Peptide Elongation Factor 1
"Peptide Elongation Factor 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Peptide elongation factor 1 is a multisubunit protein that is responsible for the GTP-dependent binding of aminoacyl-tRNAs to eukaryotic ribosomes. The alpha subunit (EF-1alpha) binds aminoacyl-tRNA and transfers it to the ribosome in a process linked to GTP hydrolysis. The beta and delta subunits (EF-1beta, EF-1delta) are involved in exchanging GDP for GTP. The gamma subunit (EF-1gamma) is a structural component.
| Descriptor ID |
D020648
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| MeSH Number(s) |
D08.811.277.040.330.300.100.101 D12.776.157.325.150.101 D12.776.835.700.350.101
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Peptide Elongation Factor 1".
Below are MeSH descriptors whose meaning is more specific than "Peptide Elongation Factor 1".
This graph shows the total number of publications written about "Peptide Elongation Factor 1" by people in this website by year, and whether "Peptide Elongation Factor 1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 0 | 1 | 1 |
| 2006 | 1 | 0 | 1 |
| 2014 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
| 2019 | 0 | 1 | 1 |
| 2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "Peptide Elongation Factor 1" by people in Profiles.
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eEF1A2 promotes PTEN-GSK3?-SCF complex-dependent degradation of Aurora kinase A and is inactivated in breast cancer. Sci Signal. 2024 03 05; 17(826):eadh4475.
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Translational Control in the Brain in Health and Disease. Cold Spring Harb Perspect Biol. 2019 08 01; 11(8).
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METTL13 Methylation of eEF1A Increases Translational Output to Promote Tumorigenesis. Cell. 2019 01 24; 176(3):491-504.e21.
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Single-cell gene expression analysis reveals diversity among human spermatogonia. Mol Hum Reprod. 2017 02 10; 23(2):79-90.
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mGluR5 Exerts Cell-Autonomous Influences on the Functional and Anatomical Development of Layer IV Cortical Neurons in the Mouse Primary Somatosensory Cortex. J Neurosci. 2016 08 24; 36(34):8802-14.
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Ribosomal Biogenesis and Translational Flux Inhibition by the Selective Inhibitor of Nuclear Export (SINE) XPO1 Antagonist KPT-185. PLoS One. 2015; 10(9):e0137210.
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Plasmid-based human norovirus reverse genetics system produces reporter-tagged progeny virus containing infectious genomic RNA. Proc Natl Acad Sci U S A. 2014 Sep 23; 111(38):E4043-52.
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Use of phage display to identify novel mineralocorticoid receptor-interacting proteins. Mol Endocrinol. 2014 Sep; 28(9):1571-84.
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Looking for reference genes for real-time quantitative PCR experiments in Rhodnius prolixus (Hemiptera: Reduviidae). Insect Mol Biol. 2011 Dec; 20(6):713-22.
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3'-UTR-mediated post-transcriptional regulation of cancer metastasis: beginning at the end. RNA Biol. 2011 Jul-Aug; 8(4):595-9.