HELEN PIWNICA-WORMS to DNA Damage
This is a "connection" page, showing publications HELEN PIWNICA-WORMS has written about DNA Damage.
Connection Strength
1.326
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Fasting protects mice from lethal DNA damage by promoting small intestinal epithelial stem cell survival. Proc Natl Acad Sci U S A. 2015 Dec 22; 112(51):E7148-54.
Score: 0.298
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Synthetic lethality of Chk1 inhibition combined with p53 and/or p21 loss during a DNA damage response in normal and tumor cells. Oncogene. 2013 Jan 31; 32(5):577-88.
Score: 0.230
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The G(2) DNA damage checkpoint delays expression of genes encoding mitotic regulators. J Biol Chem. 2001 Oct 05; 276(40):37166-77.
Score: 0.110
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ATR-mediated checkpoint pathways regulate phosphorylation and activation of human Chk1. Mol Cell Biol. 2001 Jul; 21(13):4129-39.
Score: 0.110
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Poly(ADP-ribose)-binding promotes Exo1 damage recruitment and suppresses its nuclease activities. DNA Repair (Amst). 2015 Nov; 35:106-15.
Score: 0.074
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Targeting Chk1 in p53-deficient triple-negative breast cancer is therapeutically beneficial in human-in-mouse tumor models. J Clin Invest. 2012 Apr; 122(4):1541-52.
Score: 0.058
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Casein kinase 1 functions as both penultimate and ultimate kinase in regulating Cdc25A destruction. Oncogene. 2010 Jun 10; 29(23):3324-34.
Score: 0.050
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Regulation of Chk2 ubiquitination and signaling through autophosphorylation of serine 379. Mol Cell Biol. 2008 Oct; 28(19):5874-85.
Score: 0.045
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Gamma-herpesvirus kinase actively initiates a DNA damage response by inducing phosphorylation of H2AX to foster viral replication. Cell Host Microbe. 2007 Jun 14; 1(4):275-86.
Score: 0.041
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Normal cell cycle and checkpoint responses in mice and cells lacking Cdc25B and Cdc25C protein phosphatases. Mol Cell Biol. 2005 Apr; 25(7):2853-60.
Score: 0.036
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Comprehensive proteomic analysis of interphase and mitotic 14-3-3-binding proteins. J Biol Chem. 2004 Jul 30; 279(31):32046-54.
Score: 0.033
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Disruption of the checkpoint kinase 1/cell division cycle 25A pathway abrogates ionizing radiation-induced S and G2 checkpoints. Proc Natl Acad Sci U S A. 2002 Nov 12; 99(23):14795-800.
Score: 0.030
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The Chk1 protein kinase and the Cdc25C regulatory pathways are targets of the anticancer agent UCN-01. J Biol Chem. 2000 Feb 25; 275(8):5600-5.
Score: 0.025
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DNA damage and replication checkpoints in fission yeast require nuclear exclusion of the Cdc25 phosphatase via 14-3-3 binding. Mol Cell Biol. 1999 Nov; 19(11):7410-9.
Score: 0.024
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Cell cycle. Fools rush in. Nature. 1999 Oct 07; 401(6753):535, 537.
Score: 0.024
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Ca2+-Stimulated AMPK-Dependent Phosphorylation of Exo1 Protects Stressed Replication Forks from Aberrant Resection. Mol Cell. 2019 06 20; 74(6):1123-1137.e6.
Score: 0.024
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A human Cds1-related kinase that functions downstream of ATM protein in the cellular response to DNA damage. Proc Natl Acad Sci U S A. 1999 Mar 30; 96(7):3745-50.
Score: 0.023
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Conservation of the Chk1 checkpoint pathway in mammals: linkage of DNA damage to Cdk regulation through Cdc25. Science. 1997 Sep 05; 277(5331):1497-501.
Score: 0.021
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Mitotic and G2 checkpoint control: regulation of 14-3-3 protein binding by phosphorylation of Cdc25C on serine-216. Science. 1997 Sep 05; 277(5331):1501-5.
Score: 0.021
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Flap Endonuclease 1 Limits Telomere Fragility on the Leading Strand. J Biol Chem. 2015 Jun 12; 290(24):15133-45.
Score: 0.018
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Okazaki fragment processing-independent role for human Dna2 enzyme during DNA replication. J Biol Chem. 2012 Jun 22; 287(26):21980-91.
Score: 0.015
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Lack of PTEN sequesters CHK1 and initiates genetic instability. Cancer Cell. 2005 Feb; 7(2):193-204.
Score: 0.009
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Dual phosphorylation controls Cdc25 phosphatases and mitotic entry. Nat Cell Biol. 2003 Jun; 5(6):545-51.
Score: 0.008