"Nicorandil" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A derivative of the NIACINAMIDE that is structurally combined with an organic nitrate. It is a potassium-channel opener that causes vasodilatation of arterioles and large coronary arteries. Its nitrate-like properties produce venous vasodilation through stimulation of guanylate cyclase.
| Descriptor ID |
D020108
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| MeSH Number(s) |
D02.583.575 D03.066.515.530.498 D03.383.725.547.530.498
|
| Concept/Terms |
Nicorandil- Nicorandil
- 2-Nicotinamidoethyl Nitrate
- 2 Nicotinamidoethyl Nitrate
- Nitrate, 2-Nicotinamidoethyl
- 2-Nicotinamidethyl Nitrate
- 2 Nicotinamidethyl Nitrate
- Nitrate, 2-Nicotinamidethyl
|
Below are MeSH descriptors whose meaning is more general than "Nicorandil".
Below are MeSH descriptors whose meaning is more specific than "Nicorandil".
This graph shows the total number of publications written about "Nicorandil" by people in this website by year, and whether "Nicorandil" was a major or minor topic of these publications.
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Below are the most recent publications written about "Nicorandil" by people in Profiles.
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Cardiac preconditioning during percutaneous coronary interventions. Cardiovasc Drugs Ther. 2005 May; 19(3):211-7.
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Use of potassium channel openers for pharmacologic modulation of cardiac excitability. J Cardiovasc Electrophysiol. 2004 Jul; 15(7):821-3.
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A further study of the vasodilator and negative inotropic mechanisms of action of nicorandil and its congeners in the canine heart. Cardiovasc Drugs Ther. 1994 Apr; 8(2):227-34.
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Specific but differential antagonism by glibenclamide of the vasodepressor effects of cromakalim and nicorandil in spinally-anaesthetized dogs. Br J Pharmacol. 1990 Jul; 100(3):413-6.