"Dimethyl Sulfoxide" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A highly polar organic liquid, that is used widely as a chemical solvent. Because of its ability to penetrate biological membranes, it is used as a vehicle for topical application of pharmaceuticals. It is also used to protect tissue during CRYOPRESERVATION. Dimethyl sulfoxide shows a range of pharmacological activity including analgesia and anti-inflammation.
| Descriptor ID |
D004121
|
| MeSH Number(s) |
D02.886.640.150
|
| Concept/Terms |
Dimethyl Sulfoxide- Dimethyl Sulfoxide
- Sulfoxide, Dimethyl
- Dimethylsulphinyl
- Sulfinylbis(methane)
- Dimethyl Sulphoxide
- Sulphoxide, Dimethyl
- Dimethylsulfoxide
- Dimethylsulphoxide
- DMSO
|
Below are MeSH descriptors whose meaning is more general than "Dimethyl Sulfoxide".
Below are MeSH descriptors whose meaning is more specific than "Dimethyl Sulfoxide".
This graph shows the total number of publications written about "Dimethyl Sulfoxide" by people in this website by year, and whether "Dimethyl Sulfoxide" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 |
| 2005 | 1 | 1 | 2 |
| 2007 | 1 | 1 | 2 |
| 2014 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
| 2020 | 1 | 1 | 2 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Dimethyl Sulfoxide" by people in Profiles.
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Comparing visualization performance of liquid embolic agents using a novel injectable phantom. Interv Neuroradiol. 2026 Oct; 32(5):2447-2454.
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Single-Cell Distribution Analysis of AR Levels by High-Throughput Microscopy in Cell Models: Application for Testing Endocrine-Disrupting Chemicals. SLAS Discov. 2020 08; 25(7):684-694.
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Microfluidic Cell Deformability Assay for Rapid and Efficient Kinase Screening with the CRISPR-Cas9 System. Angew Chem Int Ed Engl. 2016 07 18; 55(30):8561-5.
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Dimethyl sulfoxide enhances effectiveness of skin antiseptics and reduces contamination rates of blood cultures. J Clin Microbiol. 2012 May; 50(5):1552-7.
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Identification of direct serum-response factor gene targets during Me2SO-induced P19 cardiac cell differentiation. J Biol Chem. 2005 May 13; 280(19):19115-26.
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A randomized phase III clinical trial of autologous blood stem cell transplantation comparing cryopreservation using dimethylsulfoxide vs dimethylsulfoxide with hydroxyethylstarch. Bone Marrow Transplant. 2003 Jun; 31(11):1043-51.
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Topoisomerase II antagonism and anticancer activity of coordinated derivatives of [RuCl(2)(C(6)H(6))(dmso)]. Arch Biochem Biophys. 2002 May 01; 401(1):53-62.
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Inhibition of topoisomerase II catalytic activity by two ruthenium compounds: a ligand-dependent mode of action. Biochemistry. 1999 Apr 06; 38(14):4382-8.
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Enhanced retention of in vitro functional activity of platelets from recombinant human thrombopoietin-treated patients following long-term cryopreservation with a platelet-preserving solution (ThromboSol) and 2% DMSO. Br J Haematol. 1999 Feb; 104(2):403-11.
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Post-thaw removal of DMSO does not completely abrogate infusional toxicity or the need for pre-infusion histamine blockade. Cytotherapy. 1999; 1(6):439-46.