"Age of Onset" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The age, developmental stage, or period of life at which a disease or the initial symptoms or manifestations of a disease appear in an individual.
| Descriptor ID |
D017668
|
| MeSH Number(s) |
N05.715.350.075.100 N06.850.490.250.100
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Age of Onset".
Below are MeSH descriptors whose meaning is more specific than "Age of Onset".
This graph shows the total number of publications written about "Age of Onset" by people in this website by year, and whether "Age of Onset" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 5 | 5 |
| 1997 | 0 | 6 | 6 |
| 1998 | 0 | 9 | 9 |
| 1999 | 0 | 5 | 5 |
| 2000 | 0 | 10 | 10 |
| 2001 | 0 | 13 | 13 |
| 2002 | 1 | 6 | 7 |
| 2003 | 1 | 11 | 12 |
| 2004 | 0 | 18 | 18 |
| 2005 | 0 | 13 | 13 |
| 2006 | 0 | 13 | 13 |
| 2007 | 0 | 12 | 12 |
| 2008 | 0 | 13 | 13 |
| 2009 | 0 | 14 | 14 |
| 2010 | 0 | 24 | 24 |
| 2011 | 0 | 21 | 21 |
| 2012 | 0 | 30 | 30 |
| 2013 | 0 | 19 | 19 |
| 2014 | 2 | 15 | 17 |
| 2015 | 0 | 20 | 20 |
| 2016 | 2 | 22 | 24 |
| 2017 | 1 | 17 | 18 |
| 2018 | 1 | 18 | 19 |
| 2019 | 3 | 15 | 18 |
| 2020 | 0 | 24 | 24 |
| 2021 | 0 | 10 | 10 |
| 2022 | 1 | 4 | 5 |
| 2023 | 0 | 4 | 4 |
| 2024 | 4 | 10 | 14 |
| 2025 | 0 | 17 | 17 |
| 2026 | 0 | 2 | 2 |
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Below are the most recent publications written about "Age of Onset" by people in Profiles.
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Ultra-rare functional variants reveal early-onset breast cancer risk genes and pathways in the UK Biobank and All of Us Research Program. Am J Hum Genet. 2026 05 07; 113(5):1049-1066.
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ACTA2 Pathogenic Variants Activating Heat Shock Factor 1 and Increasing Cholesterol Biosynthesis in Smooth Muscle Cells Predispose to Early Onset Atherosclerosis. Circ Genom Precis Med. 2026 Feb; 19(1):e005169.
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Epigenetic age and telomere length correlations in pediatric-onset multiple sclerosis. Mult Scler. 2025 Dec; 31(14):1641-1650.
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Segmental and Multifocal Isolated Dystonias: Similarities and Differences. Mov Disord Clin Pract. 2026 Mar; 13(3):748-756.
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Mutations in the Key Autophagy Tethering Factor EPG5 Link Neurodevelopmental and Neurodegenerative Disorders Including Early-Onset Parkinsonism. Ann Neurol. 2025 11; 98(5):932-950.
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Intellectual and Neurodevelopmental Delays in Pediatric Catecholaminergic Polymorphic Ventricular Tachycardia: Distinct Characteristics and a More Malignant Neurocardiac Phenotype. Circ Arrhythm Electrophysiol. 2025 Oct; 18(10):e013437.
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Microbiome of Young and Later-Onset Colorectal Cancer. Surg Clin North Am. 2025 Oct; 105(5):925-939.
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Epigenetic Aging in Pediatric-Onset Multiple Sclerosis. Neurology. 2025 Jun 24; 104(12):e213673.
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Severe gastrointestinal manifestations in childhood-onset lupus: A single-center cohort and review of the literature. Lupus. 2025 Jun; 34(7):721-741.
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Prospective Associations Between Structural Brain Development and Onset of Depressive Disorder During Adolescence and Emerging Adulthood. Am J Psychiatry. 2025 Oct 01; 182(10):935-944.