"O Antigens" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The lipopolysaccharide-protein somatic antigens, usually from gram-negative bacteria, important in the serological classification of enteric bacilli. The O-specific chains determine the specificity of the O antigens of a given serotype. O antigens are the immunodominant part of the lipopolysaccharide molecule in the intact bacterial cell. (From Singleton & Sainsbury, Dictionary of Microbiology and Molecular Biology, 2d ed)
| Descriptor ID |
D019081
|
| MeSH Number(s) |
D09.698.718.450.600 D10.494.600 D23.050.161.616.525.600 D23.946.123.329.500.600
|
| Concept/Terms |
O Antigens- O Antigens
- Antigens, O
- O Antigen
- Antigen, O
- O-Specific Polysaccharides
- O Specific Polysaccharides
- Polysaccharides, O-Specific
- O-Specific Polysaccharide
- O Specific Polysaccharide
- Polysaccharide, O-Specific
- O Antigen, Bacterial
- Antigen, Bacterial O
- Bacterial O Antigen
- O-Antigens
|
Below are MeSH descriptors whose meaning is more general than "O Antigens".
Below are MeSH descriptors whose meaning is more specific than "O Antigens".
This graph shows the total number of publications written about "O Antigens" by people in this website by year, and whether "O Antigens" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2002 | 2 | 0 | 2 |
| 2003 | 1 | 0 | 1 |
| 2004 | 1 | 0 | 1 |
| 2005 | 2 | 0 | 2 |
| 2013 | 1 | 0 | 1 |
| 2017 | 0 | 1 | 1 |
| 2023 | 0 | 1 | 1 |
| 2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "O Antigens" by people in Profiles.
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Development of a Shigella conjugate vaccine targeting Shigella flexneri 6 that is immunogenic and provides protection against virulent challenge. Vaccine. 2024 10 24; 42(24):126263.
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Development of Shigella conjugate vaccines targeting Shigella flexneri 2a and S. flexneri 3a using a simple platform-approach conjugation by squaric acid chemistry. Vaccine. 2023 07 31; 41(34):4967-4977.
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Plasma and Mucosal Immunoglobulin M, Immunoglobulin A, and Immunoglobulin G Responses to the Vibrio cholerae O1 Protein Immunome in Adults With Cholera in Bangladesh. J Infect Dis. 2017 07 01; 216(1):125-134.
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Immune responses to the O-specific polysaccharide antigen in children who received a killed oral cholera vaccine compared to responses following natural cholera infection in Bangladesh. Clin Vaccine Immunol. 2013 Jun; 20(6):780-8.
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Lipopolysaccharide diversity evolving in Helicobacter pylori communities through genetic modifications in fucosyltransferases. PLoS One. 2008; 3(11):e3811.
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An enzymatic ruler modulates Lewis antigen glycosylation of Helicobacter pylori LPS during persistent infection. Proc Natl Acad Sci U S A. 2006 Feb 21; 103(8):2863-8.
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Evidence that WbpD is an N-acetyltransferase belonging to the hexapeptide acyltransferase superfamily and an important protein for O-antigen biosynthesis in Pseudomonas aeruginosa PAO1. Mol Microbiol. 2005 Sep; 57(5):1288-303.
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Functional characterization of WaaL, a ligase associated with linking O-antigen polysaccharide to the core of Pseudomonas aeruginosa lipopolysaccharide. J Bacteriol. 2005 May; 187(9):3002-12.
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Biochemical characterization of WbpA, a UDP-N-acetyl-D-glucosamine 6-dehydrogenase involved in O-antigen biosynthesis in Pseudomonas aeruginosa PAO1. J Biol Chem. 2004 Sep 03; 279(36):37551-8.
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Genetic modulation of Shigella flexneri 2a lipopolysaccharide O antigen modal chain length reveals that it has been optimized for virulence. Microbiology (Reading). 2003 Apr; 149(Pt 4):925-939.