"Transglutaminases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Transglutaminases catalyze cross-linking of proteins at a GLUTAMINE in one chain with LYSINE in another chain. They include keratinocyte transglutaminase (TGM1 or TGK), tissue transglutaminase (TGM2 or TGC), plasma transglutaminase involved with coagulation (FACTOR XIII and FACTOR XIIIa), hair follicle transglutaminase, and prostate transglutaminase. Although structures differ, they share an active site (YGQCW) and strict CALCIUM dependence.
| Descriptor ID |
D011503
|
| MeSH Number(s) |
D08.811.913.050.200.800
|
| Concept/Terms |
Transglutaminases- Transglutaminases
- Protein-Glutamine gamma-Glutamyltransferases
- Protein Glutamine gamma Glutamyltransferases
- gamma-Glutamyltransferases, Protein-Glutamine
- Glutaminyl-Peptide Gamma-Glutamyltransferases
- Gamma-Glutamyltransferases, Glutaminyl-Peptide
- Glutaminyl Peptide Gamma Glutamyltransferases
|
Below are MeSH descriptors whose meaning is more general than "Transglutaminases".
Below are MeSH descriptors whose meaning is more specific than "Transglutaminases".
This graph shows the total number of publications written about "Transglutaminases" by people in this website by year, and whether "Transglutaminases" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 1 | 2 | 3 |
| 2007 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
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Below are the most recent publications written about "Transglutaminases" by people in Profiles.
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Microbial associations and viruses on the risk of celiac disease (MAVRiC): a longitudinal post-hoc case-cohort study. Sci Rep. 2025 Nov 28; 15(1):42704.
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Path Towards Biopsy-Free Diagnosis of Celiac Disease in Pediatric Patients. Clin Chim Acta. 2024 Apr 15; 557:117891.
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Cross-species genetic screens identify transglutaminase 5 as a regulator of polyglutamine-expanded ataxin-1. J Clin Invest. 2022 05 02; 132(9).
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Metagenomics of the faecal virome indicate a cumulative effect of enterovirus and gluten amount on the risk of coeliac disease autoimmunity in genetically at risk children: the TEDDY study. Gut. 2020 08; 69(8):1416-1422.
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Celiac disease is uncommon in irritable bowel syndrome in the USA. Eur J Gastroenterol Hepatol. 2018 Feb; 30(2):149-154.
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Testing for antireticulin antibodies in patients with celiac disease is obsolete: a review of recommendations for serologic screening and the literature. Clin Vaccine Immunol. 2013 Apr; 20(4):447-51.
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Calcium blockers decrease the bortezomib resistance in mantle cell lymphoma via manipulation of tissue transglutaminase activities. Blood. 2012 Mar 15; 119(11):2568-78.
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Clinical and histological presentation of Helicobacter pylori and gluten related gastroenteropathy. Arch Iran Med. 2011 03; 14(2):115-8.
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Cystic fibrosis: a disorder with defective autophagy. Autophagy. 2011 Jan; 7(1):104-6.
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Defective CFTR induces aggresome formation and lung inflammation in cystic fibrosis through ROS-mediated autophagy inhibition. Nat Cell Biol. 2010 Sep; 12(9):863-75.