- TPCK
- Chlorophenyltosylamidobutanone
|
Below are MeSH descriptors whose meaning is more general than "Tosylphenylalanyl Chloromethyl Ketone".
Below are MeSH descriptors whose meaning is more specific than "Tosylphenylalanyl Chloromethyl Ketone".
This graph shows the total number of publications written about "Tosylphenylalanyl Chloromethyl Ketone" by people in this website by year, and whether "Tosylphenylalanyl Chloromethyl Ketone" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 2 | 2 |
| 1995 | 0 | 2 | 2 |
| 1999 | 0 | 1 | 1 |
| 2000 | 0 | 1 | 1 |
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Below are the most recent publications written about "Tosylphenylalanyl Chloromethyl Ketone" by people in Profiles.
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Apaf-1 oligomerizes into biologically active approximately 700-kDa and inactive approximately 1.4-MDa apoptosome complexes. J Biol Chem. 2000 Mar 03; 275(9):6067-70.
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Overexpression of urokinase-type plasminogen activator in pancreatic adenocarcinoma is regulated by constitutively activated RelA. Oncogene. 1999 Aug 12; 18(32):4554-63.
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Dependence and reversal of nitric oxide production on NF-kappa B in silica and lipopolysaccharide-induced macrophages. Biochem Biophys Res Commun. 1995 Sep 25; 214(3):839-46.
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Essential role of NF-kappa B activation in silica-induced inflammatory mediator production in macrophages. Biochem Biophys Res Commun. 1995 Sep 25; 214(3):985-92.
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Enhanced I kappa B alpha degradation is responsible for constitutive NF-kappa B activity in mature murine B-cell lines. Mol Cell Biol. 1994 May; 14(5):3276-82.
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Autoregulation of I kappa B alpha activity. Proc Natl Acad Sci U S A. 1994 Jan 04; 91(1):28-32.