"Loperamide" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
One of the long-acting synthetic ANTIDIARRHEALS; it is not significantly absorbed from the gut, and has no effect on the adrenergic system or central nervous system, but may antagonize histamine and interfere with acetylcholine release locally.
| Descriptor ID |
D008139
|
| MeSH Number(s) |
D03.383.621.440
|
| Concept/Terms |
Loperamide Hydrochloride- Loperamide Hydrochloride
- Hydrochloride, Loperamide
- Loperamide Monohydrochloride
- Monohydrochloride, Loperamide
|
Below are MeSH descriptors whose meaning is more general than "Loperamide".
Below are MeSH descriptors whose meaning is more specific than "Loperamide".
This graph shows the total number of publications written about "Loperamide" by people in this website by year, and whether "Loperamide" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 2008 | 1 | 0 | 1 |
| 2009 | 0 | 1 | 1 |
| 2015 | 1 | 0 | 1 |
| 2017 | 0 | 1 | 1 |
| 2018 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Loperamide" by people in Profiles.
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Controlling faecal incontinence in women by performing anal exercises with biofeedback or loperamide: a randomised clinical trial. Lancet Gastroenterol Hepatol. 2019 09; 4(9):698-710.
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Loperamide Mimicking Brugada Pattern. Methodist Debakey Cardiovasc J. 2018 Oct-Dec; 14(4):e1-e3.
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Trial Evaluating Ambulatory Therapy of Travelers' Diarrhea (TrEAT TD) Study: A Randomized Controlled Trial Comparing 3 Single-Dose Antibiotic Regimens With Loperamide. Clin Infect Dis. 2017 Nov 29; 65(12):2008-2017.
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Loperamide Versus Psyllium Fiber for Treatment of Fecal Incontinence: The Fecal Incontinence Prescription (Rx) Management (FIRM) Randomized Clinical Trial. Dis Colon Rectum. 2015 Oct; 58(10):983-93.
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Diabetic diarrhea. Curr Gastroenterol Rep. 2009 Oct; 11(5):354-9.
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Outcomes of combination treatment of fecal incontinence in women. Am J Obstet Gynecol. 2008 Dec; 199(6):699.e1-7.
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Loperamide plus azithromycin more effectively treats travelers' diarrhea in Mexico than azithromycin alone. J Travel Med. 2007 Sep-Oct; 14(5):312-9.
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Treatment of travelers' diarrhea: randomized trial comparing rifaximin, rifaximin plus loperamide, and loperamide alone. Clin Gastroenterol Hepatol. 2007 Apr; 5(4):451-6.
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Phase II trial of irinotecan in patients with progressive or rapidly recurrent colorectal cancer. J Clin Oncol. 1996 Apr; 14(4):1128-35.
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Zaldaride maleate (a new calmodulin antagonist) versus loperamide in the treatment of traveler's diarrhea: randomized, placebo-controlled trial. Clin Infect Dis. 1995 Aug; 21(2):341-4.