"Apolipoprotein C-I" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 6.6-kDa protein component of VERY-LOW-DENSITY LIPOPROTEINS; INTERMEDIATE-DENSITY LIPOPROTEINS; and HIGH-DENSITY LIPOPROTEINS. Apo C-I displaces APO E from lipoproteins, modulate their binding to receptors (RECEPTORS, LDL), and thereby decrease their clearance from plasma. Elevated Apo C-I levels are associated with HYPERLIPOPROTEINEMIA and ATHEROSCLEROSIS.
| Descriptor ID |
D053302
|
| MeSH Number(s) |
D10.532.091.400.500 D12.776.070.400.400.500 D12.776.521.120.400.500
|
| Concept/Terms |
Apolipoprotein C-I Precursor- Apolipoprotein C-I Precursor
- Apolipoprotein C I Precursor
- Apo C-I Precursor
- Apo C I Precursor
- Pre Apo C-I
- Pre Apo C I
|
Below are MeSH descriptors whose meaning is more general than "Apolipoprotein C-I".
Below are MeSH descriptors whose meaning is more specific than "Apolipoprotein C-I".
This graph shows the total number of publications written about "Apolipoprotein C-I" by people in this website by year, and whether "Apolipoprotein C-I" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2011 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
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Below are the most recent publications written about "Apolipoprotein C-I" by people in Profiles.
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Genetic loci associated with ideal cardiovascular health: A meta-analysis of genome-wide association studies. Am Heart J. 2016 May; 175:112-20.
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A phenomics-based strategy identifies loci on APOC1, BRAP, and PLCG1 associated with metabolic syndrome phenotype domains. PLoS Genet. 2011 Oct; 7(10):e1002322.
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Gene expression signature analysis identifies vorinostat as a candidate therapy for gastric cancer. PLoS One. 2011; 6(9):e24662.
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Apolipoprotein E/C1 locus variants modify renal cell carcinoma risk. Cancer Res. 2009 Oct 15; 69(20):8001-8.
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Magnetic resonance studies of apolipoprotein C-I nitroxide labeled or [13C]methyl enriched at methionine-38. Biochemistry. 1980 Oct 28; 19(22):5140-6.