4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine
"4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A dual inhibitor of both cyclooxygenase and lipoxygenase pathways. It exerts an anti-inflammatory effect by inhibiting the formation of prostaglandins and leukotrienes. The drug also enhances pulmonary hypoxic vasoconstriction and has a protective effect after myocardial ischemia.
| Descriptor ID |
D015772
|
| MeSH Number(s) |
D03.383.129.539.120
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine".
Below are MeSH descriptors whose meaning is more specific than "4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine".
This graph shows the total number of publications written about "4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine" by people in this website by year, and whether "4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine" was a major or minor topic of these publications.
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Below are the most recent publications written about "4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine" by people in Profiles.
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Limitation of myocardial infarct size in pigs with a dual lipoxygenase-cyclooxygenase blocking agent by inhibition of neutrophil activity without reduction of neutrophil migration. J Am Coll Cardiol. 1993 Nov 15; 22(6):1738-44.