Connection

MACUS T KUO to Argininosuccinate Synthase

This is a "connection" page, showing publications MACUS T KUO has written about Argininosuccinate Synthase.
Connection Strength

3.065
  1. Chromatin remodeling system p300-HDAC2-Sin3A is involved in Arginine Starvation-Induced HIF-1a Degradation at the ASS1 promoter for ASS1 Derepression. Sci Rep. 2017 09 07; 7(1):10814.
    View in: PubMed
    Score: 0.606
  2. Cisplatin-induced synthetic lethality to arginine-starvation therapy by transcriptional suppression of ASS1 is regulated by DEC1, HIF-1a, and c-Myc transcription network and is independent of ASS1 promoter DNA methylation. Oncotarget. 2016 Dec 13; 7(50):82658-82670.
    View in: PubMed
    Score: 0.576
  3. Argininosuccinate synthetase 1 (ASS1) is a common metabolic marker of chemosensitivity for targeted arginine- and glutamine-starvation therapy. Cancer Lett. 2017 03 01; 388:54-63.
    View in: PubMed
    Score: 0.575
  4. Activation of Ras/PI3K/ERK pathway induces c-Myc stabilization to upregulate argininosuccinate synthetase, leading to arginine deiminase resistance in melanoma cells. Cancer Res. 2012 May 15; 72(10):2622-33.
    View in: PubMed
    Score: 0.416
  5. Resistance to arginine deiminase treatment in melanoma cells is associated with induced argininosuccinate synthetase expression involving c-Myc/HIF-1alpha/Sp4. Mol Cancer Ther. 2009 Dec; 8(12):3223-33.
    View in: PubMed
    Score: 0.354
  6. Arginine deprivation in cancer therapy. Curr Opin Clin Nutr Metab Care. 2015 Jan; 18(1):78-82.
    View in: PubMed
    Score: 0.126
  7. Arginine deiminase resistance in melanoma cells is associated with metabolic reprogramming, glucose dependence, and glutamine addiction. Mol Cancer Ther. 2013 Nov; 12(11):2581-90.
    View in: PubMed
    Score: 0.115
  8. Negative argininosuccinate synthetase expression in melanoma tumours may predict clinical benefit from arginine-depleting therapy with pegylated arginine deiminase. Br J Cancer. 2012 Apr 24; 106(9):1481-5.
    View in: PubMed
    Score: 0.104
  9. Targeted cellular metabolism for cancer chemotherapy with recombinant arginine-degrading enzymes. Oncotarget. 2010 Aug; 1(4):246-51.
    View in: PubMed
    Score: 0.093
  10. Targeting argininosuccinate synthetase negative melanomas using combination of arginine degrading enzyme and cisplatin. Oncotarget. 2015 Mar 20; 6(8):6295-309.
    View in: PubMed
    Score: 0.032
  11. The relationship of thioredoxin-1 and cisplatin resistance: its impact on ROS and oxidative metabolism in lung cancer cells. Mol Cancer Ther. 2012 Mar; 11(3):604-15.
    View in: PubMed
    Score: 0.026
  12. Arginine deprivation, autophagy, apoptosis (AAA) for the treatment of melanoma. Curr Mol Med. 2010 Jun; 10(4):405-12.
    View in: PubMed
    Score: 0.023
  13. Arginine deprivation as a targeted therapy for cancer. Curr Pharm Des. 2008; 14(11):1049-57.
    View in: PubMed
    Score: 0.019
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.