Clinical Trials Data Monitoring Committees
"Clinical Trials Data Monitoring Committees" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Committees established to review interim data and efficacy outcomes in clinical trials. The findings of these committees are used in deciding whether a trial should be continued as designed, changed, or terminated. Government regulations regarding federally-funded research involving human subjects (the "Common Rule") require (45 CFR 46.111) that research ethics committees reviewing large-scale clinical trials monitor the data collected using a mechanism such as a data monitoring committee. FDA regulations (21 CFR 50.24) require that such committees be established to monitor studies conducted in emergency settings.
| Descriptor ID |
D026661
|
| MeSH Number(s) |
N05.700.685.149
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| Concept/Terms |
Clinical Trials Data Monitoring Committees- Clinical Trials Data Monitoring Committees
- Data Monitoring Committees
- Committee, Data Monitoring
- Committees, Data Monitoring
- Data Monitoring Committee
- Monitoring Committee, Data
- Monitoring Committees, Data
- Safety Monitoring Boards
- Board, Safety Monitoring
- Boards, Safety Monitoring
- Monitoring Board, Safety
- Monitoring Boards, Safety
- Safety Monitoring Board
- Data and Safety Monitoring Boards
|
Below are MeSH descriptors whose meaning is more general than "Clinical Trials Data Monitoring Committees".
Below are MeSH descriptors whose meaning is more specific than "Clinical Trials Data Monitoring Committees".
This graph shows the total number of publications written about "Clinical Trials Data Monitoring Committees" by people in this website by year, and whether "Clinical Trials Data Monitoring Committees" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2018 | 0 | 1 | 1 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Clinical Trials Data Monitoring Committees" by people in Profiles.
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Clinical trials in a COVID-19 pandemic: Shared infrastructure for continuous learning in a rapidly changing landscape. Clin Trials. 2021 06; 18(3):324-334.
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Traumatic injury clinical trial evaluating tranexamic acid in children (TIC-TOC): study protocol for a pilot randomized controlled trial. Trials. 2018 Oct 30; 19(1):593.
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Data safety and monitoring boards. N Engl J Med. 2004 Jun 03; 350(23):2423;; author reply 2423.
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Ethical issues arising when interim data in clinical trials is restricted to independent data monitoring committees. IRB. 2000 Jan; 22(1):7-11.
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Secrecy for data monitoring committees: inferior ethics, bad policy. J Clin Oncol. 1998 Jan; 16(1):390-1.