"Xanthine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A purine base found in most body tissues and fluids, certain plants, and some urinary calculi. It is an intermediate in the degradation of adenosine monophosphate to uric acid, being formed by oxidation of hypoxanthine. The methylated xanthine compounds caffeine, theobromine, and theophylline and their derivatives are used in medicine for their bronchodilator effects. (Dorland, 28th ed)
| Descriptor ID |
D019820
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| MeSH Number(s) |
D03.132.960.938 D03.633.100.759.758.824.938
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Xanthine".
Below are MeSH descriptors whose meaning is more specific than "Xanthine".
This graph shows the total number of publications written about "Xanthine" by people in this website by year, and whether "Xanthine" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 |
| 1995 | 0 | 1 | 1 |
| 2001 | 1 | 0 | 1 |
| 2008 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2017 | 0 | 1 | 1 |
| 2023 | 0 | 2 | 2 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Xanthine" by people in Profiles.
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Enterococcus faecalis-derived adenine enhances enterohaemorrhagic Escherichia coli Type 3 Secretion System-dependent virulence. Nat Microbiol. 2024 Sep; 9(9):2448-2461.
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Investigation of the Inhibition Mechanism of Xanthine Oxidoreductase by Oxipurinol: A Computational Study. J Chem Inf Model. 2023 07 10; 63(13):4190-4206.
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Xanthine-induced deficits in hippocampal behavior and abnormal expression of hemoglobin genes. Behav Brain Res. 2023 07 09; 449:114476.
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Global and targeted serum metabolic profiling of colorectal cancer progression. Cancer. 2017 Oct 15; 123(20):4066-4074.
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Potential contribution of oxidative stress and inflammation to anxiety and hypertension. Brain Res. 2011 Aug 02; 1404:63-71.
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Oxidative stress: a potential recipe for anxiety, hypertension and insulin resistance. Brain Res. 2010 Nov 04; 1359:178-85.
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Superoxide-induced potentiation in the hippocampus requires activation of ryanodine receptor type 3 and ERK. J Neurophysiol. 2008 Mar; 99(3):1565-71.
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Interstitial brain adenosine and xanthine increase during jugular venous oxygen desaturations in humans after traumatic brain injury. Crit Care Med. 2001 Feb; 29(2):399-404.
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Functional and structural interactions of the Rab5 D136N mutant with xanthine nucleotides. Biochem Biophys Res Commun. 1995 Oct 04; 215(1):241-9.
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Free oxygen radicals contribute to platelet aggregation and cyclic flow variations in stenosed and endothelium-injured canine coronary arteries. J Am Coll Cardiol. 1994 Dec; 24(7):1749-56.