"Ricin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A protein phytotoxin from the seeds of Ricinus communis, the castor oil plant. It agglutinates cells, is proteolytic, and causes lethal inflammation and hemorrhage if taken internally.
| Descriptor ID |
D012276
|
| MeSH Number(s) |
D08.811.277.450.430.700.750.666 D12.776.034.756 D12.776.503.499.937 D12.776.765.678.906.750
|
| Concept/Terms |
Ricin- Ricin
- Lectin, Castor Bean
- RCA60
- Ricinus Toxin
- Toxin, Ricinus
- RCA 60
- Castor Bean Lectin
- Lectin, Ricinus
- Ricinus Lectin
|
Below are MeSH descriptors whose meaning is more general than "Ricin".
Below are MeSH descriptors whose meaning is more specific than "Ricin".
This graph shows the total number of publications written about "Ricin" by people in this website by year, and whether "Ricin" was a major or minor topic of these publications.
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Below are the most recent publications written about "Ricin" by people in Profiles.
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A phase I study of a combination of anti-CD19 and anti-CD22 immunotoxins (Combotox) in adult patients with refractory B-lineage acute lymphoblastic leukaemia. Br J Haematol. 2011 Aug; 154(4):471-6.
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Conditional expression of UAS-transgenes in the adult eye with a new gene-switch vector system. Genesis. 2002 Sep-Oct; 34(1-2):127-31.
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Synergistic interaction between anti-p185HER-2 ricin A chain immunotoxins and radionuclide conjugates for inhibiting growth of ovarian and breast cancer cells that overexpress HER-2. Clin Cancer Res. 2000 Aug; 6(8):3334-41.
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Simultaneous detection of six biohazardous agents using a planar waveguide array biosensor. Biosens Bioelectron. 2000; 15(11-12):579-89.
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Cell surface density of p185(c-erbB-2) determines susceptibility to anti-p185(c-erbB-2)-ricin A chain (RTA) immunotoxin therapy alone and in combination with anti-p170(EGFR)-RTA in ovarian cancer cells. Clin Cancer Res. 1998 Oct; 4(10):2545-50.
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Ricin A-chain: kinetics, mechanism, and RNA stem-loop inhibitors. Biochemistry. 1998 Aug 18; 37(33):11605-13.
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A hypothesis to explain the substrate reactivity of ribosomal and stem-loop RNA with ricin A-chain. Toxicon. 1996 Nov-Dec; 34(11-12):1317-24.
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The tyrosine kinase activity of the C-erbB-2 gene product (p185) is required for growth inhibition by anti-p185 antibodies but not for the cytotoxicity of an anti-p185-ricin-A chain immunotoxin. Int J Cancer. 1994 Oct 15; 59(2):242-7.
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XomaZyme-CD5 immunotoxin in conjunction with partial T cell depletion for prevention of graft rejection and graft-versus-host disease after bone marrow transplantation from matched unrelated donors. Bone Marrow Transplant. 1994 May; 13(5):571-5.
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Alkylating agents and immunotoxins exert synergistic cytotoxic activity against ovarian cancer cells. Mechanism of action. J Clin Invest. 1993 Nov; 92(5):2440-7.