Retinal Pigment Epithelium
"Retinal Pigment Epithelium" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The single layer of pigment-containing epithelial cells in the RETINA, situated closely to the tips (outer segments) of the RETINAL PHOTORECEPTOR CELLS. These epithelial cells are macroglia that perform essential functions for the photoreceptor cells, such as in nutrient transport, phagocytosis of the shed photoreceptor membranes, and ensuring retinal attachment.
| Descriptor ID |
D055213
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| MeSH Number(s) |
A09.371.670.500 A09.371.729.887
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Retinal Pigment Epithelium".
Below are MeSH descriptors whose meaning is more specific than "Retinal Pigment Epithelium".
This graph shows the total number of publications written about "Retinal Pigment Epithelium" by people in this website by year, and whether "Retinal Pigment Epithelium" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 1 | 0 | 1 |
| 2010 | 1 | 0 | 1 |
| 2011 | 1 | 1 | 2 |
| 2013 | 1 | 0 | 1 |
| 2014 | 2 | 1 | 3 |
| 2015 | 1 | 1 | 2 |
| 2016 | 0 | 1 | 1 |
| 2017 | 0 | 1 | 1 |
| 2018 | 2 | 4 | 6 |
| 2019 | 3 | 2 | 5 |
| 2020 | 1 | 2 | 3 |
| 2021 | 0 | 1 | 1 |
| 2022 | 1 | 0 | 1 |
| 2025 | 0 | 3 | 3 |
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Below are the most recent publications written about "Retinal Pigment Epithelium" by people in Profiles.
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THE "SCOLEX" SIGN: A Distinct Hyperreflective Foci on the Wall of Serous Pigment Epithelial Detachments in Central Serous Chorioretinopathy - Micron Report Number Seven. Retina. 2026 May 01; 46(5):871-880.
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Retinal Ischemia: Therapeutic Effects and Mechanisms of Paeoniflorin. Int J Mol Sci. 2025 Nov 11; 26(22).
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Loss of the lysosomal protein CLN3 triggers c-Abl-dependent YAP1 pro-apoptotic signaling. EMBO Rep. 2025 Dec; 26(24):6096-6120.
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Generation of human induced pluripotent stem cell lines from an age-related macular degeneration patient with hyperreflective foci overlying drusen (RFSCi002-A) and an unaffected sibling (RFSCi001-A). Stem Cell Res. 2025 Aug; 86:103715.
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Clinical Characteristics and Progression of Pachychoroid Macular Atrophy in Central Serous Chorioretinopathy. Ophthalmol Retina. 2025 Oct; 9(10):984-993.
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Topographic analysis of local OCT biomarkers which predict progression to atrophy in age-related macular degeneration. Graefes Arch Clin Exp Ophthalmol. 2024 Jul; 262(7):2083-2091.
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Riboflavin deficiency leads to irreversible cellular changes in the RPE and disrupts retinal function through alterations in cellular metabolic homeostasis. Redox Biol. 2022 08; 54:102375.
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Expanding the clinical phenotype in patients with disease causing variants associated with atypical Usher syndrome. Ophthalmic Genet. 2021 12; 42(6):664-673.
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Investigational Agents in Development for the Treatment of Geographic Atrophy Secondary to Age-Related Macular Degeneration. BioDrugs. 2021 May; 35(3):303-323.
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Epigenetic hallmarks of age-related macular degeneration are recapitulated in a photosensitive mouse model. Hum Mol Genet. 2020 08 29; 29(15):2611-2624.