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This is a "connection" page, showing publications co-authored by RAGHU KALLURI and VALERIE LEBLEU.
RAGHU KALLURI
Connection Strength
14.393
VALERIE LEBLEU
  1. Genetic reprogramming with stem cells regenerates glomerular epithelial podocytes in Alport syndrome. Life Sci Alliance. 2024 Jun; 7(6).
    View in: PubMed
    Score: 0.957
  2. Identification of unique a4 chain structure and conserved antiangiogenic activity of a3NC1 type IV collagen in zebrafish. Dev Dyn. 2023 07; 252(7):1046-1060.
    View in: PubMed
    Score: 0.895
  3. Exosomes as a Multicomponent Biomarker Platform in Cancer. Trends Cancer. 2020 09; 6(9):767-774.
    View in: PubMed
    Score: 0.727
  4. The biology, function, and biomedical applications of exosomes. Science. 2020 02 07; 367(6478).
    View in: PubMed
    Score: 0.718
  5. Exosomes Exercise Inhibition of Anti-Tumor Immunity during Chemotherapy. Immunity. 2019 03 19; 50(3):547-549.
    View in: PubMed
    Score: 0.675
  6. A peek into cancer-associated fibroblasts: origins, functions and translational impact. Dis Model Mech. 2018 04 19; 11(4).
    View in: PubMed
    Score: 0.633
  7. Discovery of Double-Stranded Genomic DNA in Circulating Exosomes. Cold Spring Harb Symp Quant Biol. 2016; 81:275-280.
    View in: PubMed
    Score: 0.591
  8. PGC-1a mediates mitochondrial biogenesis and oxidative phosphorylation in cancer cells to promote?metastasis. Nat Cell Biol. 2014 Oct; 16(10):992-1003, 1-15.
    View in: PubMed
    Score: 0.494
  9. Origin and function of myofibroblasts in kidney fibrosis. Nat Med. 2013 Aug; 19(8):1047-53.
    View in: PubMed
    Score: 0.454
  10. Blockade of PDGF receptor signaling reduces myofibroblast number and attenuates renal fibrosis. Kidney Int. 2011 Dec; 80(11):1119-21.
    View in: PubMed
    Score: 0.407
  11. Identification of the NC1 domain of {alpha}3 chain as critical for {alpha}3{alpha}4{alpha}5 type IV collagen network assembly. J Biol Chem. 2010 Dec 31; 285(53):41874-85.
    View in: PubMed
    Score: 0.374
  12. Stem cell therapies benefit Alport syndrome. J Am Soc Nephrol. 2009 Nov; 20(11):2359-70.
    View in: PubMed
    Score: 0.351
  13. Stem cell-based therapy for glomerular diseases: an evolving concept. J Am Soc Nephrol. 2008 Sep; 19(9):1621-3.
    View in: PubMed
    Score: 0.324
  14. Lymphocytes are dispensable for glomerulonephritis but required for renal interstitial fibrosis in matrix defect-induced Alport renal disease. Lab Invest. 2008 Mar; 88(3):284-92.
    View in: PubMed
    Score: 0.310
  15. Structure and function of basement membranes. Exp Biol Med (Maywood). 2007 Oct; 232(9):1121-9.
    View in: PubMed
    Score: 0.305
  16. Vascular heterogeneity of tight junction Claudins guides organotropic metastasis. Nat Cancer. 2024 Sep; 5(9):1371-1389.
    View in: PubMed
    Score: 0.247
  17. Development of an engineered extracellular vesicles-based vaccine platform for combined delivery of mRNA and protein to induce functional immunity. J Control Release. 2024 Oct; 374:550-562.
    View in: PubMed
    Score: 0.246
  18. Engineered immunomodulatory extracellular vesicles derived from epithelial cells acquire capacity for positive and negative T cell co-stimulation in cancer and autoimmunity. bioRxiv. 2023 Nov 04.
    View in: PubMed
    Score: 0.232
  19. KRASG12D inhibition reprograms the microenvironment of early and advanced pancreatic cancer to promote FAS-mediated killing by CD8+ T?cells. Cancer Cell. 2023 09 11; 41(9):1606-1620.e8.
    View in: PubMed
    Score: 0.229
  20. Elimination of oncogenic KRAS in genetic mouse models eradicates pancreatic cancer by inducing FAS-dependent apoptosis by CD8+ T?cells. Dev Cell. 2023 09 11; 58(17):1562-1577.e8.
    View in: PubMed
    Score: 0.229
  21. Oncogenic Kras G12D specific non-covalent inhibitor reprograms tumor microenvironment to prevent and reverse early pre-neoplastic pancreatic lesions and in combination with immunotherapy regresses advanced PDAC in a CD8 + T cells dependent manner. bioRxiv. 2023 Feb 18.
    View in: PubMed
    Score: 0.221
  22. Engineered exosomes targeting MYC reverse the proneural-mesenchymal transition and extend survival of glioblastoma. Extracell Vesicle. 2022 Dec; 1.
    View in: PubMed
    Score: 0.217
  23. Author Correction: Glypican-1 identifies cancer exosomes and detects early pancreatic cancer. Nature. 2022 Oct; 610(7932):E15-E17.
    View in: PubMed
    Score: 0.216
  24. Identification of Functional Heterogeneity of Carcinoma-Associated Fibroblasts with Distinct IL6-Mediated Therapy Resistance in Pancreatic Cancer. Cancer Discov. 2022 06 02; 12(6):1580-1597.
    View in: PubMed
    Score: 0.211
  25. Dermal aSMA+ myofibroblasts orchestrate skin wound repair via ?1 integrin and independent of type I collagen production. EMBO J. 2022 04 04; 41(7):e109470.
    View in: PubMed
    Score: 0.207
  26. Exosome-mediated delivery of CRISPR/Cas9 for targeting of oncogenic KrasG12D in pancreatic cancer. Life Sci Alliance. 2021 09; 4(9).
    View in: PubMed
    Score: 0.198
  27. Unique somatic variants in DNA from urine exosomes of individuals with bladder cancer. Mol Ther Methods Clin Dev. 2021 Sep 10; 22:360-376.
    View in: PubMed
    Score: 0.196
  28. Therapeutic targeting of STAT3 with small interference RNAs and antisense oligonucleotides embedded exosomes in liver fibrosis. FASEB J. 2021 05; 35(5):e21557.
    View in: PubMed
    Score: 0.195
  29. Effective delivery of STING agonist using exosomes suppresses tumor growth and enhances antitumor immunity. J Biol Chem. 2021 Jan-Jun; 296:100523.
    View in: PubMed
    Score: 0.193
  30. Type I collagen deletion in aSMA+ myofibroblasts augments immune suppression and accelerates progression of pancreatic cancer. Cancer Cell. 2021 04 12; 39(4):548-565.e6.
    View in: PubMed
    Score: 0.193
  31. Protection against SARS-CoV-2 by BCG vaccination is not supported by epidemiological analyses. Sci Rep. 2020 10 27; 10(1):18377.
    View in: PubMed
    Score: 0.189
  32. Heterogeneous antibodies against SARS-CoV-2 spike receptor binding domain and nucleocapsid with implications for COVID-19 immunity. JCI Insight. 2020 09 17; 5(18).
    View in: PubMed
    Score: 0.187
  33. SIRT1 Regulates Lysosome Function and Exosome Secretion. Dev Cell. 2019 05 06; 49(3):302-303.
    View in: PubMed
    Score: 0.170
  34. Podoplanin+ tumor lymphatics are rate limiting for breast cancer metastasis. PLoS Biol. 2018 12; 16(12):e2005907.
    View in: PubMed
    Score: 0.166
  35. Loss of placental growth factor ameliorates maternal hypertension and preeclampsia in mice. J Clin Invest. 2018 11 01; 128(11):5008-5017.
    View in: PubMed
    Score: 0.164
  36. BMP7 Signaling in TGFBR2-Deficient Stromal Cells Provokes Epithelial Carcinogenesis. Mol Cancer Res. 2018 10; 16(10):1568-1578.
    View in: PubMed
    Score: 0.160
  37. Generation and testing of clinical-grade exosomes for pancreatic cancer. JCI Insight. 2018 04 19; 3(8).
    View in: PubMed
    Score: 0.158
  38. Spatial computation of intratumoral T cells correlates with survival of patients with pancreatic cancer. Nat Commun. 2017 04 27; 8:15095.
    View in: PubMed
    Score: 0.148
  39. Epithelial-to-mesenchymal transition is dispensable for metastasis but induces chemoresistance in pancreatic cancer. Nature. 2015 Nov 26; 527(7579):525-530.
    View in: PubMed
    Score: 0.134
  40. Thrombospondin-1 deficiency causes a shift from fibroproliferative to inflammatory kidney disease and delays onset of renal failure. Am J Pathol. 2014 Oct; 184(10):2687-98.
    View in: PubMed
    Score: 0.123
  41. Depletion of carcinoma-associated fibroblasts and fibrosis induces immunosuppression and accelerates pancreas cancer with reduced survival. Cancer Cell. 2014 Jun 16; 25(6):719-34.
    View in: PubMed
    Score: 0.121
  42. Identification of human epididymis protein-4 as a fibroblast-derived mediator of fibrosis. Nat Med. 2013 Feb; 19(2):227-31.
    View in: PubMed
    Score: 0.110
  43. Pericyte depletion results in hypoxia-associated epithelial-to-mesenchymal transition and metastasis mediated by met signaling pathway. Cancer Cell. 2012 Jan 17; 21(1):66-81.
    View in: PubMed
    Score: 0.103
  44. VEGF-A and Tenascin-C produced by S100A4+ stromal cells are important for metastatic colonization. Proc Natl Acad Sci U S A. 2011 Sep 20; 108(38):16002-7.
    View in: PubMed
    Score: 0.100
  45. Integrin beta1-mediated matrix assembly and signaling are critical for the normal development and function of the kidney glomerulus. Dev Biol. 2008 Jan 15; 313(2):584-93.
    View in: PubMed
    Score: 0.077
  46. BMP-7 functions as a novel hormone to facilitate liver regeneration. FASEB J. 2007 Jan; 21(1):256-64.
    View in: PubMed
    Score: 0.072
  47. Author Correction: Genotype tunes pancreatic ductal adenocarcinoma tissue tension to induce matricellular fibrosis and tumor progression. Nat Med. 2024 Mar; 30(3):908.
    View in: PubMed
    Score: 0.059
  48. Circulating ACE2-expressing extracellular vesicles block broad strains of SARS-CoV-2. Nat Commun. 2022 01 20; 13(1):405.
    View in: PubMed
    Score: 0.051
  49. aSMA+ fibroblasts suppress Lgr5+ cancer stem cells and restrain colorectal cancer progression. Oncogene. 2021 07; 40(26):4440-4452.
    View in: PubMed
    Score: 0.049
  50. Endothelial-to-mesenchymal transition compromises vascular integrity to induce Myc-mediated metabolic reprogramming in kidney fibrosis. Sci Signal. 2020 06 09; 13(635).
    View in: PubMed
    Score: 0.046
  51. Epigenetic Reprogramming of Cancer-Associated Fibroblasts Deregulates Glucose Metabolism and Facilitates Progression of Breast Cancer. Cell Rep. 2020 06 02; 31(9):107701.
    View in: PubMed
    Score: 0.046
  52. B cells and tertiary lymphoid structures promote immunotherapy response. Nature. 2020 01; 577(7791):549-555.
    View in: PubMed
    Score: 0.045
  53. Dual reporter genetic mouse models of pancreatic cancer identify an epithelial-to-mesenchymal transition-independent metastasis program. EMBO Mol Med. 2018 10; 10(10).
    View in: PubMed
    Score: 0.041
  54. Exosomes facilitate therapeutic targeting of oncogenic KRAS in pancreatic cancer. Nature. 2017 06 22; 546(7659):498-503.
    View in: PubMed
    Score: 0.037
  55. Detection of mutant KRAS and TP53 DNA in circulating exosomes from healthy individuals and patients with pancreatic cancer. Cancer Biol Ther. 2017 03 04; 18(3):158-165.
    View in: PubMed
    Score: 0.036
  56. Genotype tunes pancreatic ductal adenocarcinoma tissue tension to induce matricellular fibrosis and tumor progression. Nat Med. 2016 05; 22(5):497-505.
    View in: PubMed
    Score: 0.034
  57. Depletion of Carcinoma-Associated Fibroblasts and Fibrosis Induces Immunosuppression and Accelerates Pancreas Cancer with Reduced Survival. Cancer Cell. 2015 Dec 14; 28(6):831-833.
    View in: PubMed
    Score: 0.034
  58. Mass Spectrometry and Antibody-Based Characterization of Blood Vessels from Brachylophosaurus canadensis. J Proteome Res. 2015 Dec 04; 14(12):5252-62.
    View in: PubMed
    Score: 0.034
  59. Epithelial-to-mesenchymal transition induces cell cycle arrest and parenchymal damage in renal fibrosis. Nat Med. 2015 Sep; 21(9):998-1009.
    View in: PubMed
    Score: 0.033
  60. Glypican-1 identifies cancer exosomes and detects early pancreatic cancer. Nature. 2015 Jul 09; 523(7559):177-82.
    View in: PubMed
    Score: 0.033
  61. Targeting vascular pericytes in hypoxic tumors increases lung metastasis via angiopoietin-2. Cell Rep. 2015 Feb 24; 10(7):1066-81.
    View in: PubMed
    Score: 0.032
  62. Tet3-mediated hydroxymethylation of epigenetically silenced genes contributes to bone morphogenic protein 7-induced reversal of kidney fibrosis. J Am Soc Nephrol. 2014 May; 25(5):905-12.
    View in: PubMed
    Score: 0.030
  63. Reply to Regarding the mechanism of action of a proposed peptide agonist of the bone morphogenetic protein receptor activin-like kinase 3. Nat Med. 2013 Jul; 19(7):810-1.
    View in: PubMed
    Score: 0.028
  64. TGF-?1-containing exosomes from injured epithelial cells activate fibroblasts to initiate tissue regenerative responses and fibrosis. J Am Soc Nephrol. 2013 Feb; 24(3):385-92.
    View in: PubMed
    Score: 0.027
  65. Activin-like kinase 3 is important for kidney regeneration and reversal of fibrosis. Nat Med. 2012 Feb 05; 18(3):396-404.
    View in: PubMed
    Score: 0.026
  66. Exploiting cancer cell vulnerabilities to develop a combination therapy for ras-driven tumors. Cancer Cell. 2011 Sep 13; 20(3):400-13.
    View in: PubMed
    Score: 0.025
  67. Biomolecular characterization and protein sequences of the Campanian hadrosaur B. canadensis. Science. 2009 May 01; 324(5927):626-31.
    View in: PubMed
    Score: 0.021
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Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.