"Cord Factors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Toxic glycolipids composed of trehalose dimycolate derivatives. They are produced by MYCOBACTERIUM TUBERCULOSIS and other species of MYCOBACTERIUM. They induce cellular dysfunction in animals.
| Descriptor ID |
D003311
|
| MeSH Number(s) |
D10.390.240 D23.946.123.208
|
| Concept/Terms |
Cord Factors- Cord Factors
- Factors, Cord
- Trehalose Dimycolates
- Dimycolates, Trehalose
- Cord Factor
- Factor, Cord
|
Below are MeSH descriptors whose meaning is more general than "Cord Factors".
Below are MeSH descriptors whose meaning is more specific than "Cord Factors".
This graph shows the total number of publications written about "Cord Factors" by people in this website by year, and whether "Cord Factors" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2013 | 1 | 0 | 1 |
| 2014 | 2 | 0 | 2 |
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Below are the most recent publications written about "Cord Factors" by people in Profiles.
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C-type lectin receptor dectin-3 mediates trehalose 6,6'-dimycolate (TDM)-induced Mincle expression through CARD9/Bcl10/MALT1-dependent nuclear factor (NF)-?B activation. J Biol Chem. 2014 Oct 24; 289(43):30052-62.
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A hydrolase of trehalose dimycolate induces nutrient influx and stress sensitivity to balance intracellular growth of Mycobacterium tuberculosis. Cell Host Microbe. 2014 Feb 12; 15(2):153-63.
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Cord factor and peptidoglycan recapitulate the Th17-promoting adjuvant activity of mycobacteria through mincle/CARD9 signaling and the inflammasome. J Immunol. 2013 Jun 01; 190(11):5722-30.
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Certain surfactants show promise in the therapy of pulmonary tuberculosis. In Vivo. 2010 Sep-Oct; 24(5):687-94.