"Apolipoprotein A-II" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The second most abundant protein component of HIGH DENSITY LIPOPROTEINS or HDL. It has a high lipid affinity and is known to displace APOLIPOPROTEIN A-I from HDL particles and generates a stable HDL complex. ApoA-II can modulate the activation of LECITHIN CHOLESTEROL ACYLTRANSFERASE in the presence of APOLIPOPROTEIN A-I, thus affecting HDL metabolism.
Descriptor ID |
D016633
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MeSH Number(s) |
D10.532.091.200.150 D12.776.070.400.200.150 D12.776.521.120.200.150
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Concept/Terms |
Apolipoprotein A-II- Apolipoprotein A-II
- Apolipoprotein A II
- Apo A-II
- Apo A2
- Apo AII
- ApoA-II
- Apolipoprotein A-2
- Apolipoprotein A 2
- Apolipoprotein A2
- Apolipoprotein AII
- Apo A-2
- ApoA-2
Pro-Apolipoprotein A-II- Pro-Apolipoprotein A-II
- Pro Apolipoprotein A II
- Proapolipoprotein A-II
- Proapolipoprotein A II
- Pro-Apo A-II
- Pro Apo A II
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Below are MeSH descriptors whose meaning is more general than "Apolipoprotein A-II".
Below are MeSH descriptors whose meaning is more specific than "Apolipoprotein A-II".
This graph shows the total number of publications written about "Apolipoprotein A-II" by people in this website by year, and whether "Apolipoprotein A-II" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2001 | 0 | 1 | 1 |
2002 | 1 | 0 | 1 |
2008 | 0 | 1 | 1 |
2009 | 0 | 1 | 1 |
2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "Apolipoprotein A-II" by people in Profiles.
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Epigenomics and metabolomics reveal the mechanism of the APOA2-saturated fat intake interaction affecting obesity. Am J Clin Nutr. 2018 07 01; 108(1):188-200.
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SR-BI selective lipid uptake: subsequent metabolism of acute phase HDL. Arterioscler Thromb Vasc Biol. 2009 Sep; 29(9):1298-303.
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ESR1 polymorphism is associated with plasma lipid and apolipoprotein levels in Caucasians of the Rochester Family Heart Study. J Lipid Res. 2008 Aug; 49(8):1701-6.
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Sequence polymorphism at the human apolipoprotein AII gene ( APOA2): unexpected deficit of variation in an African-American sample. Hum Genet. 2002 Jul; 111(1):75-87.
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Genome-wide linkage analysis reveals evidence of multiple regions that influence variation in plasma lipid and apolipoprotein levels associated with risk of coronary heart disease. Arterioscler Thromb Vasc Biol. 2001 Jun; 21(6):971-8.
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Dietary intake and gene variation influence the response of plasma lipids to dietary intervention. Genet Epidemiol. 1992; 9(4):249-60.