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TRAN LOCKE

TitleAssistant Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Otolaryngology-Head and Neck Surgery
Address1977 BUTLER BOULEVARD
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    Collapse Biography 
    Collapse education and training
    Brown University, Providence, RIBS05/2009Biology
    McGovern Medical School, Houston, TXMD05/2014
    University of Kansas School of Medicine, Kansas City, KS06/2019Otolaryngology
    University of Pennsylvania, Philadelphia, PA06/2020Rhinology & Anterior Skull Base Surgery
    Collapse awards and honors
    2013Alpha Omega Alpha Honor Medical Society, McGovern Medical School
    2014Dierks Surgical Scholarship, McGovern Medical School
    2018AAO-HNS/SRF Resident Leadership Grant

    Collapse Overview 
    Collapse overview
    Dr. Locke is an assistant professor in the Department of Otolaryngology – Head and Neck
    Surgery and a fellowship-trained rhinologist and anterior skull base surgeon. Her surgical
    practice is focused on inflammatory sinus disease, benign and malignant sinonasal and skull
    base tumors, and repair of cerebrospinal fluid leaks. She has a special interest in revision sinus
    surgery, particularly for challenging frontal and sphenoid sinus work. Her research interests center
    around allergy, health informatics, and quality of life outcomes for chronic rhinosinusitis and
    sinonasal tumors. She is passionate about providing high-quality, personalized medical and
    surgical care to patients with diseases of the nose and sinuses.

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    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Nguyen TV, Abiri A, Idowu V, Patel S, Truong T, Lerner DK, Workman AD, Batra PS, Campbell RG, Craig JR, Crosby DL, Douglas JE, Eide JG, Kohanski MA, Kshirsagar RS, Locke TB, Papagiannopoulos P, Tajudeen BA, Tong CCL, Adappa ND, Palmer JN, Kuan EC. Outcomes of Autologous versus Synthetic Inlay Grafts After Skull Base Reconstruction for High-Flow Defects: A Multicenter Case-Control Analysis. Int Forum Allergy Rhinol. 2025 Apr; 15(4):441-444. PMID: 39740087; PMCID: PMC11970444.
      Citations:    Fields:    
    2. Eide JG, Kuan EC, Adappa ND, Chang J, Cho DY, Garg R, Govindaraj S, Grayson J, Im E, Keschner D, Kohanski M, Locke T, Palmer JN, Welch KC, Woodworth BA, Yoo F, Craig JR. Subtotal Middle Turbinate Resection in Patients with Chronic Rhinosinusitis with Nasal Polyps is Unlikely to Cause Empty Nose Syndrome: A Multi-Institutional Prospective Study. Laryngoscope. 2025 01; 135(1):59-65. PMID: 39136246.
      Citations:    Fields:    Translation:Humans
    3. Antognoni P, Bernal-Sprekelsen M, Betz CS, Blay JY, Castelnuovo P, Chatzinakis V, Dallan I, Dassi CS, Lund VJ, Huang Z, Huang Z, Kuo YJ, Lechner M, Lee VH, Lin JC, Matnjani G, Nicolai P, Otori N, Schafhausen P, Stamm A, St?lzel K, Surda P, Tsang RK, Turri-Zanoni M, Wong SN, Kuan EC, Wang EW, Adappa ND, Beswick DM, London NR, Su SY, Wang MB, Abuzeid WM, Alexiev B, Alt JA, Alonso-Basanta M, Batra PS, Bhayani M, Bell D, Bleier BS, Bonilla-Velez J, Callejas C, Carrau RL, Casiano RR, Chandra RK, Chen SB, Chiu AG, Choby G, Chowdhury NI, Citardi MJ, Cohen MA, Dagan R, Dalfino G, de Almeida J, Dei Tos AP, DelGaudio JM, Ebert CS, El-Sayed IH, Eloy JA, Evans JJ, Fang CH, Farrell NF, Ferrari M, Fischbein N, Folbe A, Fokkens WJ, Fox MG, Gallia GL, Gardner PA, Geltzeiler M, Georgalas C, Getz AE, Govindaraj S, Gray ST, Grayson JW, Gross BA, Grube JG, Guo R, Ha PK, Halderman AA, Hanna EY, Harvey RJ, Hernandez SC, Holtzman AL, Hopkins C, Humphreys IM, Hwang PH, Iloreta AM, Ishii M, Ivan ME, Jafari A, Kennedy DW, Khan M, Kimple AJ, Kingdom TT, Knisely A, Lal D, Lamarre ED, Lan MY, Le H, Lee NY, Lee JK, Levine CG, Lin DT, Lobo BC, Locke T, Luong AU, Magliocca KR, Markovic SN, McKean EL, Me?o C, Mendenhall WM, Michel L, Na'ara S, Nuss DW, Nyquist GG, Oakley GM, Omura K, Orlandi RR, Papagiannopoulos P, Patel ZM, Pfister DG, Phan J, Psaltis AJ, Rabinowitz MR, Ramanathan M, Rimmer R, Rosen MR, Sanusi O, Sargi ZB, Schlosser RJ, Sedaghat AR, Senior BA, Shrivastava R, Sindwani R, Smith TL, Smith KA, Snyderman CH, Solares CA, Sreenath SB, Sumer B, Tajudeen BA, Thompson LDR, Thorp BD, Tong CCL, Turner JH, Udager AM, van Zele T, VanKoevering K, Welch KC, Wise SK, Witterick IJ, Won TB, Woodworth BA, Wormald PJ, Yao WC, Yeh CF, Zhou B, Palmer JN. International Consensus Statement on Allergy and Rhinology: Sinonasal Tumors. Int Forum Allergy Rhinol. 2024 Feb; 14(2):149-608. PMID: 37658764.
      Citations: 1     Fields:    Translation:Humans
    4. Salmon MK, Kshirsagar RS, Eide JG, Sweis AM, Davin K, Prasad A, Ungerer H, Stevens E, Ig-Izevbekhai K, Tripathi S, Locke TB, Lin T, Sweis BM, Kohanski MA, Adappa ND, Palmer JN. Postoperative mometasone irrigations improve quality of life in skull base tumor patients. World J Otorhinolaryngol Head Neck Surg. 2023 Dec; 9(4):314-319. PMID: 38059136; PMCID: PMC10696264.
      Citations:    
    5. Saleh S, Sullivan SE, Bellile E, Roxbury C, Das P, Hachem RA, Ackall F, Jang D, Celtikci E, Sahin MM, D'souza G, Evans JJ, Nyquist G, Khalafallah A, Mukherjee D, Rowan NR, Camp S, Choby G, Gompel JJV, Ghiam MK, Levine CG, Field M, Adappa N, Locke TB, Rassekh C, Sweis AM, Goyal N, Zacharia B, Wilson MN, Patel S, Gardner PA, Snyderman CH, Wang EW, Glancz LJ, Bagchi A, Dow G, Robertson I, Rangarajan SV, Michael LM, McKean EL. Retrospective Review of Surgical Site Infections after Endoscopic Endonasal Sellar and Parasellar Surgery: Multicenter Quality Data from the North American Skull Base Society. J Neurol Surg B Skull Base. 2022 Dec; 83(6):579-588. PMID: 36393885; PMCID: PMC9653291.
      Citations:    
    6. Eide JG, Salmon MK, Kshirsagar RS, Patel TD, Davin KM, Prasad A, Stevens EM, Ungerer H, Sweis AM, Locke TB, Lee JY, Grady MS, Yoshor D, Storm PB, Adappa ND, Palmer JN. Reconstruction with Mucosal Graft Reduces Recurrence After Endoscopic Surgery of Rathke Cleft Cyst. World Neurosurg. 2022 11; 167:e664-e669. PMID: 36028104.
      Citations:    
    7. Vohra V, Watley DC, Yan CH, Locke TB, Bernstein IA, Levy JM, Rowan NR. Predictors of academic career placement and scholarly impact in fellowship-trained rhinologists. Int Forum Allergy Rhinol. 2022 01; 12(1):62-70. PMID: 34309228.
      Citations:    Fields:    Translation:Humans
    8. Locke TB, Sweis AM, Douglas JE, Ig-Izevbekhai KI, Stevens EM, Civantos AM, McCarty EB, Kumar A, Kohanski MA, Kennedy DW, Palmer JN, Bosso JV, Adappa ND. Treatment Outcomes in Aspirin-Exacerbated Respiratory Disease Based on the 12-Item Short Form Survey. Am J Rhinol Allergy. 2021 Nov; 35(6):790-797. PMID: 33691498.
      Citations:    Fields:    Translation:Humans
    9. Sweis AM, Locke TB, Ig-Izevbekhai KI, Lin TC, Kumar A, Douglas JE, Corr AM, Civantos AM, Tripathi SH, Kennedy DW, Kohanski MA, Palmer JN, Adappa ND, Bosso JV. Effectiveness of endoscopic sinus surgery and aspirin therapy in the management of aspirin-exacerbated respiratory disease. Allergy Asthma Proc. 2021 03 01; 42(2):136-141. PMID: 33685558; PMCID: PMC8133012.
      Citations: 1     Fields:    Translation:Humans
    10. Locke T, Sweis A, Lin T, Sweis B, Gleeson P, Kohanski M, Adappa N, Palmer J, Bosso J. The impact of endoscopic sinus surgery and aspirin desensitization on psychological burden in aspirin-exacerbated respiratory disease. World J Otorhinolaryngol Head Neck Surg. 2020 Dec; 6(4):214-219. PMID: 33336176; PMCID: PMC7729229.
      Citations:    
    11. Douglas J, Civantos A, LOCKE T, et al. Impact of Novel CFTR Modulator on Sinonasal Quality of Life in Adult Patients with Cystic Fibrosis. Int Forum Allergy Rhinol. 2020.
    12. LOCKE T, Sweis A, Lin T, et al. The Impact of Endoscopic Sinus Surgery and Aspirin Desensitization on Psychological Burden in Aspirin-Exacerbated Respiratory Disease. World Journal of Otorhinolaryngology-Head and Neck Surgery. 2020.
    13. Locke TB, Sweis AM, Gleeson PK, Lin TC, Civantos AM, Parhar HS, Corr AM, Kumar A, Salmon MK, Kohanski MA, Palmer JN, Bosso JV, Adappa ND. Age as a factor in treatment of aspirin-exacerbated respiratory disease: relationship to required aspirin maintenance dose after desensitization. Int Forum Allergy Rhinol. 2020 10; 10(10):1180-1181. PMID: 32761891.
      Citations:    Fields:    Translation:Humans
    14. Sweis AM, Locke TB, Ig-Izevbekhai KI, Lin TC, Gleeson PK, Civantos AM, Kumar A, Corr AM, Kohanski MA, Palmer JN, Bosso JV, Adappa ND. Major complications of aspirin desensitization and maintenance therapy in aspirin-exacerbated respiratory disease. Int Forum Allergy Rhinol. 2021 02; 11(2):115-119. PMID: 32671928.
      Citations: 2     Fields:    Translation:Humans
    15. Sweis AM, Locke TB, Douglas JE, Lin TC, Sweis BM, Civantos AM, Kennedy DW. Management of chronic rhinosinusitis with steroid nasal irrigations: A viable nonsurgical alternative in the COVID-19 era. Int Forum Allergy Rhinol. 2020 09; 10(9):1108-1109. PMID: 32573106; PMCID: PMC7361584.
      Citations: 1     Fields:    Translation:HumansCellsPHPublic Health
    16. Bosso JV, Locke TB, Kuan EC, Tripathi SH, Ig-Izevbekhai KI, Kalaf LT, Kohanski MA, Palmer JN, Adappa ND. Complete endoscopic sinus surgery followed by aspirin desensitization is associated with decreased overall corticosteroid use. Int Forum Allergy Rhinol. 2020 09; 10(9):1043-1048. PMID: 32558306.
      Citations: 3     Fields:    Translation:Humans
    17. Atypical Presentation of Pyomyositis in a Young Immunocompetent Male with History of Prior Neck Trauma: a case report. J Otolaryngol ENT Res. 2018; 5(10):285-287.
    18. . Inhibition of fibroblast growth factor receptor with AZD4547 mitigates juvenile nasopharyngeal angiofibroma. Int Forum Allergy Rhinol. 2018; 10(7):973-979.
    19. . PPAR Agonist Rescue of Ethanol-Impaired Brain Insulin/IGF Signaling Impairments Following Developmental Exposure to Alcohol. J Drug Alc Res. 2012; (2).
    20. . Impaired Insulin/IGF Signaling in Experimental Alcohol-Related Myopathy. Nutrients. 2012; 8(4):1042-57.
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