Primary Ovarian Insufficiency
"Primary Ovarian Insufficiency" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cessation of ovarian function after MENARCHE but before the age of 40, without or with OVARIAN FOLLICLE depletion. It is characterized by the presence of OLIGOMENORRHEA or AMENORRHEA, elevated GONADOTROPINS, and low ESTRADIOL levels. It is a state of female HYPERGONADOTROPIC HYPOGONADISM. Etiologies include genetic defects, autoimmune processes, chemotherapy, radiation, and infections.
Descriptor ID |
D016649
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MeSH Number(s) |
C13.351.500.056.630.750 C19.391.630.750
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Concept/Terms |
Primary Ovarian Insufficiency- Primary Ovarian Insufficiency
- Insufficiency, Primary Ovarian
- Ovarian Insufficiency, Primary
- Premature Ovarian Failure
- Ovarian Failure, Premature
Hypergonadotropic Ovarian Failure, X-Linked- Hypergonadotropic Ovarian Failure, X-Linked
- Hypergonadotropic Ovarian Failure, X Linked
- FMR1-Related Primary Ovarian Insufficiency
- FMR1 Related Primary Ovarian Insufficiency
- Premature Ovarian Failure, X-Linked
- Premature Ovarian Failure, X Linked
- X-Linked Hypergonadotropic Ovarian Failure
- X Linked Hypergonadotropic Ovarian Failure
- Fragile X-Associated Primary Ovarian Insufficiency
- Fragile X Associated Primary Ovarian Insufficiency
- Premature Ovarian Failure 1
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Below are MeSH descriptors whose meaning is more general than "Primary Ovarian Insufficiency".
Below are MeSH descriptors whose meaning is more specific than "Primary Ovarian Insufficiency".
This graph shows the total number of publications written about "Primary Ovarian Insufficiency" by people in this website by year, and whether "Primary Ovarian Insufficiency" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1998 | 2 | 0 | 2 |
2001 | 1 | 0 | 1 |
2003 | 0 | 1 | 1 |
2004 | 1 | 1 | 2 |
2005 | 1 | 0 | 1 |
2006 | 0 | 1 | 1 |
2007 | 1 | 0 | 1 |
2008 | 4 | 0 | 4 |
2009 | 1 | 0 | 1 |
2011 | 0 | 1 | 1 |
2012 | 1 | 0 | 1 |
2013 | 3 | 3 | 6 |
2014 | 2 | 0 | 2 |
2016 | 3 | 1 | 4 |
2017 | 0 | 1 | 1 |
2018 | 2 | 1 | 3 |
2019 | 2 | 0 | 2 |
2020 | 1 | 0 | 1 |
2021 | 3 | 1 | 4 |
2022 | 2 | 0 | 2 |
2023 | 2 | 0 | 2 |
2024 | 2 | 0 | 2 |
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Below are the most recent publications written about "Primary Ovarian Insufficiency" by people in Profiles.
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Practice guideline on ovarian tissue cryopreservation and transplantation in the prevention and treatment of iatrogenic premature ovarian insufficiency. Maturitas. 2024 Apr; 182:107922.
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Ovarian Insufficiency and Fertility Preservation During and After Childhood Cancer Treatment. J Adolesc Young Adult Oncol. 2024 Jun; 13(3):377-388.
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Development and validation of age-specific risk prediction models for primary ovarian insufficiency in long-term survivors of childhood cancer: a report from the Childhood Cancer Survivor Study and St Jude Lifetime Cohort. Lancet Oncol. 2023 12; 24(12):1434-1442.
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Impact of ovarian insufficiency on bone health in childhood cancer survivors: Two cases. Bone. 2024 01; 178:116930.
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The diagnostic experience of women with fragile X-associated primary ovarian insufficiency (FXPOI). J Assist Reprod Genet. 2023 Jan; 40(1):179-190.
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TrkB agonist antibody ameliorates fertility deficits in aged and cyclophosphamide-induced premature ovarian failure model mice. Nat Commun. 2022 02 17; 13(1):914.
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Deletion of Gremlin-2 alters estrous cyclicity and disrupts female fertility in mice?. Biol Reprod. 2021 11 15; 105(5):1205-1220.
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Genetic insights into biological mechanisms governing human ovarian ageing. Nature. 2021 08; 596(7872):393-397.
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Ectopic expression of CGG-repeats alters ovarian response to gonadotropins and leads to infertility in a murine FMR1 premutation model. Hum Mol Genet. 2021 05 29; 30(10):923-938.
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Refining the risk for fragile X-associated primary ovarian insufficiency (FXPOI) by FMR1 CGG repeat size. Genet Med. 2021 09; 23(9):1648-1655.