"DCMP Deaminase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that catalyzes the hydrolytic deamination of deoxycytidylic acid to deoxyuridylic acid and ammonia. It plays an important role in the regulation of the pool of deoxynucleotides in higher organisms. The enzyme also acts on some 5-substituted deoxycytidylic acids. EC 3.5.4.12.
| Descriptor ID |
D003844
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| MeSH Number(s) |
D08.811.277.151.653.200
|
| Concept/Terms |
DCMP Deaminase- DCMP Deaminase
- Deaminase, DCMP
- Deoxycytidylate Aminohydrolase
- Aminohydrolase, Deoxycytidylate
- Deoxycytidylate Deaminase
- Deaminase, Deoxycytidylate
- Deoxycytidine Monophosphate Deaminase
- Deaminase, Deoxycytidine Monophosphate
- Monophosphate Deaminase, Deoxycytidine
|
Below are MeSH descriptors whose meaning is more general than "DCMP Deaminase".
Below are MeSH descriptors whose meaning is more specific than "DCMP Deaminase".
This graph shows the total number of publications written about "DCMP Deaminase" by people in this website by year, and whether "DCMP Deaminase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
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Below are the most recent publications written about "DCMP Deaminase" by people in Profiles.
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Gemcitabine: preclinical pharmacology and mechanisms of action. Semin Oncol. 1996 Oct; 23(5 Suppl 10):3-15.
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Modulation of deoxycytidylate deaminase in intact human leukemia cells. Action of 2',2'-difluorodeoxycytidine. Biochem Pharmacol. 1992 Nov 03; 44(9):1819-27.
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Cellular elimination of 2',2'-difluorodeoxycytidine 5'-triphosphate: a mechanism of self-potentiation. Cancer Res. 1992 Feb 01; 52(3):533-9.
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Metabolism and action of 2',2'-difluorodeoxycytidine: self-potentiation of cytotoxicity. Adv Exp Med Biol. 1991; 309A:125-30.
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Effect of tetrahydrouridine and deoxytetrahydrouridine on the interaction between 2'-deoxycytidine and 1-beta-D-arabinofuranosylcytosine in human leukemia cells. Leuk Res. 1991; 15(4):205-13.
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Modulation of deoxynucleotide metabolism by the deoxycytidylate deaminase inhibitor 3,4,5,6-tetrahydrodeoxyuridine. Biochem Pharmacol. 1989 Nov 15; 38(22):4115-21.