"Poly I-C" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Interferon inducer consisting of a synthetic, mismatched double-stranded RNA. The polymer is made of one strand each of polyinosinic acid and polycytidylic acid.
| Descriptor ID |
D011070
|
| MeSH Number(s) |
D13.695.578.550.560.600 D13.695.578.550.650.600
|
| Concept/Terms |
Poly I-C- Poly I-C
- Poly I C
- Poly(I-C)
- Polyriboinosinic-Polyribocytidylic Acid
- Polyriboinosinic Polyribocytidylic Acid
- Polyribose Inosin-Cytidil
- Inosin-Cytidil, Polyribose
- Polyribose Inosin Cytidil
- Poly(rI).Poly(rC)
- Polyinosinic-Polycytidylic Acid
- Polyinosinic Polycytidylic Acid
- Polyinosinic-Polycytidylic Acid (High MW)
|
Below are MeSH descriptors whose meaning is more general than "Poly I-C".
Below are MeSH descriptors whose meaning is more specific than "Poly I-C".
This graph shows the total number of publications written about "Poly I-C" by people in this website by year, and whether "Poly I-C" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 1 | 0 | 1 |
| 2005 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2010 | 2 | 2 | 4 |
| 2011 | 0 | 2 | 2 |
| 2012 | 0 | 1 | 1 |
| 2015 | 1 | 1 | 2 |
| 2016 | 0 | 2 | 2 |
| 2019 | 1 | 1 | 2 |
| 2021 | 0 | 1 | 1 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Poly I-C" by people in Profiles.
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Myeloid-associated differentiation marker is associated with type 2 asthma and is upregulated by human rhinovirus infection. Front Immunol. 2023; 14:1237683.
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STAT3 Inhibits Autocrine IFN Signaling in Type I Conventional Dendritic Cells. J Immunol. 2022 10 01; 209(7):1286-1299.
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Viral model of maternal immune activation alters placental AMPK and mTORC1 signaling in rats. Placenta. 2021 09 01; 112:36-44.
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Molecular characterization, tissue distribution and functional analysis of galectin 1-like 2 in grass carp (Ctenopharyngodon idella). Fish Shellfish Immunol. 2019 Nov; 94:455-463.
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Phase I/II trial testing safety and immunogenicity of the multipeptide IMA950/poly-ICLC vaccine in newly diagnosed adult malignant astrocytoma patients. Neuro Oncol. 2019 07 11; 21(7):923-933.
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Poly(I:C) alters placental and fetal brain amino acid transport in a rat model of maternal immune activation. Am J Reprod Immunol. 2019 06; 81(6):e13115.
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Strain differences in the susceptibility to the gut-brain axis and neurobehavioural alterations induced by maternal immune activation in mice. Behav Pharmacol. 2018 04; 29(2 and 3-Spec Issue):181-198.
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In vivo stepwise immunomodulation using chitosan nanoparticles as a platform nanotechnology for cancer immunotherapy. Sci Rep. 2016 12 02; 6:38348.
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Protease-Activated Receptor 1 Enhances Poly I:C Induction of the Antiviral Response in Macrophages and Mice. J Innate Immun. 2017; 9(2):181-192.
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Metformin improves defective hematopoiesis and delays tumor formation in Fanconi anemia mice. Blood. 2016 12 15; 128(24):2774-2784.