"Sincalide" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An octapeptide hormone present in the intestine and brain. When secreted from the gastric mucosa, it stimulates the release of bile from the gallbladder and digestive enzymes from the pancreas.
| Descriptor ID |
D012844
|
| MeSH Number(s) |
D06.472.317.152.700 D12.644.120.500
|
| Concept/Terms |
Sincalide- Sincalide
- CCK-OP
- OP-CCK
- H-Asp-Tyr(SO3H)-Met-Gly-Trp-Met-Asp-Phe-NH2
- Cholecystokinin Pancreozymin C-Terminal Octapeptide
- Cholecystokinin Pancreozymin C Terminal Octapeptide
- Syncalide
- CCK-8
- Cholecystokinin Octapeptide
SQ-19,844- SQ-19,844
- SQ 19,844
- SQ19,844
- SQ-19844
- SQ 19844
- SQ19844
|
Below are MeSH descriptors whose meaning is more general than "Sincalide".
Below are MeSH descriptors whose meaning is more specific than "Sincalide".
This graph shows the total number of publications written about "Sincalide" by people in this website by year, and whether "Sincalide" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 1 | 0 | 1 |
| 2008 | 0 | 1 | 1 |
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Below are the most recent publications written about "Sincalide" by people in Profiles.
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An NF-?B pathway-mediated positive feedback loop amplifies Ras activity to pathological levels in mice. J Clin Invest. 2012 Apr; 122(4):1519-28.
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Adenylyl cyclase-5 activity in the nucleus accumbens regulates anxiety-related behavior. J Neurochem. 2008 Oct; 107(1):105-15.
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Use of cholecystokinin-octapeptide for the prevention of parenteral nutrition-associated cholestasis. Pediatrics. 2005 May; 115(5):1332-40.
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Gallbladder muscle dysfunction in patients with chronic acalculous disease. Gastroenterology. 2001 Feb; 120(2):506-11.
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Impaired G protein function in gallbladder muscle from progesterone-treated guinea pigs. Am J Physiol. 1998 02; 274(2):G283-9.
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Different pathways mediate cholecystokinin actions in cholelithiasis. Am J Physiol. 1997 Apr; 272(4 Pt 1):G838-44.
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Membrane cholesterol alters gallbladder muscle contractility in prairie dogs. Am J Physiol. 1996 Jul; 271(1 Pt 1):G56-61.
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Direct G protein activation reverses impaired CCK signaling in human gallbladders with cholesterol stones. Am J Physiol. 1995 Nov; 269(5 Pt 1):G659-65.
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Pancreatic enzyme synthesis and turnover in human subjects. Am J Physiol. 1994 May; 266(5 Pt 1):G816-21.
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A cloned CCK-A receptor transduces multiple signals in response to full and partial agonists. Am J Physiol. 1993 Nov; 265(5 Pt 1):G999-1004.