"Clodronic Acid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A diphosphonate which affects calcium metabolism. It inhibits bone resorption and soft tissue calcification.
| Descriptor ID |
D004002
|
| MeSH Number(s) |
D02.705.429.500.200
|
| Concept/Terms |
Clodronic Acid- Clodronic Acid
- Acid, Clodronic
- Dichloromethane Diphosphonate
- Diphosphonate, Dichloromethane
- Dichloromethylenebisphosphonate
- Dichloromethanediphosphonic Acid
- Acid, Dichloromethanediphosphonic
- Dichloromethylene Biphosphonate
- Biphosphonate, Dichloromethylene
- Dichloromethylene Diphosphonate
- Diphosphonate, Dichloromethylene
- Cl2MDP
- Dichloromethanediphosphonate
|
Below are MeSH descriptors whose meaning is more general than "Clodronic Acid".
Below are MeSH descriptors whose meaning is more specific than "Clodronic Acid".
This graph shows the total number of publications written about "Clodronic Acid" by people in this website by year, and whether "Clodronic Acid" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2015 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
| 2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "Clodronic Acid" by people in Profiles.
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Delayed macrophage targeting by clodronate liposomes worsens the progression of cytokine storm syndrome. Front Immunol. 2024; 15:1477449.
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Progression of EGFR-Mutant Lung Adenocarcinoma is Driven By Alveolar Macrophages. Clin Cancer Res. 2017 Feb 01; 23(3):778-788.
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LKB1 loss promotes endometrial cancer progression via CCL2-dependent macrophage recruitment. J Clin Invest. 2015 Nov 02; 125(11):4063-76.
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Consistent interactions between tumor cell IL-6 and macrophage TNF-a enhance the growth of human prostate cancer cells in the bone of nude mouse. Int Immunopharmacol. 2011 Jul; 11(7):862-72.
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Tumoricidal activity of high-dose tumor necrosis factor-alpha is mediated by macrophage-derived nitric oxide burst and permanent blood flow shutdown. Int J Cancer. 2008 Jul 15; 123(2):464-475.
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Safety of subcutaneous clodronate and efficacy in hypercalcemia of malignancy: a novel route of administration. J Pain Symptom Manage. 2003 Sep; 26(3):843-8.
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Subcutaneous clodronate: a study evaluating efficacy in hypercalcemia of malignancy and local toxicity. Ann Oncol. 1997 Sep; 8(9):915-6.
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Subcutaneous clodronate. Lancet. 1996 Aug 03; 348(9023):345-6.