"Aflatoxin M1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 4-hydroxylated metabolite of AFLATOXIN B1, one of the MYCOTOXINS from ASPERGILLUS tainted food. It is associated with LIVER damage and cancer resulting from its P450 activation to the epoxide which alkylates DNA. Toxicity depends on the balance of liver enzymes that activate it (CYTOCHROME P-450) and others that detoxify it (GLUTATHIONE S TRANSFERASE) (Pharmac Ther 50.443 1991). Primates & rat are sensitive while mouse and hamster are tolerant (Canc Res 29.236 1969).
| Descriptor ID |
D016607
|
| MeSH Number(s) |
D03.383.663.283.119.100 D03.633.100.150.119.100 D23.946.587.142.100
|
| Concept/Terms |
Aflatoxin M1- Aflatoxin M1
- 4-Hydroxyaflatoxin B1
- 4 Hydroxyaflatoxin B1
|
Below are MeSH descriptors whose meaning is more general than "Aflatoxin M1".
Below are MeSH descriptors whose meaning is more specific than "Aflatoxin M1".
This graph shows the total number of publications written about "Aflatoxin M1" by people in this website by year, and whether "Aflatoxin M1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
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Below are the most recent publications written about "Aflatoxin M1" by people in Profiles.
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[Using HTS-ELISA method to make anti-aflatoxin M1 monoclonal antibody]. Wei Sheng Wu Xue Bao. 2010 Oct; 50(10):1406-11.
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A Bayesian approach estimating treatment effects on biomarkers containing zeros with detection limits. Stat Med. 2008 Jun 15; 27(13):2497-508.
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Immunoaffinity column clean-up for the high-performance liquid chromatographic determination of aflatoxins B1, B2, G1, G2, M1 and Q1 in urine. J Chromatogr B Biomed Appl. 1995 Oct 20; 672(2):253-9.