Primary Ovarian Insufficiency
"Primary Ovarian Insufficiency" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cessation of ovarian function after MENARCHE but before the age of 40, without or with OVARIAN FOLLICLE depletion. It is characterized by the presence of OLIGOMENORRHEA or AMENORRHEA, elevated GONADOTROPINS, and low ESTRADIOL levels. It is a state of female HYPERGONADOTROPIC HYPOGONADISM. Etiologies include genetic defects, autoimmune processes, chemotherapy, radiation, and infections.
| Descriptor ID |
D016649
|
| MeSH Number(s) |
C13.351.500.056.630.750 C19.391.630.750
|
| Concept/Terms |
Primary Ovarian Insufficiency- Primary Ovarian Insufficiency
- Insufficiency, Primary Ovarian
- Ovarian Insufficiency, Primary
- Premature Ovarian Failure
- Ovarian Failure, Premature
Hypergonadotropic Ovarian Failure, X-Linked- Hypergonadotropic Ovarian Failure, X-Linked
- Hypergonadotropic Ovarian Failure, X Linked
- FMR1-Related Primary Ovarian Insufficiency
- FMR1 Related Primary Ovarian Insufficiency
- Premature Ovarian Failure, X-Linked
- Premature Ovarian Failure, X Linked
- X-Linked Hypergonadotropic Ovarian Failure
- X Linked Hypergonadotropic Ovarian Failure
- Fragile X-Associated Primary Ovarian Insufficiency
- Fragile X Associated Primary Ovarian Insufficiency
- Premature Ovarian Failure 1
|
Below are MeSH descriptors whose meaning is more general than "Primary Ovarian Insufficiency".
Below are MeSH descriptors whose meaning is more specific than "Primary Ovarian Insufficiency".
This graph shows the total number of publications written about "Primary Ovarian Insufficiency" by people in this website by year, and whether "Primary Ovarian Insufficiency" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 2 | 0 | 2 |
| 2001 | 1 | 0 | 1 |
| 2004 | 1 | 0 | 1 |
| 2006 | 0 | 1 | 1 |
| 2007 | 1 | 0 | 1 |
| 2008 | 1 | 0 | 1 |
| 2011 | 0 | 1 | 1 |
| 2013 | 2 | 2 | 4 |
| 2014 | 2 | 0 | 2 |
| 2016 | 2 | 0 | 2 |
| 2017 | 0 | 1 | 1 |
| 2018 | 2 | 0 | 2 |
| 2019 | 3 | 0 | 3 |
| 2021 | 3 | 1 | 4 |
| 2023 | 1 | 0 | 1 |
| 2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "Primary Ovarian Insufficiency" by people in Profiles.
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Ovarian Insufficiency and Fertility Preservation During and After Childhood Cancer Treatment. J Adolesc Young Adult Oncol. 2024 06; 13(3):377-388.
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Impact of ovarian insufficiency on bone health in childhood cancer survivors: Two cases. Bone. 2024 01; 178:116930.
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Deletion of Gremlin-2 alters estrous cyclicity and disrupts female fertility in mice?. Biol Reprod. 2021 11 15; 105(5):1205-1220.
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Galactosaemia occurring in association with primary ovarian insufficiency, Addison's disease and chronic myeloid leukaemia. BMJ Case Rep. 2021 Aug 25; 14(8).
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Genetic insights into biological mechanisms governing human ovarian ageing. Nature. 2021 08; 596(7872):393-397.
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Ectopic expression of CGG-repeats alters ovarian response to gonadotropins and leads to infertility in a murine FMR1 premutation model. Hum Mol Genet. 2021 05 29; 30(10):923-938.
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Primary ovarian insufficiency in an adolescent population: clinical phenotype and diagnostic approach. J Pediatr Endocrinol Metab. 2019 Sep 25; 32(9):979-985.
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Assessment of ovarian function in adolescents and young adults after childhood cancer treatment-How accurate are young adult/parent proxy-reported outcomes? Pediatr Blood Cancer. 2019 12; 66(12):e27981.
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Exome Sequencing of a Primary Ovarian Insufficiency Cohort Reveals Common Molecular Etiologies for a Spectrum of Disease. J Clin Endocrinol Metab. 2019 08 01; 104(8):3049-3067.
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Noncytotoxic-Related Primary Ovarian Insufficiency in Adolescents: Multicenter Case Series and Review. J Pediatr Adolesc Gynecol. 2018 Dec; 31(6):597-604.