Hemoglobinuria, Paroxysmal
"Hemoglobinuria, Paroxysmal" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A condition characterized by the recurrence of HEMOGLOBINURIA caused by intravascular HEMOLYSIS. In cases occurring upon cold exposure (paroxysmal cold hemoglobinuria), usually after infections, there is a circulating antibody which is also a cold hemolysin. In cases occurring during or after sleep (paroxysmal nocturnal hemoglobinuria), the clonal hematopoietic stem cells exhibit a global deficiency of cell membrane proteins.
Descriptor ID |
D006457
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MeSH Number(s) |
C15.378.071.141.560 C15.378.190.625.460
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Concept/Terms |
Paroxysmal Cold Hemoglobinuria- Paroxysmal Cold Hemoglobinuria
- Hemoglobinuria, Paroxysmal Cold
- Paroxysmal Hemoglobinuria, Cold
- Cold Paroxysmal Hemoglobinuria
- Hemoglobinuria, Cold Paroxysmal
Paroxysmal Nocturnal Hemoglobinuria- Paroxysmal Nocturnal Hemoglobinuria
- Hemoglobinuria, Paroxysmal Nocturnal
- Marchiafava-Micheli Syndrome
- Marchiafava Micheli Syndrome
- Syndrome, Marchiafava-Micheli
- Paroxysmal Hemoglobinuria, Nocturnal
- Hemoglobinuria, Nocturnal Paroxysmal
- Nocturnal Paroxysmal Hemoglobinuria
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Below are MeSH descriptors whose meaning is more general than "Hemoglobinuria, Paroxysmal".
Below are MeSH descriptors whose meaning is more specific than "Hemoglobinuria, Paroxysmal".
This graph shows the total number of publications written about "Hemoglobinuria, Paroxysmal" by people in this website by year, and whether "Hemoglobinuria, Paroxysmal" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2008 | 2 | 0 | 2 |
2009 | 1 | 0 | 1 |
2011 | 1 | 0 | 1 |
2012 | 1 | 0 | 1 |
2014 | 0 | 1 | 1 |
2015 | 0 | 1 | 1 |
2016 | 2 | 0 | 2 |
2017 | 1 | 0 | 1 |
2018 | 1 | 0 | 1 |
2019 | 2 | 1 | 3 |
2020 | 1 | 0 | 1 |
2021 | 1 | 0 | 1 |
2022 | 2 | 0 | 2 |
2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Hemoglobinuria, Paroxysmal" by people in Profiles.
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Absence of PNH-clones in DDX41mutant-GPS aids in their distinction from acquired BM failure syndromes. Leuk Res. 2024 Oct; 145:107561.
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Detection of PNH Clones can Aid in the Distinction of Aplastic Anemia vs Inherited BM Failure Syndromes: A Single Center Experience and Review of the Literature. Clin Lymphoma Myeloma Leuk. 2024 Oct; 24(10):732-735.
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COVID-19 vaccination antibody responses in patients with aplastic anaemia and paroxysmal nocturnal haemoglobinuria. Lancet Haematol. 2022 08; 9(8):e553-e556.
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Validation of a single tube 3-colour immature red blood cell screening assay for the detection and enumeration of small, medium and large paroxysmal nocturnal haemoglobinuria clones by flow cytometry. Int J Lab Hematol. 2022 Oct; 44(5):868-874.
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The incidence and prevalence of patients with paroxysmal nocturnal haemoglobinuria and aplastic anaemia PNH syndrome: A retrospective analysis of the UK's population-based haematological malignancy research network 2004-2018. Eur J Haematol. 2021 Aug; 107(2):211-218.
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Presentation clinical, haematological and immunophenotypic features of 1081 patients with GPI-deficient (paroxysmal nocturnal haemoglobinuria) cells detected by flow cytometry. Br J Haematol. 2020 06; 189(5):954-966.
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Ontogeny of human B1 cells. Int J Hematol. 2020 May; 111(5):628-633.
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CD71 improves delineation of PNH type III, PNH type II, and normal immature RBCS in patients with paroxysmal nocturnal hemoglobinuria. Cytometry B Clin Cytom. 2020 03; 98(2):179-192.
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A population of CD20+CD27+CD43+CD38lo/int B1 cells in PNH are missing GPI-anchored proteins and harbor PIGA mutations. Blood. 2019 07 04; 134(1):89-92.
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Fatigue, symptom burden, and health-related quality of life in patients with myelodysplastic syndrome, aplastic anemia, and paroxysmal nocturnal hemoglobinuria. Cancer Med. 2019 02; 8(2):543-553.