"Drug Inverse Agonism" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Phenomena and pharmaceutics of compounds that bind to the same receptor binding-site as an agonist (DRUG AGONISM) for that receptor but exerts the opposite pharmacological effect.
| Descriptor ID |
D054314
|
| MeSH Number(s) |
G07.690.773.968.393
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Drug Inverse Agonism".
Below are MeSH descriptors whose meaning is more specific than "Drug Inverse Agonism".
This graph shows the total number of publications written about "Drug Inverse Agonism" by people in this website by year, and whether "Drug Inverse Agonism" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2019 | 0 | 1 | 1 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Drug Inverse Agonism" by people in Profiles.
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Pimavanserin reverses multiple measures of anxiety in a rodent model of post-traumatic stress disorder. Eur J Pharmacol. 2023 Jan 15; 939:175437.
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A Selective ERRa/? Inverse Agonist, SLU-PP-1072, Inhibits the Warburg Effect and Induces Apoptosis in Prostate Cancer Cells. ACS Chem Biol. 2020 09 18; 15(9):2338-2345.
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Inverse agonists of the 5-HT2A receptor reduce nicotine withdrawal signs in rats. Neurosci Lett. 2019 11 20; 713:134524.
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beta-Adrenoceptor inverse agonists in asthma. Curr Opin Pharmacol. 2010 Jun; 10(3):254-9.
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On the intractability of estrogen-related receptor alpha as a target for activation by small molecules. J Med Chem. 2007 Dec 27; 50(26):6722-4.
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Getting to the heart of asthma: can "beta blockers" be useful to treat asthma? Pharmacol Ther. 2007 Sep; 115(3):360-74.