"Acarbose" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An inhibitor of ALPHA-GLUCOSIDASES that retards the digestion and absorption of DIETARY CARBOHYDRATES in the SMALL INTESTINE.
| Descriptor ID |
D020909
|
| MeSH Number(s) |
D09.698.629.802.100
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Acarbose".
Below are MeSH descriptors whose meaning is more specific than "Acarbose".
This graph shows the total number of publications written about "Acarbose" by people in this website by year, and whether "Acarbose" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 0 | 1 | 1 |
| 2013 | 1 | 0 | 1 |
| 2017 | 0 | 1 | 1 |
| 2020 | 1 | 0 | 1 |
| 2022 | 0 | 1 | 1 |
| 2023 | 1 | 0 | 1 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Acarbose" by people in Profiles.
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Pyrano[2,3-b]chromone derivatives as novel dual inhibitors of a-glucosidase and a-amylase: Design, synthesis, biological evaluation, and in silico studies. Bioorg Chem. 2024 04; 145:107207.
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Discovery of novel 4,5-diphenyl-imidazol-a-aminophosphonate hybrids as promising anti-diabetic agents: Design, synthesis, in vitro, and in silico enzymatic studies. Bioorg Chem. 2023 12; 141:106846.
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Molecular dynamics simulation and pharmacokinetics studies of ombuin and quercetin against human pancreatic a-amylase. J Biomol Struct Dyn. 2023 12; 41(20):10388-10395.
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Diabetes medications as potential calorie restriction mimetics-a focus on the alpha-glucosidase inhibitor acarbose. Geroscience. 2021 06; 43(3):1123-1133.
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Cardiac response to enzyme replacement therapy in infantile Pompe disease with severe hypertrophic cardiomyopathy. Echocardiography. 2017 Apr; 34(4):621-624.
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Acarbose, 17-a-estradiol, and nordihydroguaiaretic acid extend mouse lifespan preferentially in males. Aging Cell. 2014 Apr; 13(2):273-82.
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Contribution of mucosal maltase-glucoamylase activities to mouse small intestinal starch alpha-glucogenesis. J Nutr. 2007 Jul; 137(7):1725-33.