Peptide Elongation Factor 1
"Peptide Elongation Factor 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Peptide elongation factor 1 is a multisubunit protein that is responsible for the GTP-dependent binding of aminoacyl-tRNAs to eukaryotic ribosomes. The alpha subunit (EF-1alpha) binds aminoacyl-tRNA and transfers it to the ribosome in a process linked to GTP hydrolysis. The beta and delta subunits (EF-1beta, EF-1delta) are involved in exchanging GDP for GTP. The gamma subunit (EF-1gamma) is a structural component.
| Descriptor ID |
D020648
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| MeSH Number(s) |
D08.811.277.040.330.300.100.101 D12.776.157.325.150.101 D12.776.835.700.350.101
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Peptide Elongation Factor 1".
Below are MeSH descriptors whose meaning is more specific than "Peptide Elongation Factor 1".
This graph shows the total number of publications written about "Peptide Elongation Factor 1" by people in this website by year, and whether "Peptide Elongation Factor 1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 1 | 0 | 1 |
| 2016 | 0 | 1 | 1 |
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Below are the most recent publications written about "Peptide Elongation Factor 1" by people in Profiles.
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mGluR5 Exerts Cell-Autonomous Influences on the Functional and Anatomical Development of Layer IV Cortical Neurons in the Mouse Primary Somatosensory Cortex. J Neurosci. 2016 08 24; 36(34):8802-14.
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Medulloblastoma outcome is adversely associated with overexpression of EEF1D, RPL30, and RPS20 on the long arm of chromosome 8. BMC Cancer. 2006 Sep 12; 6:223.
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Regulation of elongation factor-1alpha expression by growth factors and anti-receptor blocking antibodies. J Biol Chem. 2001 Feb 23; 276(8):5636-42.