"Sincalide" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An octapeptide hormone present in the intestine and brain. When secreted from the gastric mucosa, it stimulates the release of bile from the gallbladder and digestive enzymes from the pancreas.
| Descriptor ID |
D012844
|
| MeSH Number(s) |
D06.472.317.152.700 D12.644.120.500
|
| Concept/Terms |
Sincalide- Sincalide
- CCK-OP
- OP-CCK
- H-Asp-Tyr(SO3H)-Met-Gly-Trp-Met-Asp-Phe-NH2
- Cholecystokinin Pancreozymin C-Terminal Octapeptide
- Cholecystokinin Pancreozymin C Terminal Octapeptide
- Syncalide
- CCK-8
- Cholecystokinin Octapeptide
SQ-19,844- SQ-19,844
- SQ 19,844
- SQ19,844
- SQ-19844
- SQ 19844
- SQ19844
|
Below are MeSH descriptors whose meaning is more general than "Sincalide".
Below are MeSH descriptors whose meaning is more specific than "Sincalide".
This graph shows the total number of publications written about "Sincalide" by people in this website by year, and whether "Sincalide" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 |
| 1995 | 1 | 1 | 2 |
| 1996 | 1 | 2 | 3 |
| 1997 | 1 | 3 | 4 |
| 1998 | 0 | 1 | 1 |
| 1999 | 2 | 0 | 2 |
| 2000 | 1 | 0 | 1 |
| 2001 | 1 | 1 | 2 |
| 2002 | 1 | 0 | 1 |
| 2005 | 1 | 0 | 1 |
| 2007 | 1 | 0 | 1 |
| 2008 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
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Below are the most recent publications written about "Sincalide" by people in Profiles.
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The vagus nerve modulates BDNF expression and neurogenesis in the hippocampus. Eur Neuropsychopharmacol. 2018 02; 28(2):307-316.
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An NF-?B pathway-mediated positive feedback loop amplifies Ras activity to pathological levels in mice. J Clin Invest. 2012 Apr; 122(4):1519-28.
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Adenylyl cyclase-5 activity in the nucleus accumbens regulates anxiety-related behavior. J Neurochem. 2008 Oct; 107(1):105-15.
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Secretagogues differentially activate endoplasmic reticulum stress responses in pancreatic acinar cells. Am J Physiol Gastrointest Liver Physiol. 2007 Jun; 292(6):G1804-12.
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Use of cholecystokinin-octapeptide for the prevention of parenteral nutrition-associated cholestasis. Pediatrics. 2005 May; 115(5):1332-40.
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Human pancreatic acinar cells do not respond to cholecystokinin. Pharmacol Toxicol. 2002 Dec; 91(6):327-32.
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Human pancreatic acinar cells lack functional responses to cholecystokinin and gastrin. Gastroenterology. 2001 Dec; 121(6):1380-90.
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Gallbladder muscle dysfunction in patients with chronic acalculous disease. Gastroenterology. 2001 Feb; 120(2):506-11.
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Species differences between rat and mouse CCKA receptors determine the divergent acinar cell response to the cholecystokinin analog JMV-180. J Biol Chem. 2000 Jun 23; 275(25):19115-20.
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Cholecystokinin induction of mob-1 chemokine expression in pancreatic acinar cells requires NF-kappaB activation. Am J Physiol. 1999 07; 277(1):C74-82.