Myelinolysis, Central Pontine
"Myelinolysis, Central Pontine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A demyelinating condition affecting the PONS and characterized clinically by an acute progressive QUADRIPLEGIA; DYSARTHRIA; DYSPHAGIA; and alterations of consciousness. Pathologic features include prominent demyelination in the central PONS with sparing of axons and neurons. This condition is usually associated with systemic disorders such as HYPONATREMIA; chronic ALCOHOLISM; LIVER FAILURE; severe BURNS; malignant NEOPLASMS; hemorrhagic PANCREATITIS; HEMODIALYSIS; and SEPSIS. The rapid medical correction of hyponatremia has been cited as a cause of this condition. (From Adams et al., Principles of Neurology, 6th ed, pp1125-6)
Descriptor ID |
D017590
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MeSH Number(s) |
C10.228.140.163.560 C10.314.500 C18.452.132.560
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Concept/Terms |
Myelinolysis, Central Pontine- Myelinolysis, Central Pontine
- Pontine Myelinolysis, Central
- Myelinoclasis, Central Pontine
- Central Pontine Myelinoclasis
- Central Pontine Myelinolysis
Extrapontine Myelinolysis- Extrapontine Myelinolysis
- Extrapontine Myelinolyses
- Myelinolyses, Extrapontine
- Myelinolysis, Extrapontine
- Extrapontine Myelinoclasis
- Extrapontine Myelinoclases
- Myelinoclases, Extrapontine
- Myelinoclasis, Extrapontine
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Below are MeSH descriptors whose meaning is more general than "Myelinolysis, Central Pontine".
Below are MeSH descriptors whose meaning is more specific than "Myelinolysis, Central Pontine".
This graph shows the total number of publications written about "Myelinolysis, Central Pontine" by people in this website by year, and whether "Myelinolysis, Central Pontine" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2000 | 1 | 0 | 1 |
2002 | 1 | 0 | 1 |
2017 | 1 | 0 | 1 |
2022 | 1 | 0 | 1 |
2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "Myelinolysis, Central Pontine" by people in Profiles.
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A rare presentation of central pontine myelinolysis secondary to hyperglycaemia. BMC Endocr Disord. 2023 May 10; 23(1):106.
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Central and Extrapontine Myelinolysis in the Setting of Hyperglycemia. Prim Care Companion CNS Disord. 2022 10 11; 24(5).
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Osmotic Demyelination Unrelated to Hyponatremia. Am J Kidney Dis. 2018 03; 71(3):436-440.
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Central pontine myelinolysis: a metabolic disorder of myelin. J Neuropsychiatry Clin Neurosci. 2011; 23(4):369-74.
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Benign course of central pontine myelinolysis in a patient with anorexia nervosa. Pediatr Neurol. 2002 Aug; 27(2):132-5.
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Methylphenidate treatment of neuropsychiatric symptoms of central and extrapontine myelinolysis. J Stud Alcohol. 2000 Sep; 61(5):657-60.