Connection

CHRIS AMOS to Germ-Line Mutation

This is a "connection" page, showing publications CHRIS AMOS has written about Germ-Line Mutation.
Connection Strength

2.065
  1. Tumor somatic mutations also existing as germline polymorphisms may help to identify functional SNPs from genome-wide association studies. Carcinogenesis. 2020 10 15; 41(10):1353-1362.
    View in: PubMed
    Score: 0.573
  2. Effects of MDM2, MDM4 and TP53 codon 72 polymorphisms on cancer risk in a cohort study of carriers of TP53 germline mutations. PLoS One. 2010 May 26; 5(5):e10813.
    View in: PubMed
    Score: 0.279
  3. Focused Analysis of Exome Sequencing Data for Rare Germline Mutations in Familial and Sporadic Lung Cancer. J Thorac Oncol. 2016 Jan; 11(1):52-61.
    View in: PubMed
    Score: 0.103
  4. Germline mutations in shelterin complex genes are associated with familial glioma. J Natl Cancer Inst. 2015 Jan; 107(1):384.
    View in: PubMed
    Score: 0.095
  5. The effect on melanoma risk of genes previously associated with telomere length. J Natl Cancer Inst. 2014 Oct; 106(10).
    View in: PubMed
    Score: 0.094
  6. Underestimation of risk of a BRCA1 or BRCA2 mutation in women with high-grade serous ovarian cancer by BRCAPRO: a multi-institution study. J Clin Oncol. 2014 Apr 20; 32(12):1249-55.
    View in: PubMed
    Score: 0.091
  7. Sex-specific effect of the TP53 PIN3 polymorphism on cancer risk in a cohort study of TP53 germline mutation carriers. Hum Genet. 2011 Dec; 130(6):789-94.
    View in: PubMed
    Score: 0.075
  8. Joint effects of germ-line TP53 mutation, MDM2 SNP309, and gender on cancer risk in family studies of Li-Fraumeni syndrome. Hum Genet. 2011 Jun; 129(6):663-73.
    View in: PubMed
    Score: 0.073
  9. Joint effects of germ-line p53 mutation and sex on cancer risk in Li-Fraumeni syndrome. Cancer Res. 2006 Aug 15; 66(16):8287-92.
    View in: PubMed
    Score: 0.054
  10. Lung cancer risk in germline p53 mutation carriers: association between an inherited cancer predisposition, cigarette smoking, and cancer risk. Hum Genet. 2003 Aug; 113(3):238-43.
    View in: PubMed
    Score: 0.043
  11. Pathway-driven rare germline variants associated with transplant-associated thrombotic microangiopathy (TA-TMA). Thromb Res. 2023 05; 225:39-46.
    View in: PubMed
    Score: 0.042
  12. Germline p53 mutations in a cohort with childhood sarcoma: sex differences in cancer risk. Am J Hum Genet. 2003 Apr; 72(4):975-83.
    View in: PubMed
    Score: 0.042
  13. A validation of models for prediction of pathogenic variants in mismatch repair genes. Genet Med. 2022 10; 24(10):2155-2166.
    View in: PubMed
    Score: 0.041
  14. Clonal Hematopoiesis and Mosaicism Revealed by a Multi-Tissue Analysis of Constitutional TP53 Status. Cancer Epidemiol Biomarkers Prev. 2022 08 02; 31(8):1621-1629.
    View in: PubMed
    Score: 0.041
  15. Germline Pathogenic Variants Impact Clinicopathology of Advanced Lung Cancer. Cancer Epidemiol Biomarkers Prev. 2022 07 01; 31(7):1450-1459.
    View in: PubMed
    Score: 0.040
  16. Age-associated risk of cancer among individuals with N-acetyltransferase 2 (NAT2) mutations and mutations in DNA mismatch repair genes. Cancer Res. 2001 Feb 15; 61(4):1269-71.
    View in: PubMed
    Score: 0.037
  17. Protein-altering germline mutations implicate novel genes related to lung cancer development. Nat Commun. 2020 05 11; 11(1):2220.
    View in: PubMed
    Score: 0.035
  18. Penetrance Estimates Over Time to First and Second Primary Cancer Diagnosis in Families with Li-Fraumeni Syndrome: A Single Institution Perspective. Cancer Res. 2020 01 15; 80(2):347-353.
    View in: PubMed
    Score: 0.034
  19. Penetrance of Different Cancer Types in Families with Li-Fraumeni Syndrome: A Validation Study Using Multicenter Cohorts. Cancer Res. 2020 01 15; 80(2):354-360.
    View in: PubMed
    Score: 0.034
  20. Germline mutations in the extracellular domains of the 55 kDa TNF receptor, TNFR1, define a family of dominantly inherited autoinflammatory syndromes. Cell. 1999 Apr 02; 97(1):133-44.
    View in: PubMed
    Score: 0.032
  21. Exclusion of a p53 germline mutation in a classic Li-Fraumeni syndrome family. Hum Genet. 1998 Jun; 102(6):681-6.
    View in: PubMed
    Score: 0.030
  22. The role of germline polymorphisms in the T-cell receptor in susceptibility to ankylosing spondylitis. Br J Rheumatol. 1998 Apr; 37(4):454-8.
    View in: PubMed
    Score: 0.030
  23. Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases: A Mendelian Randomization Study. JAMA Oncol. 2017 May 01; 3(5):636-651.
    View in: PubMed
    Score: 0.028
  24. A recurrent mutation in PARK2 is associated with familial lung cancer. Am J Hum Genet. 2015 Feb 05; 96(2):301-8.
    View in: PubMed
    Score: 0.024
  25. Chemopreventive efficacy of rapamycin on Peutz-Jeghers syndrome in a mouse model. Cancer Lett. 2009 May 18; 277(2):149-54.
    View in: PubMed
    Score: 0.016
  26. EGFR-T790M is a rare lung cancer susceptibility allele with enhanced kinase activity. Cancer Res. 2007 May 15; 67(10):4665-70.
    View in: PubMed
    Score: 0.014
  27. Association between Aurora-A kinase polymorphisms and age of onset of hereditary nonpolyposis colorectal cancer in a Caucasian population. Mol Carcinog. 2007 Apr; 46(4):249-56.
    View in: PubMed
    Score: 0.014
  28. ATM polymorphism and hereditary nonpolyposis colorectal cancer (HNPCC) age of onset (United States). Cancer Causes Control. 2005 Aug; 16(6):749-53.
    View in: PubMed
    Score: 0.012
  29. Correlation of staining for LKB1 and COX-2 in hamartomatous polyps and carcinomas from patients with Peutz-Jeghers syndrome. J Histochem Cytochem. 2003 Dec; 51(12):1665-72.
    View in: PubMed
    Score: 0.011
  30. Common deletion of SMAD4 in juvenile polyposis is a mutational hotspot. Am J Hum Genet. 2002 May; 70(5):1357-62.
    View in: PubMed
    Score: 0.010
  31. Individual-specific liability groups in genetic linkage, with applications to kindreds with Li-Fraumeni syndrome. Am J Hum Genet. 2002 Mar; 70(3):813-7.
    View in: PubMed
    Score: 0.010
  32. Loci for efficient detection of microsatellite instability in hereditary non-polyposis colorectal cancer. Oncol Rep. 1999 May-Jun; 6(3):497-505.
    View in: PubMed
    Score: 0.008
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.