Intervertebral Disc Degeneration
                             
                            
                            
                                
                            
                            
                                
                            
                            
                            
                                
                                    
                                            
	"Intervertebral Disc Degeneration" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, 
	MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, 
	which enables searching at various levels of specificity.
	
	
		
			
			
				Degenerative changes in the INTERVERTEBRAL DISC due to aging or structural damage, especially to the vertebral end-plates.
    
			
			
				
				
					
						| Descriptor ID | D055959 | 
					
						| MeSH Number(s) | C05.116.900.153 | 
					
						| Concept/Terms | Intervertebral Disc DegenerationIntervertebral Disc DegenerationDegeneration, Intervertebral DiscDegenerations, Intervertebral DiscDisc Degeneration, IntervertebralDisc Degenerations, IntervertebralIntervertebral Disc DegenerationsIntervertebral Disk DegenerationDegeneration, Intervertebral DiskDegenerations, Intervertebral DiskDisk Degeneration, IntervertebralDisk Degenerations, IntervertebralIntervertebral Disk DegenerationsDisk DegenerationDegeneration, DiskDegenerations, DiskDisk DegenerationsDisk DegradationDegradation, DiskDegradations, DiskDisk DegradationsDisc DegenerationDegeneration, DiscDegenerations, DiscDisc DegenerationsDisc DegradationDegradation, DiscDegradations, DiscDisc Degradations
 Degenerative Intervertebral DiscsDegenerative Intervertebral DiscsDegenerative Intervertebral DiscDisc, Degenerative IntervertebralDiscs, Degenerative IntervertebralIntervertebral Disc, DegenerativeIntervertebral Discs, DegenerativeDegenerative Intervertebral DisksDegenerative Intervertebral DiskDisk, Degenerative IntervertebralDisks, Degenerative IntervertebralIntervertebral Disk, DegenerativeIntervertebral Disks, Degenerative
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				Below are MeSH descriptors whose meaning is more general than "Intervertebral Disc Degeneration".
				
			 
			
			
				Below are MeSH descriptors whose meaning is more specific than "Intervertebral Disc Degeneration".
				
			 
		 
	 
 
                                        
                                            
	
	
		
			
			
					
				This graph shows the total number of publications written about "Intervertebral Disc Degeneration" by people in this website by year, and whether "Intervertebral Disc Degeneration" was a major or minor topic of these publications. 
				
					 
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		            | Year | Major Topic | Minor Topic | Total | 
|---|
| 2008 | 1 | 0 | 1 | 
| 2010 | 1 | 0 | 1 | 
| 2012 | 0 | 1 | 1 | 
| 2013 | 1 | 0 | 1 | 
| 2015 | 3 | 0 | 3 | 
| 2017 | 3 | 1 | 4 | 
| 2018 | 1 | 1 | 2 | 
| 2020 | 0 | 1 | 1 | 
| 2021 | 1 | 0 | 1 | 
| 2023 | 1 | 0 | 1 | 
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				Below are the most recent publications written about "Intervertebral Disc Degeneration" by people in Profiles.
						
					
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								ISSLS PRIZE in Clinical Science 2023: comparison of degenerative MRI features of the intervertebral disc between those with and without chronic low back pain. An exploratory study of two large female populations using automated annotation. Eur Spine J. 2023 05; 32(5):1504-1516. 
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								ISSLS PRIZE in Clinical Science 2022: Epidemiology, risk factors and clinical impact of juvenile Modic changes in paediatric patients with low back pain. Eur Spine J. 2022 05; 31(5):1069-1079. 
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								Platelet-Derived Biomaterials Inhibit Nicotine-Induced Intervertebral Disc Degeneration Through Regulating IGF-1/AKT/IRS-1 Signaling Axis. Cell Transplant. 2021 Jan-Dec; 30:9636897211045319. 
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								Teaching NeuroImages: Spinal cord infarct due to fibrocartilaginous embolism in an adolescent. Neurology. 2020 06 09; 94(23):e2495-e2496. 
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								Phlpp1 is associated with human intervertebral disc degeneration and its deficiency promotes healing after needle puncture injury in mice. Cell Death Dis. 2019 10 03; 10(10):754. 
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								Neurotoxic events associated with BCR-ABL1 tyrosine kinase inhibitors: a case series. Leuk Lymphoma. 2019 12; 60(13):3292-3295. 
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								Simultaneous lateral interbody fusion and pedicle screws (SLIPS) with CT-guided navigation. Clin Neurol Neurosurg. 2018 12; 175:91-97. 
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								Interobserver Reliability of Magnetic Resonance Imaging Predictors of Outcome in Cervical Spine Degenerative Conditions. World Neurosurg. 2018 Sep; 117:e215-e220. 
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								Safety and tolerability of intradiscal implantation of combined autologous adipose-derived mesenchymal stem cells and hyaluronic acid in patients with chronic discogenic low back pain: 1-year follow-up of a phase I study. Stem Cell Res Ther. 2017 Nov 15; 8(1):262. 
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								Effectiveness of Thermal Annular Procedures in Treating Discogenic Low Back Pain. Pain Physician. 2017 09; 20(6):447-470.