"Kinetochores" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Large multiprotein complexes that bind the centromeres of the chromosomes to the microtubules of the mitotic spindle during metaphase in the cell cycle.
| Descriptor ID |
D018386
|
| MeSH Number(s) |
A11.284.430.106.279.345.190.160.165.500 G05.360.160.165.500
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Kinetochores".
Below are MeSH descriptors whose meaning is more specific than "Kinetochores".
This graph shows the total number of publications written about "Kinetochores" by people in this website by year, and whether "Kinetochores" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
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Below are the most recent publications written about "Kinetochores" by people in Profiles.
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PKM2 regulates chromosome segregation and mitosis progression of tumor cells. Mol Cell. 2014 Jan 09; 53(1):75-87.
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Aurora-C kinase supports mitotic progression in the absence of Aurora-B. Cell Cycle. 2009 Sep 15; 8(18):2984-94.
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Heterozygous screen in Saccharomyces cerevisiae identifies dosage-sensitive genes that affect chromosome stability. Genetics. 2008 Mar; 178(3):1193-207.
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SAC-ing mitotic errors: how the spindle assembly checkpoint (SAC) plays defense against chromosome mis-segregation. Cell Motil Cytoskeleton. 2005 Jul; 61(3):145-60.
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The A78V mutation in the Mad3-like domain of Schizosaccharomyces pombe Bub1p perturbs nuclear accumulation and kinetochore targeting of Bub1p, Bub3p, and Mad3p and spindle assembly checkpoint function. Mol Biol Cell. 2005 Jan; 16(1):385-95.
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The mitotic spindle is required for loading of the DASH complex onto the kinetochore. Genes Dev. 2002 Jan 15; 16(2):183-97.