HONGJIE LI

TitleAssistant Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Molecular & Human Genetics
AddressOne Baylor Plaza
Houston, TX 77030
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    Other Positions
    TitleAssistant Professor
    InstitutionBaylor College of Medicine
    DepartmentHuffington Center on Aging
    DivisionHuffington Ctr on Aging


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    Collapse education and training
    Stanford University, Stanford, CAPostdoc01/2021neurobiology, development
    University of Rochester, Rochester, NYPhD03/2016aging, stem cell, Drosophila
    University of Sci. Tech. of China (USTC), Hefei, ChinaBS07/2010Biology

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    K99AG062746     (LI, HONGJIE)Apr 1, 2019 - Mar 31, 2021
    NIH
    Characterizing the assembly and age-related decline of neural circuits in Drosophila by single-cell profiling
    Role: Principal Investigator

    RR200063     (LI, HONGJIE)Jan 4, 2021 - Jan 3, 2026
    Cancer Prevention and Research Institute of Texas (CPRIT)
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Task, D., Lin, C., Afify A., Li, H., Vulpe, A., Menuz, K., Potter, C.J. Widespread Polymodal Chemosensory Receptor Expression in Drosophila Olfactory Neurons. bioRxiv. 2020.
    2. Xie, Q., Brbic, M., Horns, F., Kolluru, S.S., Jones R.J., Li, J., Reddy, A., Xie, A., Kohani S., Li, Z., McLaughlin, C.N., Li, T., Xu, C., Vacek, D., Luginbuhl, D.J., Leskovec, J., Quake S.R., Luo, L., Li, H. . Temporal evolution of single-cell transcriptomes of Drosophila olfactory projection neurons. bioRxiv. 2020.
    3. McLaughlin, C.N., Brbic, M., Xie, Q., Li, T., Horns, F., Kolluru, S.S., Kebschull, J.M., Vacek, D., Xie, A., Li, J., Jones R.J., Leskovec, J., Quake S.R., Luo, L., Li, H. Single-cell transcriptomes of developing and adult olfactory receptor neurons in Drosophila. bioRxiv. 2020.
    4. Li H. Single-cell RNA sequencing in Drosophila: Technologies and applications. Wiley Interdiscip Rev Dev Biol. 2020 Sep 16; e396. PMID: 32940008.
      Citations: 4     Fields:    
    5. Wenderski W, Wang L, Krokhotin A, Walsh JJ, Li H, Shoji H, Ghosh S, George RD, Miller EL, Elias L, Gillespie MA, Son EY, Staahl BT, Baek ST, Stanley V, Moncada C, Shipony Z, Linker SB, Marchetto MCN, Gage FH, Chen D, Sultan T, Zaki MS, Ranish JA, Miyakawa T, Luo L, Malenka RC, Crabtree GR, Gleeson JG. Loss of the neural-specific BAF subunit ACTL6B relieves repression of early response genes and causes recessive autism. Proc Natl Acad Sci U S A. 2020 05 05; 117(18):10055-10066. PMID: 32312822.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    6. Li H, Li T, Horns F, Li J, Xie Q, Xu C, Wu B, Kebschull JM, McLaughlin CN, Kolluru SS, Jones RC, Vacek D, Xie A, Luginbuhl DJ, Quake SR, Luo L. Single-Cell Transcriptomes Reveal Diverse Regulatory Strategies for Olfactory Receptor Expression and Axon Targeting. Curr Biol. 2020 04 06; 30(7):1189-1198.e5. PMID: 32059767.
      Citations: 8     Fields:    
    7. Li J, Han S, Li H, Udeshi ND, Svinkina T, Mani DR, Xu C, Guajardo R, Xie Q, Li T, Luginbuhl DJ, Wu B, McLaughlin CN, Xie A, Kaewsapsak P, Quake SR, Carr SA, Ting AY, Luo L. Cell-Surface Proteomic Profiling in the Fly Brain Uncovers Wiring Regulators. Cell. 2020 01 23; 180(2):373-386.e15. PMID: 31955847.
      Citations: 16     Fields:    Translation:AnimalsCells
    8. Xie Q, Wu B, Li J, Xu C, Li H, Luginbuhl DJ, Wang X, Ward A, Luo L. Transsynaptic Fish-lips signaling prevents misconnections between nonsynaptic partner olfactory neurons. Proc Natl Acad Sci U S A. 2019 08 06; 116(32):16068-16073. PMID: 31341080.
      Citations: 7     Fields:    Translation:AnimalsCells
    9. Tracy Cai X, Li H, Safyan A, Gawlik J, Pyrowolakis G, Jasper H. AWD regulates timed activation of BMP signaling in intestinal stem cells to maintain tissue homeostasis. Nat Commun. 2019 07 05; 10(1):2988. PMID: 31278345.
      Citations: 1     Fields:    Translation:AnimalsCells
    10. Li J, Guajardo R, Xu C, Wu B, Li H, Li T, Luginbuhl DJ, Xie X, Luo L. Stepwise wiring of the Drosophila olfactory map requires specific Plexin B levels. Elife. 2018 08 23; 7. PMID: 30136927.
      Citations: 6     Fields:    Translation:AnimalsCells
    11. Li H, Shuster SA, Li J, Luo L. Linking neuronal lineage and wiring specificity. Neural Dev. 2018 04 13; 13(1):5. PMID: 29653548.
      Citations: 10     Fields:    Translation:AnimalsCells
    12. Li H, Horns F, Wu B, Xie Q, Li J, Li T, Luginbuhl DJ, Quake SR, Luo L. Classifying Drosophila Olfactory Projection Neuron Subtypes by Single-Cell RNA Sequencing. Cell. 2017 Nov 16; 171(5):1206-1220.e22. PMID: 29149607.
      Citations: 59     Fields:    Translation:AnimalsCells
    13. Li H, Qi Y, Jasper H. Ubx dynamically regulates Dpp signaling by repressing Dad expression during copper cell regeneration in the adult Drosophila midgut. Dev Biol. 2016 11 15; 419(2):373-381. PMID: 27570230.
      Citations: 4     Fields:    Translation:AnimalsCells
    14. Li H, Jasper H. Gastrointestinal stem cells in health and disease: from flies to humans. Dis Model Mech. 2016 05 01; 9(5):487-99. PMID: 27112333.
      Citations: 41     Fields:    Translation:HumansAnimalsCells
    15. Li H, Qi Y, Jasper H. Preventing Age-Related Decline of Gut Compartmentalization Limits Microbiota Dysbiosis and Extends Lifespan. Cell Host Microbe. 2016 Feb 10; 19(2):240-53. PMID: 26867182.
      Citations: 53     Translation:AnimalsCells
    16. Ayyaz A, Li H, Jasper H. Haemocytes control stem cell activity in the Drosophila intestine. Nat Cell Biol. 2015 Jun; 17(6):736-48. PMID: 26005834.
      Citations: 49     Fields:    Translation:AnimalsCells
    17. Li, H., and Wei, C. Diet, gut microbiota and obesity. J Nutrition Health Food Sci. 2015.
    18. Hine CM, Li H, Xie L, Mao Z, Seluanov A, Gorbunova V. Regulation of Rad51 promoter. Cell Cycle. 2014; 13(13):2038-45. PMID: 24781030.
      Citations: 8     Translation:HumansCells
    19. Li H, Qi Y, Jasper H. Dpp signaling determines regional stem cell identity in the regenerating adult Drosophila gastrointestinal tract. Cell Rep. 2013 Jul 11; 4(1):10-8. PMID: 23810561.
      Citations: 37     Fields:    Translation:AnimalsCells
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