Synaptosomal-Associated Protein 25
"Synaptosomal-Associated Protein 25" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A ubiquitous target SNARE protein that interacts with SYNTAXIN and SYNAPTOBREVIN. It is a core component of the machinery for intracellular MEMBRANE FUSION. The sequence contains 2 SNARE domains, one is the prototype for the Qb-SNARES, and the other is the prototype for the Qc-SNARES.
| Descriptor ID |
D050825
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| MeSH Number(s) |
D12.776.543.512.249.500.750.500 D12.776.543.512.249.500.875.500 D12.776.543.990.775.500.750.500 D12.776.543.990.775.500.875.500
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Synaptosomal-Associated Protein 25".
Below are MeSH descriptors whose meaning is more specific than "Synaptosomal-Associated Protein 25".
This graph shows the total number of publications written about "Synaptosomal-Associated Protein 25" by people in this website by year, and whether "Synaptosomal-Associated Protein 25" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 2 | 2 |
| 2006 | 0 | 1 | 1 |
| 2007 | 2 | 0 | 2 |
| 2008 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
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Below are the most recent publications written about "Synaptosomal-Associated Protein 25" by people in Profiles.
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Synaptotagmin-1 interacts with PI(4,5)P2 to initiate synaptic vesicle docking in hippocampal neurons. Cell Rep. 2021 03 16; 34(11):108842.
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NOS1 and SNAP25 polymorphisms are associated with Attention-Deficit/Hyperactivity Disorder symptoms in adults but not in children. J Psychiatr Res. 2016 Apr; 75:75-81.
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Sensation-seeking genes and physical activity in youth. Genes Brain Behav. 2013 Mar; 12(2):181-8.
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Mutations in the gene PRRT2 cause paroxysmal kinesigenic dyskinesia with infantile convulsions. Cell Rep. 2012 Jan 26; 1(1):2-12.
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Munc18a scaffolds SNARE assembly to promote membrane fusion. Mol Biol Cell. 2008 Dec; 19(12):5422-34.
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Differential abilities of SNAP-25 homologs to support neuronal function. J Neurosci. 2007 Aug 29; 27(35):9380-91.
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Synaptosomal-associated protein 25 gene expression is hormonally regulated during ovulation and is involved in cytokine/chemokine exocytosis from granulosa cells. Mol Endocrinol. 2007 Oct; 21(10):2487-502.
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The endosome-associated protein Hrs is hexameric and controls cargo sorting as a "master molecule". Structure. 2006 Apr; 14(4):661-71.
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Botulinum toxin in clinical practice. J Neurol Neurosurg Psychiatry. 2004 Jul; 75(7):951-7.
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Elevated thalamic low-voltage-activated currents precede the onset of absence epilepsy in the SNAP25-deficient mouse mutant coloboma. J Neurosci. 2004 Jun 02; 24(22):5239-48.