TEJ PANDITA

TitleAdjunct Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Molecular & Cellular Biology
Address
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    Other Positions
    TitleAdjunct Professor
    InstitutionBaylor College of Medicine
    DepartmentCenter for Precision Environmental Health
    DivisionCenter for Precision Env Health


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    R01NS034746     (PANDITA, TEJ K)Jun 1, 1996 - Aug 31, 2007
    NIH
    CHROMATIN-TELOMERE STRUCTURE AND AT GENOMIC SENSITIVITY
    Role: Principal Investigator

    R13CA130756     (PANDITA, TEJ K.)Jul 3, 2007 - Jun 30, 2013
    NIH
    CHROMATIN STRUCTURE AND DNA REPAIR
    Role: Principal Investigator

    R01CA123232     (PANDITA, TEJ K.)Sep 1, 2007 - Jul 31, 2012
    NIH
    Functional Characterization of the Mammalian MOF Gene Product
    Role: Principal Investigator

    R01CA129537     (PANDITA, TEJ K)Sep 1, 2008 - Jun 30, 2021
    NIH
    Chromatin modifying factors control radiation response and genomic stability
    Role: Principal Investigator

    R01CA154320     (PANDITA, TEJ K)Sep 1, 2010 - Jul 31, 2016
    NIH
    Tumor-cell-specific targets for combined hyperthermia and radiation effects
    Role: Principal Investigator

    R13NS077719     (PANDITA, TEJ K.)Sep 30, 2011 - Aug 31, 2013
    NIH
    15th International Workshop on Ataxia-Telangiectasia and ATM to be held in India
    Role: Principal Investigator

    R01GM109768     (PANDITA, TEJ K)Jul 16, 2014 - Jun 30, 2020
    NIH
    Role of Heterochromatin protein 1 Beta in Genome Maintenance and Oncogenesis
    Role: Principal Investigator

    R13NS108700     (PANDITA, TEJ K)Aug 1, 2018 - Jul 31, 2019
    NIH
    18th International Workshop on Ataxia-Telangiectasia and ATM to be held at The Houston Methodist Research Institute
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Hebert KA, Jaramillo S, Yu W, Wang M, Veeramachaneni R, Sandulache VC, Sikora AG, Bonnen MD, Annapragada AV, Corry D, Kheradmand F, Pandita RK, Ludwig MS, Pandita TK, Huang S, Coarfa C, Grimm SL, Perera D, Miles G, Ghebre YT. Esomeprazole enhances the effect of ionizing radiation to improve tumor control. Oncotarget. 2021 Jul 06; 12(14):1339-1353. PMID: 34262645.
      Citations:    Fields:    
    2. Hambarde S, Tsai CL, Pandita RK, Bacolla A, Maitra A, Charaka V, Hunt CR, Kumar R, Limbo O, Le Meur R, Chazin WJ, Tsutakawa SE, Russell P, Schlacher K, Pandita TK, Tainer JA. EXO5-DNA structure and BLM interactions direct DNA resection critical for ATR-dependent replication restart. Mol Cell. 2021 Jul 15; 81(14):2989-3006.e9. PMID: 34197737.
      Citations:    Fields:    
    3. Mushtaq A, Mir US, Hunt CR, Pandita S, Tantray WW, Bhat A, Pandita RK, Altaf M, Pandita TK. Role of Histone Methylation in Maintenance of Genome Integrity. Genes (Basel). 2021 Jun 29; 12(7). PMID: 34209979.
      Citations:    Fields:    
    4. Banday S, Pandita RK, Mushtaq A, Bacolla A, Mir US, Singh DK, Jan S, Bhat KP, Hunt CR, Rao G, Charaka VK, Tainer JA, Pandita TK, Altaf M. Autism-Associated Vigilin Depletion Impairs DNA Damage Repair. Mol Cell Biol. 2021 06 23; 41(7):e0008221. PMID: 33941620.
      Citations:    Fields:    Translation:HumansCells
    5. Sarkar A, Stellrecht CM, Vangapandu HV, Ayres M, Kaipparettu BA, Park JH, Balakrishnan K, Burks JK, Pandita TK, Hittelman WN, Neelapu SS, Gandhi V. Ataxia-telangiectasia mutated interacts with Parkin and induces mitophagy independent of kinase activity. Evidence from mantle cell lymphoma. Haematologica. 2021 02 01; 106(2):495-512. PMID: 32029507.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    6. Singh M, Bacolla A, Chaudhary S, Hunt CR, Pandita S, Chauhan R, Gupta A, Tainer JA, Pandita TK. Histone Acetyltransferase MOF Orchestrates Outcomes at the Crossroad of Oncogenesis, DNA Damage Response, Proliferation, and Stem Cell Development. Mol Cell Biol. 2020 08 28; 40(18). PMID: 32661120.
      Citations:    Fields:    Translation:HumansCells
    7. Charaka V, Tiwari A, Pandita RK, Hunt CR, Pandita TK. Role of HP1ß during spermatogenesis and DNA replication. Chromosoma. 2020 12; 129(3-4):215-226. PMID: 32651609.
      Citations: 1     Fields:    
    8. Li L, Ghorbani M, Weisz-Hubshman M, Rousseau J, Thiffault I, Schnur RE, Breen C, Oegema R, Weiss MM, Waisfisz Q, Welner S, Kingston H, Hills JA, Boon EM, Basel-Salmon L, Konen O, Goldberg-Stern H, Bazak L, Tzur S, Jin J, Bi X, Bruccoleri M, McWalter K, Cho MT, Scarano M, Schaefer GB, Brooks SS, Hughes SS, van Gassen KLI, van Hagen JM, Pandita TK, Agrawal PB, Campeau PM, Yang XJ. Lysine acetyltransferase 8 is involved in cerebral development and syndromic intellectual disability. J Clin Invest. 2020 03 02; 130(3):1431-1445. PMID: 31794431.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    9. Shah R, Khaitan PG, Pandita TK, Rafiq A, Abrol D, Suri J, Kaul S, Kumar R, Sharma S. Gastric cancer in Jammu and Kashmir, India: A review of genetic perspectives. J Cancer Res Ther. 2020 Jan 27. PMID: 33533734.
      Citations:    Fields:    
    10. Hunt CR, Pandita TK. "What's Past is Prologue": Pre-Existing Epigenetic Transcriptional Marks May Also Influence DNA Repair Pathway Choice. Radiat Res. 2019 12; 192(6):577-578. PMID: 31634055.
      Citations: 1     Fields:    Translation:HumansCells
    11. Mays CE, Armijo E, Morales R, Kramm C, Flores A, Tiwari A, Bian J, Telling GC, Pandita TK, Hunt CR, Soto C. Prion disease is accelerated in mice lacking stress-induced heat shock protein 70 (HSP70). J Biol Chem. 2019 09 13; 294(37):13619-13628. PMID: 31320473.
      Citations: 9     Fields:    Translation:AnimalsCells
    12. Horikoshi N, Sharma D, Leonard F, Pandita RK, Charaka VK, Hambarde S, Horikoshi NT, Gaur Khaitan P, Chakraborty S, Cote J, Godin B, Hunt CR, Pandita TK. Pre-existing H4K16ac levels in euchromatin drive DNA repair by homologous recombination in S-phase. Commun Biol. 2019; 2:253. PMID: 31286070.
      Citations: 4     Translation:HumansCells
    13. Ge C, Vilfranc CL, Che L, Pandita RK, Hambarde S, Andreassen PR, Niu L, Olowokure O, Shah S, Waltz SE, Zou L, Wang J, Pandita TK, Du C. The BRUCE-ATR Signaling Axis Is Required for Accurate DNA Replication and Suppression of Liver Cancer Development. Hepatology. 2019 06; 69(6):2608-2622. PMID: 30693543.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    14. Yin H, Ma H, Hussain S, Zhang H, Xie X, Jiang L, Jiang X, Iqbal F, Bukhari I, Jiang H, Ali A, Zhong L, Li T, Fan S, Zhang B, Gao J, Li Y, Nazish J, Khan T, Khan M, Zubair M, Hao Q, Fang H, Huang J, Huleihel M, Sha J, Pandita TK, Zhang Y, Shi Q. Correction: A homozygous FANCM frameshift pathogenic variant causes male infertility. Genet Med. 2019 01; 21(1):266. PMID: 30158692.
      Citations:    Fields:    
    15. von Rüden EL, Wolf F, Gualtieri F, Keck M, Hunt CR, Pandita TK, Potschka H. Genetic and Pharmacological Targeting of Heat Shock Protein 70 in the Mouse Amygdala-Kindling Model. ACS Chem Neurosci. 2019 03 20; 10(3):1434-1444. PMID: 30396268.
      Citations: 1     Fields:    Translation:Animals
    16. Breed ER, Hilliard CA, Yoseph B, Mittal R, Liang Z, Chen CW, Burd EM, Brewster LP, Hansen LM, Gleason RL, Pandita TK, Ford ML, Hunt CR, Coopersmith CM. The small heat shock protein HSPB1 protects mice from sepsis. Sci Rep. 2018 08 21; 8(1):12493. PMID: 30131526.
      Citations: 2     Fields:    Translation:AnimalsCells
    17. Qin Q, Nan X, Miller T, Fisher R, Teh B, Pandita S, Farach AM, Pingali SR, Pandita RK, Butler EB, Pandita TK, Iyer SP. Complete Local and Abscopal Responses from a Combination of Radiation and Nivolumab in Refractory Hodgkin's Lymphoma. Radiat Res. 2018 09; 190(3):322-329. PMID: 29949442.
      Citations: 14     Fields:    Translation:Humans
    18. Yin H, Ma H, Hussain S, Zhang H, Xie X, Jiang L, Jiang X, Iqbal F, Bukhari I, Jiang H, Ali A, Zhong L, Li T, Fan S, Zhang B, Gao J, Li Y, Nazish J, Khan T, Khan M, Zubair M, Hao Q, Fang H, Huang J, Huleihel M, Sha J, Pandita TK, Zhang Y, Shi Q. A homozygous FANCM frameshift pathogenic variant causes male infertility. Genet Med. 2019 01; 21(1):62-70. PMID: 29895858.
      Citations: 16     Fields:    Translation:HumansAnimals
    19. Jiang H, Gao Q, Zheng W, Yin S, Wang L, Zhong L, Ali A, Khan T, Hao Q, Fang H, Sun X, Xu P, Pandita TK, Jiang X, Shi Q. MOF influences meiotic expansion of H2AX phosphorylation and spermatogenesis in mice. PLoS Genet. 2018 05; 14(5):e1007300. PMID: 29795555.
      Citations: 5     Fields:    Translation:AnimalsCells
    20. Chakraborty S, Pandita RK, Hambarde S, Mattoo AR, Charaka V, Ahmed KM, Iyer SP, Hunt CR, Pandita TK. SMARCAD1 Phosphorylation and Ubiquitination Are Required for Resection during DNA Double-Strand Break Repair. iScience. 2018 04 27; 2:123-135. PMID: 29888761.
      Citations: 12     
    21. Ahmed KM, Pandita RK, Singh DK, Hunt CR, Pandita TK. ß1-Integrin Impacts Rad51 Stability and DNA Double-Strand Break Repair by Homologous Recombination. Mol Cell Biol. 2018 05 01; 38(9). PMID: 29463647.
      Citations: 11     Fields:    Translation:HumansCells
    22. Mujoo K, Hunt CR, Pandita RK, Ferrari M, Krishnan S, Cooke JP, Hahn S, Pandita TK. Harnessing and Optimizing the Interplay between Immunotherapy and Radiotherapy to Improve Survival Outcomes. Mol Cancer Res. 2018 08; 16(8):1209-1214. PMID: 29592896.
      Citations: 5     Fields:    Translation:Humans
    23. Singh DK, Pandita RK, Singh M, Chakraborty S, Hambarde S, Ramnarain D, Charaka V, Ahmed KM, Hunt CR, Pandita TK. MOF Suppresses Replication Stress and Contributes to Resolution of Stalled Replication Forks. Mol Cell Biol. 2018 03 15; 38(6). PMID: 29298824.
      Citations: 4     Fields:    Translation:HumansCells
    24. Iyer SP, Hunt CR, Pandita TK. Cross Talk between Radiation and Immunotherapy: The Twain Shall Meet. Radiat Res. 2018 03; 189(3):219-224. PMID: 29261410.
      Citations: 4     Fields:    Translation:HumansAnimals
    25. Gadhikar MA, Zhang J, Shen L, Rao X, Wang J, Zhao M, Kalu NN, Johnson FM, Byers LA, Heymach J, Hittelman WN, Udayakumar D, Pandita RK, Pandita TK, Pickering CR, Redwood AB, Piwnica-Worms H, Schlacher K, Frederick MJ, Myers JN. CDKN2A/p16 Deletion in Head and Neck Cancer Cells Is Associated with CDK2 Activation, Replication Stress, and Vulnerability to CHK1 Inhibition. Cancer Res. 2018 02 01; 78(3):781-797. PMID: 29229598.
      Citations: 13     Fields:    Translation:HumansCells
    26. Goltsov AA, Fang B, Pandita TK, Maru DM, Swisher SG, Hofstetter WL. HER2 Confers Resistance to Foretinib Inhibition of MET-Amplified Esophageal Adenocarcinoma Cells. Ann Thorac Surg. 2018 Feb; 105(2):363-370. PMID: 29223420.
      Citations: 3     Fields:    Translation:HumansCells
    27. Mujoo K, Pandita RK, Tiwari A, Charaka V, Chakraborty S, Singh DK, Hambarde S, Hittelman WN, Horikoshi N, Hunt CR, Khanna KK, Kots AY, Butler EB, Murad F, Pandita TK. Differentiation of Human Induced Pluripotent or Embryonic Stem Cells Decreases the DNA Damage Repair by Homologous Recombination. Stem Cell Reports. 2017 11 14; 9(5):1660-1674. PMID: 29103969.
      Citations: 11     Fields:    Translation:HumansCells
    28. Patel N, Garikapati KR, Pandita RK, Singh DK, Pandita TK, Bhadra U, Bhadra MP. Erratum: miR-15a/miR-16 down-regulates BMI1, impacting Ub-H2A mediated DNA repair and breast cancer cell sensitivity to doxorubicin. Sci Rep. 2017 10 10; 7(1):12932. PMID: 29018209.
      Citations: 1     Fields:    
    29. Hussain T, Saha D, Purohit G, Kar A, Kishore Mukherjee A, Sharma S, Sengupta S, Dhapola P, Maji B, Vedagopuram S, Horikoshi NT, Horikoshi N, Pandita RK, Bhattacharya S, Bajaj A, Riou JF, Pandita TK, Chowdhury S. Transcription regulation of CDKN1A (p21/CIP1/WAF1) by TRF2 is epigenetically controlled through the REST repressor complex. Sci Rep. 2017 09 14; 7(1):11541. PMID: 28912501.
      Citations: 18     Fields:    Translation:HumansCells
    30. Wang H, Peng B, Pandita RK, Engler DA, Matsunami RK, Xu X, Hegde PM, Butler BE, Pandita TK, Mitra S, Xu B, Hegde ML. Aurora kinase B dependent phosphorylation of 53BP1 is required for resolving merotelic kinetochore-microtubule attachment errors during mitosis. Oncotarget. 2017 Jul 25; 8(30):48671-48687. PMID: 28415769.
      Citations: 3     Fields:    Translation:HumansCells
    31. Patel N, Garikapati KR, Pandita RK, Singh DK, Pandita TK, Bhadra U, Bhadra MP. miR-15a/miR-16 down-regulates BMI1, impacting Ub-H2A mediated DNA repair and breast cancer cell sensitivity to doxorubicin. Sci Rep. 2017 06 27; 7(1):4263. PMID: 28655885.
      Citations: 7     Fields:    
    32. Yin S, Jiang X, Jiang H, Gao Q, Wang F, Fan S, Khan T, Jabeen N, Khan M, Ali A, Xu P, Pandita TK, Fan HY, Zhang Y, Shi Q. Histone acetyltransferase KAT8 is essential for mouse oocyte development by regulating reactive oxygen species levels. Development. 2017 06 15; 144(12):2165-2174. PMID: 28506985.
      Citations: 10     Fields:    Translation:AnimalsCells
    33. Shi W, Vu T, Boucher D, Biernacka A, Nde J, Pandita RK, Straube J, Boyle GM, Al-Ejeh F, Nag P, Jeffery J, Harris JL, Bain AL, Grzelak M, Skrzypczak M, Mitra A, Dojer N, Crosetto N, Cloonan N, Becherel OJ, Finnie J, Skaar JR, Walkley CR, Pandita TK, Rowicka M, Ginalski K, Lane SW, Khanna KK. Ssb1 and Ssb2 cooperate to regulate mouse hematopoietic stem and progenitor cells by resolving replicative stress. Blood. 2017 05 04; 129(18):2479-2492. PMID: 28270450.
      Citations: 9     Fields:    Translation:AnimalsCells
    34. Valerio DG, Xu H, Chen CW, Hoshii T, Eisold ME, Delaney C, Cusan M, Deshpande AJ, Huang CH, Lujambio A, Zheng YG, Zuber J, Pandita TK, Lowe SW, Armstrong SA. Histone Acetyltransferase Activity of MOF Is Required for MLL-AF9 Leukemogenesis. Cancer Res. 2017 04 01; 77(7):1753-1762. PMID: 28202522.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    35. Mattoo AR, Pandita RK, Chakraborty S, Charaka V, Mujoo K, Hunt CR, Pandita TK. MCL-1 Depletion Impairs DNA Double-Strand Break Repair and Reinitiation of Stalled DNA Replication Forks. Mol Cell Biol. 2017 02 01; 37(3). PMID: 27821478.
      Citations: 14     Fields:    Translation:HumansCells
    36. Mujoo K, Hunt CR, Pandita TK. Nuclear functions of ß2-Spectrin in genomic stability. Aging (Albany NY). 2016 12 14; 8(12):3151-3152. PMID: 27978509.
      Citations:    Fields:    Translation:HumansAnimalsCells
    37. Pandita TK. Critical role of the POT1 OB domain in maintaining genomic stability. Oncogene. 2017 04 06; 36(14):1908-1910. PMID: 27869169.
      Citations: 1     Fields:    Translation:AnimalsCells
    38. Valerio DG, Xu H, Eisold ME, Woolthuis CM, Pandita TK, Armstrong SA. Histone acetyltransferase activity of MOF is required for adult but not early fetal hematopoiesis in mice. Blood. 2017 01 05; 129(1):48-59. PMID: 27827827.
      Citations: 13     Fields:    Translation:AnimalsCells
    39. Chakraborty A, Tapryal N, Venkova T, Horikoshi N, Pandita RK, Sarker AH, Sarkar PS, Pandita TK, Hazra TK. Classical non-homologous end-joining pathway utilizes nascent RNA for error-free double-strand break repair of transcribed genes. Nat Commun. 2016 10 05; 7:13049. PMID: 27703167.
      Citations: 54     Fields:    Translation:HumansCells
    40. Gaur P, Hunt CR, Pandita TK. Emerging therapeutic targets in esophageal adenocarcinoma. Oncotarget. 2016 Jul 26; 7(30):48644-48655. PMID: 27102294.
      Citations: 4     Fields:    Translation:HumansCells
    41. Mujoo K, Butler EB, Pandita RK, Hunt CR, Pandita TK. Pluripotent Stem Cells and DNA Damage Response to Ionizing Radiations. Radiat Res. 2016 07; 186(1):17-26. PMID: 27332952.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    42. Sadik H, Korangath P, Nguyen NK, Gyorffy B, Kumar R, Hedayati M, Teo WW, Park S, Panday H, Munoz TG, Menyhart O, Shah N, Pandita RK, Chang JC, DeWeese T, Chang HY, Pandita TK, Sukumar S. HOXC10 Expression Supports the Development of Chemotherapy Resistance by Fine Tuning DNA Repair in Breast Cancer Cells. Cancer Res. 2016 08 01; 76(15):4443-56. PMID: 27302171.
      Citations: 18     Fields:    Translation:HumansCells
    43. Horikoshi N, Pandita RK, Mujoo K, Hambarde S, Sharma D, Mattoo AR, Chakraborty S, Charaka V, Hunt CR, Pandita TK. ß2-spectrin depletion impairs DNA damage repair. Oncotarget. 2016 Jun 07; 7(23):33557-70. PMID: 27248179.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    44. Deb P, Bhan A, Hussain I, Ansari KI, Bobzean SA, Pandita TK, Perrotti LI, Mandal SS. Endocrine disrupting chemical, bisphenol-A, induces breast cancer associated gene HOXB9 expression in vitro and in vivo. Gene. 2016 Sep 30; 590(2):234-43. PMID: 27182052.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    45. Jacquet K, Fradet-Turcotte A, Avvakumov N, Lambert JP, Roques C, Pandita RK, Paquet E, Herst P, Gingras AC, Pandita TK, Legube G, Doyon Y, Durocher D, Côté J. The TIP60 Complex Regulates Bivalent Chromatin Recognition by 53BP1 through Direct H4K20me Binding and H2AK15 Acetylation. Mol Cell. 2016 05 05; 62(3):409-421. PMID: 27153538.
      Citations: 73     Fields:    Translation:HumansCells
    46. Udayakumar D, Pandita RK, Horikoshi N, Liu Y, Liu Q, Wong KK, Hunt CR, Gray NS, Minna JD, Pandita TK, Westover KD. Torin2 Suppresses Ionizing Radiation-Induced DNA Damage Repair. Radiat Res. 2016 05; 185(5):527-38. PMID: 27135971.
      Citations: 5     Fields:    Translation:HumansCells
    47. Farooq Z, Banday S, Pandita TK, Altaf M. The many faces of histone H3K79 methylation. Mutat Res Rev Mutat Res. 2016 Apr-Jun; 768:46-52. PMID: 27234562.
      Citations: 31     Fields:    Translation:HumansAnimalsCells
    48. Mujoo K, Hunt CR, Horikoshi N, Pandita TK. A multifaceted role for MOF histone modifying factor in genome maintenance. Mech Ageing Dev. 2017 01; 161(Pt A):177-180. PMID: 27038808.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    49. Horikoshi N, Hunt CR, Pandita TK. More complex transcriptional regulation and stress response by MOF. Oncogene. 2016 05; 35(21):2681-3. PMID: 26434593.
      Citations: 3     Fields:    Translation:HumansCells
    50. Zhang J, Tripathi DN, Jing J, Alexander A, Kim J, Powell RT, Dere R, Tait-Mulder J, Lee JH, Paull TT, Pandita RK, Charaka VK, Pandita TK, Kastan MB, Walker CL. ATM functions at the peroxisome to induce pexophagy in response to ROS. Nat Cell Biol. 2015 Oct; 17(10):1259-1269. PMID: 26344566.
      Citations: 129     Fields:    Translation:HumansAnimalsCells
    51. Torres MJ, Pandita RK, Kulak O, Kumar R, Formstecher E, Horikoshi N, Mujoo K, Hunt CR, Zhao Y, Lum L, Zaman A, Yeaman C, White MA, Pandita TK. Role of the Exocyst Complex Component Sec6/8 in Genomic Stability. Mol Cell Biol. 2015 Nov; 35(21):3633-45. PMID: 26283729.
      Citations: 5     Fields:    Translation:HumansCells
    52. Chakraborty A, Wakamiya M, Venkova-Canova T, Pandita RK, Aguilera-Aguirre L, Sarker AH, Singh DK, Hosoki K, Wood TG, Sharma G, Cardenas V, Sarkar PS, Sur S, Pandita TK, Boldogh I, Hazra TK. Neil2-null Mice Accumulate Oxidized DNA Bases in the Transcriptionally Active Sequences of the Genome and Are Susceptible to Innate Inflammation. J Biol Chem. 2015 Oct 09; 290(41):24636-48. PMID: 26245904.
      Citations: 25     Fields:    Translation:HumansAnimalsCells
    53. Pandita TK. USP7 saves RIDDLE for the end. Cell Cycle. 2015; 14(13):1999. PMID: 26017280.
      Citations:    Translation:HumansCells
    54. Chun SG, Park H, Pandita RK, Horikoshi N, Pandita TK, Schwartz DL, Yordy JS. Targeted inhibition of histone deacetylases and hedgehog signaling suppress tumor growth and homologous recombination in aerodigestive cancers. Am J Cancer Res. 2015; 5(4):1337-52. PMID: 26101701.
      Citations: 5     
    55. Ge C, Che L, Ren J, Pandita RK, Lu J, Li K, Pandita TK, Du C. BRUCE regulates DNA double-strand break response by promoting USP8 deubiquitination of BRIT1. Proc Natl Acad Sci U S A. 2015 Mar 17; 112(11):E1210-9. PMID: 25733871.
      Citations: 18     Fields:    Translation:HumansAnimalsCells
    56. Chatterjee A, Saha S, Chakraborty A, Silva-Fernandes A, Mandal SM, Neves-Carvalho A, Liu Y, Pandita RK, Hegde ML, Hegde PM, Boldogh I, Ashizawa T, Koeppen AH, Pandita TK, Maciel P, Sarkar PS, Hazra TK. The role of the mammalian DNA end-processing enzyme polynucleotide kinase 3'-phosphatase in spinocerebellar ataxia type 3 pathogenesis. PLoS Genet. 2015 Jan; 11(1):e1004749. PMID: 25633985.
      Citations: 28     Fields:    Translation:HumansAnimalsCells
    57. Pandita RK, Chow TT, Udayakumar D, Bain AL, Cubeddu L, Hunt CR, Shi W, Horikoshi N, Zhao Y, Wright WE, Khanna KK, Shay JW, Pandita TK. Single-strand DNA-binding protein SSB1 facilitates TERT recruitment to telomeres and maintains telomere G-overhangs. Cancer Res. 2015 Mar 01; 75(5):858-69. PMID: 25589350.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    58. Udayakumar D, Horikoshi N, Mishra L, Hunt C, Pandita TK. Detecting ATM-dependent chromatin modification in DNA damage response. Methods Mol Biol. 2015; 1288:317-36. PMID: 25827888.
      Citations: 2     Fields:    Translation:Cells
    59. Chakraborty S, Li L, Puliyappadamba VT, Guo G, Hatanpaa KJ, Mickey B, Souza RF, Vo P, Herz J, Chen MR, Boothman DA, Pandita TK, Wang DH, Sen GC, Habib AA. Constitutive and ligand-induced EGFR signalling triggers distinct and mutually exclusive downstream signalling networks. Nat Commun. 2014 Dec 15; 5:5811. PMID: 25503978.
      Citations: 31     Fields:    Translation:HumansCells
    60. Yadav VK, Thakur RK, Eckloff B, Baral A, Singh A, Halder R, Kumar A, Alam MP, Kundu TK, Pandita R, Pandita TK, Wieben ED, Chowdhury S. Promoter-proximal transcription factor binding is transcriptionally active when coupled with nucleosome repositioning in immediate vicinity. Nucleic Acids Res. 2014 Sep; 42(15):9602-11. PMID: 25081206.
      Citations: 6     Fields:    Translation:HumansCells
    61. Gupta A, Hunt CR, Hegde ML, Chakraborty S, Chakraborty S, Udayakumar D, Horikoshi N, Singh M, Ramnarain DB, Hittelman WN, Namjoshi S, Asaithamby A, Hazra TK, Ludwig T, Pandita RK, Tyler JK, Pandita TK. MOF phosphorylation by ATM regulates 53BP1-mediated double-strand break repair pathway choice. Cell Rep. 2014 Jul 10; 8(1):177-89. PMID: 24953651.
      Citations: 48     Fields:    Translation:HumansAnimalsCells
    62. Sun CK, Zhang F, Xiang T, Chen Q, Pandita TK, Huang Y, Hu MC, Yang Q. Phosphorylation of ribosomal protein S6 confers PARP inhibitor resistance in BRCA1-deficient cancers. Oncotarget. 2014 May 30; 5(10):3375-85. PMID: 24831086.
      Citations: 18     Fields:    Translation:HumansAnimalsCells
    63. Pandita TK. Unraveling the novel function of the DNA repair enzyme 8-oxoguanine-DNA glycosylase in activating key signaling pathways. Free Radic Biol Med. 2014 Aug; 73:439-40. PMID: 24878260.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    64. Bolderson E, Petermann E, Croft L, Suraweera A, Pandita RK, Pandita TK, Helleday T, Khanna KK, Richard DJ. Human single-stranded DNA binding protein 1 (hSSB1/NABP2) is required for the stability and repair of stalled replication forks. Nucleic Acids Res. 2014 Jun; 42(10):6326-36. PMID: 24753408.
      Citations: 26     Fields:    Translation:HumansCells
    65. Wang H, Adhikari S, Butler BE, Pandita TK, Mitra S, Hegde ML. A Perspective on Chromosomal Double Strand Break Markers in Mammalian Cells. Jacobs J Radiat Oncol. 2014; 1(1). PMID: 25614903.
      Citations: 16     
    66. Gupta A, Hunt CR, Chakraborty S, Pandita RK, Yordy J, Ramnarain DB, Horikoshi N, Pandita TK. Role of 53BP1 in the regulation of DNA double-strand break repair pathway choice. Radiat Res. 2014 Jan; 181(1):1-8. PMID: 24320053.
      Citations: 35     Fields:    Translation:HumansAnimalsCells
    67. Pushpavalli SN, Sarkar A, Bag I, Hunt CR, Ramaiah MJ, Pandita TK, Bhadra U, Pal-Bhadra M. Argonaute-1 functions as a mitotic regulator by controlling Cyclin B during Drosophila early embryogenesis. FASEB J. 2014 Feb; 28(2):655-66. PMID: 24165481.
      Citations: 6     Fields:    Translation:AnimalsCells
    68. Zhang Y, Zhang X, Shan P, Hunt CR, Pandita TK, Lee PJ. A protective Hsp70-TLR4 pathway in lethal oxidant lung injury. J Immunol. 2013 Aug 01; 191(3):1393-403. PMID: 23817427.
      Citations: 18     Fields:    Translation:AnimalsCells
    69. Laine A, Iyengar P, Pandita TK. The role of inflammatory pathways in cancer-associated cachexia and radiation resistance. Mol Cancer Res. 2013 Sep; 11(9):967-72. PMID: 23788634.
      Citations: 15     Fields:    Translation:Humans
    70. Pandita TK. Histone H4 lysine 16 acetylated isoform synthesis opens new route to biophysical studies. Proteomics. 2013 May; 13(10-11):1546-7. PMID: 23595999.
      Citations: 4     Fields:    Translation:HumansCells
    71. Horikoshi N, Kumar P, Sharma GG, Chen M, Hunt CR, Westover K, Chowdhury S, Pandita TK. Genome-wide distribution of histone H4 Lysine 16 acetylation sites and their relationship to gene expression. Genome Integr. 2013 Apr 12; 4(1):3. PMID: 23587301.
      Citations: 24     
    72. Yang Y, Fiskus W, Yong B, Atadja P, Takahashi Y, Pandita TK, Wang HG, Bhalla KN. Acetylated hsp70 and KAP1-mediated Vps34 SUMOylation is required for autophagosome creation in autophagy. Proc Natl Acad Sci U S A. 2013 Apr 23; 110(17):6841-6. PMID: 23569248.
      Citations: 73     Fields:    Translation:HumansAnimalsCells
    73. Gupta A, Hunt CR, Pandita RK, Pae J, Komal K, Singh M, Shay JW, Kumar R, Ariizumi K, Horikoshi N, Hittelman WN, Guha C, Ludwig T, Pandita TK. T-cell-specific deletion of Mof blocks their differentiation and results in genomic instability in mice. Mutagenesis. 2013 May; 28(3):263-70. PMID: 23386701.
      Citations: 22     Fields:    Translation:AnimalsCells
    74. Hunt CR, Ramnarain D, Horikoshi N, Iyengar P, Pandita RK, Shay JW, Pandita TK. Histone modifications and DNA double-strand break repair after exposure to ionizing radiations. Radiat Res. 2013 Apr; 179(4):383-92. PMID: 23373901.
      Citations: 52     Fields:    Translation:HumansCells
    75. Kumar R, Horikoshi N, Singh M, Gupta A, Misra HS, Albuquerque K, Hunt CR, Pandita TK. Chromatin modifications and the DNA damage response to ionizing radiation. Front Oncol. 2012; 2:214. PMID: 23346550.
      Citations: 25     
    76. Singh M, Hunt CR, Pandita RK, Kumar R, Yang CR, Horikoshi N, Bachoo R, Serag S, Story MD, Shay JW, Powell SN, Gupta A, Jeffery J, Pandita S, Chen BP, Deckbar D, Löbrich M, Yang Q, Khanna KK, Worman HJ, Pandita TK. Lamin A/C depletion enhances DNA damage-induced stalled replication fork arrest. Mol Cell Biol. 2013 Mar; 33(6):1210-22. PMID: 23319047.
      Citations: 40     Fields:    Translation:HumansAnimalsCells
    77. Mirza S, Katafiasz BJ, Kumar R, Wang J, Mohibi S, Jain S, Gurumurthy CB, Pandita TK, Dave BJ, Band H, Band V. Alteration/deficiency in activation-3 (Ada3) plays a critical role in maintaining genomic stability. Cell Cycle. 2012 Nov 15; 11(22):4266-74. PMID: 23095635.
      Citations: 12     Translation:AnimalsCells
    78. Sparks JL, Kumar R, Singh M, Wold MS, Pandita TK, Burgers PM. Human exonuclease 5 is a novel sliding exonuclease required for genome stability. J Biol Chem. 2012 Dec 14; 287(51):42773-83. PMID: 23095756.
      Citations: 6     Fields:    Translation:HumansCells
    79. Kim SB, Pandita RK, Eskiocak U, Ly P, Kaisani A, Kumar R, Cornelius C, Wright WE, Pandita TK, Shay JW. Targeting of Nrf2 induces DNA damage signaling and protects colonic epithelial cells from ionizing radiation. Proc Natl Acad Sci U S A. 2012 Oct 23; 109(43):E2949-55. PMID: 23045680.
      Citations: 58     Fields:    Translation:AnimalsCells
    80. Pandita TK. 14th International Workshop on Ataxia-Telangiectasia ATW2012. DNA Repair (Amst). 2012 Oct 01; 11(10):853-6. PMID: 22921572.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    81. Chaurasia P, Sen R, Pandita TK, Bhaumik SR. Preferential repair of DNA double-strand break at the active gene in vivo. J Biol Chem. 2012 Oct 19; 287(43):36414-22. PMID: 22910905.
      Citations: 9     Fields:    Translation:AnimalsCells
    82. Blickwedehl J, Olejniczak S, Cummings R, Sarvaiya N, Mantilla A, Chanan-Khan A, Pandita TK, Schmidt M, Thompson CB, Bangia N. The proteasome activator PA200 regulates tumor cell responsiveness to glutamine and resistance to ionizing radiation. Mol Cancer Res. 2012 Jul; 10(7):937-44. PMID: 22550082.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    83. Hunt CR, Gupta A, Horikoshi N, Pandita TK. Does PTEN loss impair DNA double-strand break repair by homologous recombination? Clin Cancer Res. 2012 Feb 15; 18(4):920-2. PMID: 22179663.
      Citations: 12     Fields:    Translation:HumansAnimals
    84. Bhadra MP, Horikoshi N, Pushpavallipvalli SN, Sarkar A, Bag I, Krishnan A, Lucchesi JC, Kumar R, Yang Q, Pandita RK, Singh M, Bhadra U, Eissenberg JC, Pandita TK. The role of MOF in the ionizing radiation response is conserved in Drosophila melanogaster. Chromosoma. 2012 Feb; 121(1):79-90. PMID: 22072291.
      Citations: 15     Fields:    Translation:AnimalsCells
    85. Fukuyo Y, Takahashi A, Hara E, Horikoshi N, Pandita TK, Nakajima T. E2FBP1 antagonizes the p16(INK4A)-Rb tumor suppressor machinery for growth suppression and cellular senescence by regulating promyelocytic leukemia protein stability. Int J Oral Sci. 2011 Oct; 3(4):200-8. PMID: 22010578.
      Citations: 6     Fields:    Translation:HumansCells
    86. Jiang Z, Kamath R, Jin S, Balasubramani M, Pandita TK, Rajasekaran B. Tip60-mediated acetylation activates transcription independent apoptotic activity of Abl. Mol Cancer. 2011 Jul 22; 10:88. PMID: 21781306.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    87. Kumar R, Hunt CR, Gupta A, Nannepaga S, Pandita RK, Shay JW, Bachoo R, Ludwig T, Burns DK, Pandita TK. Purkinje cell-specific males absent on the first (mMof) gene deletion results in an ataxia-telangiectasia-like neurological phenotype and backward walking in mice. Proc Natl Acad Sci U S A. 2011 Mar 01; 108(9):3636-41. PMID: 21321203.
      Citations: 29     Fields:    Translation:AnimalsCells
    88. Feng Z, Scott SP, Bussen W, Sharma GG, Guo G, Pandita TK, Powell SN. Rad52 inactivation is synthetically lethal with BRCA2 deficiency. Proc Natl Acad Sci U S A. 2011 Jan 11; 108(2):686-91. PMID: 21148102.
      Citations: 150     Fields:    Translation:HumansCells
    89. Liu H, Takeda S, Kumar R, Westergard TD, Brown EJ, Pandita TK, Cheng EH, Hsieh JJ. Phosphorylation of MLL by ATR is required for execution of mammalian S-phase checkpoint. Nature. 2010 Sep 16; 467(7313):343-6. PMID: 20818375.
      Citations: 65     Fields:    Translation:HumansAnimalsCells
    90. Lo PK, Lee JS, Liang X, Han L, Mori T, Fackler MJ, Sadik H, Argani P, Pandita TK, Sukumar S. Epigenetic inactivation of the potential tumor suppressor gene FOXF1 in breast cancer. Cancer Res. 2010 Jul 15; 70(14):6047-58. PMID: 20587515.
      Citations: 39     Fields:    Translation:HumansCells
    91. Sharma GG, So S, Gupta A, Kumar R, Cayrou C, Avvakumov N, Bhadra U, Pandita RK, Porteus MH, Chen DJ, Cote J, Pandita TK. MOF and histone H4 acetylation at lysine 16 are critical for DNA damage response and double-strand break repair. Mol Cell Biol. 2010 Jul; 30(14):3582-95. PMID: 20479123.
      Citations: 139     Fields:    Translation:HumansCells
    92. Bolderson E, Tomimatsu N, Richard DJ, Boucher D, Kumar R, Pandita TK, Burma S, Khanna KK. Phosphorylation of Exo1 modulates homologous recombination repair of DNA double-strand breaks. Nucleic Acids Res. 2010 Apr; 38(6):1821-31. PMID: 20019063.
      Citations: 88     Fields:    Translation:HumansCells
    93. Zietara N, Lyszkiewicz M, Gekara N, Puchalka J, Dos Santos VA, Hunt CR, Pandita TK, Lienenklaus S, Weiss S. Absence of IFN-beta impairs antigen presentation capacity of splenic dendritic cells via down-regulation of heat shock protein 70. J Immunol. 2009 Jul 15; 183(2):1099-109. PMID: 19581626.
      Citations: 18     Fields:    Translation:AnimalsCells
    94. Li Y, Bolderson E, Kumar R, Muniandy PA, Xue Y, Richard DJ, Seidman M, Pandita TK, Khanna KK, Wang W. HSSB1 and hSSB2 form similar multiprotein complexes that participate in DNA damage response. J Biol Chem. 2009 Aug 28; 284(35):23525-31. PMID: 19605351.
      Citations: 54     Fields:    Translation:HumansCells
    95. Gupta A, Yang Q, Pandita RK, Hunt CR, Xiang T, Misri S, Zeng S, Pagan J, Jeffery J, Puc J, Kumar R, Feng Z, Powell SN, Bhat A, Yaguchi T, Wadhwa R, Kaul SC, Parsons R, Khanna KK, Pandita TK. Cell cycle checkpoint defects contribute to genomic instability in PTEN deficient cells independent of DNA DSB repair. Cell Cycle. 2009 Jul 15; 8(14):2198-210. PMID: 19502790.
      Citations: 60     Translation:HumansCells
    96. Zeng S, Xiang T, Pandita TK, Gonzalez-Suarez I, Gonzalo S, Harris CC, Yang Q. Telomere recombination requires the MUS81 endonuclease. Nat Cell Biol. 2009 May; 11(5):616-23. PMID: 19363487.
      Citations: 53     Fields:    Translation:HumansAnimalsCells
    97. Zou Y, Misri S, Shay JW, Pandita TK, Wright WE. Altered states of telomere deprotection and the two-stage mechanism of replicative aging. Mol Cell Biol. 2009 May; 29(9):2390-7. PMID: 19223460.
      Citations: 8     Fields:    Translation:HumansCells
    98. Helmink BA, Bredemeyer AL, Lee BS, Huang CY, Sharma GG, Walker LM, Bednarski JJ, Lee WL, Pandita TK, Bassing CH, Sleckman BP. MRN complex function in the repair of chromosomal Rag-mediated DNA double-strand breaks. J Exp Med. 2009 Mar 16; 206(3):669-79. PMID: 19221393.
      Citations: 53     Fields:    Translation:HumansAnimalsCells
    99. Misri S, Pandita S, Kumar R, Pandita TK. Telomeres, histone code, and DNA damage response. Cytogenet Genome Res. 2008; 122(3-4):297-307. PMID: 19188699.
      Citations: 26     Fields:    Translation:HumansCells
    100. Pandita TK, Richardson C. Chromatin remodeling finds its place in the DNA double-strand break response. Nucleic Acids Res. 2009 Apr; 37(5):1363-77. PMID: 19139074.
      Citations: 67     Fields:    Translation:HumansCells
    101. Misri S, Pandita S, Pandita TK. Detecting ATM-dependent chromatin modification in DNA damage and heat shock response. Methods Mol Biol. 2009; 523:395-410. PMID: 19381924.
      Citations: 4     Fields:    Translation:HumansCells
    102. Pandita TK, Pandita S, Bhaumik SR. Molecular parameters of hyperthermia for radiosensitization. Crit Rev Eukaryot Gene Expr. 2009; 19(3):235-51. PMID: 19883367.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    103. Xiang T, Ohashi A, Huang Y, Pandita TK, Ludwig T, Powell SN, Yang Q. Negative Regulation of AKT Activation by BRCA1. Cancer Res. 2008 Dec 15; 68(24):10040-4. PMID: 19074868.
      Citations: 59     Fields:    Translation:HumansAnimalsCells
    104. Aucott R, Bullwinkel J, Yu Y, Shi W, Billur M, Brown JP, Menzel U, Kioussis D, Wang G, Reisert I, Weimer J, Pandita RK, Sharma GG, Pandita TK, Fundele R, Singh PB. HP1-beta is required for development of the cerebral neocortex and neuromuscular junctions. J Cell Biol. 2008 Nov 17; 183(4):597-606. PMID: 19015315.
      Citations: 55     Fields:    Translation:HumansAnimalsCells
    105. Blickwedehl J, Agarwal M, Seong C, Pandita RK, Melendy T, Sung P, Pandita TK, Bangia N. Role for proteasome activator PA200 and postglutamyl proteasome activity in genomic stability. Proc Natl Acad Sci U S A. 2008 Oct 21; 105(42):16165-70. PMID: 18845680.
      Citations: 45     Fields:    Translation:HumansAnimalsCells
    106. Agarwal M, Pandita S, Hunt CR, Gupta A, Yue X, Khan S, Pandita RK, Pratt D, Shay JW, Taylor JS, Pandita TK. Inhibition of telomerase activity enhances hyperthermia-mediated radiosensitization. Cancer Res. 2008 May 01; 68(9):3370-8. PMID: 18451164.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    107. Richard DJ, Bolderson E, Cubeddu L, Wadsworth RI, Savage K, Sharma GG, Nicolette ML, Tsvetanov S, McIlwraith MJ, Pandita RK, Takeda S, Hay RT, Gautier J, West SC, Paull TT, Pandita TK, White MF, Khanna KK. Single-stranded DNA-binding protein hSSB1 is critical for genomic stability. Nature. 2008 May 29; 453(7195):677-81. PMID: 18449195.
      Citations: 103     Fields:    Translation:HumansCells
    108. Gupta A, Guerin-Peyrou TG, Sharma GG, Park C, Agarwal M, Ganju RK, Pandita S, Choi K, Sukumar S, Pandita RK, Ludwig T, Pandita TK. The mammalian ortholog of Drosophila MOF that acetylates histone H4 lysine 16 is essential for embryogenesis and oncogenesis. Mol Cell Biol. 2008 Jan; 28(1):397-409. PMID: 17967868.
      Citations: 106     Fields:    Translation:AnimalsCells
    109. Huang CY, Sharma GG, Walker LM, Bassing CH, Pandita TK, Sleckman BP. Defects in coding joint formation in vivo in developing ATM-deficient B and T lymphocytes. J Exp Med. 2007 Jun 11; 204(6):1371-81. PMID: 17502661.
      Citations: 29     Fields:    Translation:AnimalsCells
    110. Hunt CR, Pandita RK, Laszlo A, Higashikubo R, Agarwal M, Kitamura T, Gupta A, Rief N, Horikoshi N, Baskaran R, Lee JH, Löbrich M, Paull TT, Roti Roti JL, Pandita TK. Hyperthermia activates a subset of ataxia-telangiectasia mutated effectors independent of DNA strand breaks and heat shock protein 70 status. Cancer Res. 2007 Apr 01; 67(7):3010-7. PMID: 17409407.
      Citations: 60     Fields:    Translation:HumansAnimalsCells
    111. Rubin E, Wu X, Zhu T, Cheung JC, Chen H, Lorincz A, Pandita RK, Sharma GG, Ha HC, Gasson J, Hanakahi LA, Pandita TK, Sukumar S. A role for the HOXB7 homeodomain protein in DNA repair. Cancer Res. 2007 Feb 15; 67(4):1527-35. PMID: 17308091.
      Citations: 33     Fields:    Translation:HumansCells
    112. Pandita TK, Hunt CR, Sharma GG, Yang Q. Regulation of telomere movement by telomere chromatin structure. Cell Mol Life Sci. 2007 Jan; 64(2):131-8. PMID: 17219023.
      Citations: 11     Fields:    Translation:Cells
    113. Scott SP, Pandita TK. The cellular control of DNA double-strand breaks. J Cell Biochem. 2006 Dec 15; 99(6):1463-75. PMID: 16927314.
      Citations: 34     Fields:    Translation:HumansAnimalsCells
    114. Liebe B, Petukhova G, Barchi M, Bellani M, Braselmann H, Nakano T, Pandita TK, Jasin M, Fornace A, Meistrich ML, Baarends WM, Schimenti J, de Lange T, Keeney S, Camerini-Otero RD, Scherthan H. Mutations that affect meiosis in male mice influence the dynamics of the mid-preleptotene and bouquet stages. Exp Cell Res. 2006 Nov 15; 312(19):3768-81. PMID: 17010969.
      Citations: 27     Fields:    Translation:AnimalsCells
    115. Pandita TK. Role of mammalian Rad9 in genomic stability and ionizing radiation response. Cell Cycle. 2006 Jun; 5(12):1289-91. PMID: 16760671.
      Citations: 12     Translation:HumansAnimalsCells
    116. Bredemeyer AL, Sharma GG, Huang CY, Helmink BA, Walker LM, Khor KC, Nuskey B, Sullivan KE, Pandita TK, Bassing CH, Sleckman BP. ATM stabilizes DNA double-strand-break complexes during V(D)J recombination. Nature. 2006 Jul 27; 442(7101):466-70. PMID: 16799570.
      Citations: 191     Fields:    Translation:AnimalsCells
    117. Pandita RK, Sharma GG, Laszlo A, Hopkins KM, Davey S, Chakhparonian M, Gupta A, Wellinger RJ, Zhang J, Powell SN, Roti Roti JL, Lieberman HB, Pandita TK. Mammalian Rad9 plays a role in telomere stability, S- and G2-phase-specific cell survival, and homologous recombinational repair. Mol Cell Biol. 2006 Mar; 26(5):1850-64. PMID: 16479004.
      Citations: 80     Fields:    Translation:HumansAnimalsCells
    118. Seo J, Chung YS, Sharma GG, Moon E, Burack WR, Pandita TK, Choi K. Cdt1 transgenic mice develop lymphoblastic lymphoma in the absence of p53. Oncogene. 2005 Dec 08; 24(55):8176-86. PMID: 16261166.
      Citations: 38     Fields:    Translation:HumansAnimalsCells
    119. Pandita TK. Role of HSPs and telomerase in radiotherapy. Int J Hyperthermia. 2005 Dec; 21(8):689-94. PMID: 16338850.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    120. Ziv S, Brenner O, Amariglio N, Smorodinsky NI, Galron R, Carrion DV, Zhang W, Sharma GG, Pandita RK, Agarwal M, Elkon R, Katzin N, Bar-Am I, Pandita TK, Kucherlapati R, Rechavi G, Shiloh Y, Barzilai A. Impaired genomic stability and increased oxidative stress exacerbate different features of Ataxia-telangiectasia. Hum Mol Genet. 2005 Oct 01; 14(19):2929-43. PMID: 16150740.
      Citations: 7     Fields:    Translation:AnimalsCells
    121. Gupta A, Sharma GG, Young CS, Agarwal M, Smith ER, Paull TT, Lucchesi JC, Khanna KK, Ludwig T, Pandita TK. Involvement of human MOF in ATM function. Mol Cell Biol. 2005 Jun; 25(12):5292-305. PMID: 15923642.
      Citations: 101     Fields:    Translation:HumansAnimalsCells
    122. Locke J, Zeug A, Thompson D, Allan J, Mazzarella K, Novak P, Hanson D, Singh AK, Moros EG, Pandita TK. Localized versus regional hyperthermia: comparison of xenotransplants treated with a small animal ultrasound system and waterbath limb immersion. Int J Hyperthermia. 2005 May; 21(3):271-81. PMID: 16019853.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    123. Sarsour EH, Agarwal M, Pandita TK, Oberley LW, Goswami PC. Manganese superoxide dismutase protects the proliferative capacity of confluent normal human fibroblasts. J Biol Chem. 2005 May 06; 280(18):18033-41. PMID: 15743756.
      Citations: 30     Fields:    Translation:HumansCells
    124. Puc J, Keniry M, Li HS, Pandita TK, Choudhury AD, Memeo L, Mansukhani M, Murty VV, Gaciong Z, Meek SE, Piwnica-Worms H, Hibshoosh H, Parsons R. Lack of PTEN sequesters CHK1 and initiates genetic instability. Cancer Cell. 2005 Feb; 7(2):193-204. PMID: 15710331.
      Citations: 130     Fields:    Translation:HumansAnimalsCells
    125. Shahrabani-Gargir L, Pandita TK, Werner H. Ataxia-telangiectasia mutated gene controls insulin-like growth factor I receptor gene expression in a deoxyribonucleic acid damage response pathway via mechanisms involving zinc-finger transcription factors Sp1 and WT1. Endocrinology. 2004 Dec; 145(12):5679-87. PMID: 15345673.
      Citations: 17     Fields:    Translation:HumansCells
    126. Richardson C, Horikoshi N, Pandita TK. The role of the DNA double-strand break response network in meiosis. DNA Repair (Amst). 2004 Aug-Sep; 3(8-9):1149-64. PMID: 15279804.
      Citations: 29     Fields:    Translation:HumansAnimalsCells
    127. Pandita TK, Higashikubo R, Hunt CR. HSP70 and genomic stability. Cell Cycle. 2004 May; 3(5):591-2. PMID: 15044849.
      Citations: 5     Translation:AnimalsCells
    128. Pandita TK. Enrichment of cells in different phases of the cell cycle by centrifugal elutriation. Methods Mol Biol. 2004; 241:17-21. PMID: 14970643.
      Citations:    Fields:    Translation:HumansAnimals
    129. Pandita TK. Detecting the influence of cell cycle regulatory proteins on human telomeres. Methods Mol Biol. 2004; 241:329-39. PMID: 14970665.
      Citations:    Fields:    Translation:HumansCells
    130. Hunt CR, Dix DJ, Sharma GG, Pandita RK, Gupta A, Funk M, Pandita TK. Genomic instability and enhanced radiosensitivity in Hsp70.1- and Hsp70.3-deficient mice. Mol Cell Biol. 2004 Jan; 24(2):899-911. PMID: 14701760.
      Citations: 94     Fields:    Translation:AnimalsCells
    131. Sharma GG, Hwang KK, Pandita RK, Gupta A, Dhar S, Parenteau J, Agarwal M, Worman HJ, Wellinger RJ, Pandita TK. Human heterochromatin protein 1 isoforms HP1(Hsalpha) and HP1(Hsbeta) interfere with hTERT-telomere interactions and correlate with changes in cell growth and response to ionizing radiation. Mol Cell Biol. 2003 Nov; 23(22):8363-76. PMID: 14585993.
      Citations: 42     Fields:    Translation:HumansAnimalsCells
    132. Sharma GG, Hall EJ, Dhar S, Gupta A, Rao PH, Pandita TK. Telomere stability correlates with longevity of human beings exposed to ionizing radiations. Oncol Rep. 2003 Nov-Dec; 10(6):1733-6. PMID: 14534687.
      Citations: 7     Fields:    Translation:HumansCellsPHPublic Health
    133. Pandita TK. A multifaceted role for ATM in genome maintenance. Expert Rev Mol Med. 2003 Jun 20; 5(16):1-21. PMID: 14987398.
      Citations: 26     Fields:    Translation:HumansCells
    134. Sarkar D, Leszczyniecka M, Kang DC, Lebedeva IV, Valerie K, Dhar S, Pandita TK, Fisher PB. Down-regulation of Myc as a potential target for growth arrest induced by human polynucleotide phosphorylase (hPNPaseold-35) in human melanoma cells. J Biol Chem. 2003 Jul 04; 278(27):24542-51. PMID: 12721301.
      Citations: 25     Fields:    Translation:HumansCells
    135. Pandita TK, Roti Roti JL. Role of telomerase in radiocurability (review). Oncol Rep. 2003 Mar-Apr; 10(2):263-70. PMID: 12579256.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    136. Sharma GG, Gupta A, Wang H, Scherthan H, Dhar S, Gandhi V, Iliakis G, Shay JW, Young CS, Pandita TK. hTERT associates with human telomeres and enhances genomic stability and DNA repair. Oncogene. 2003 Jan 09; 22(1):131-46. PMID: 12527915.
      Citations: 78     Fields:    Translation:HumansCells
    137. Vafa O, Wade M, Kern S, Beeche M, Pandita TK, Hampton GM, Wahl GM. c-Myc can induce DNA damage, increase reactive oxygen species, and mitigate p53 function: a mechanism for oncogene-induced genetic instability. Mol Cell. 2002 May; 9(5):1031-44. PMID: 12049739.
      Citations: 321     Fields:    Translation:HumansCells
    138. Pandita TK. ATM function and telomere stability. Oncogene. 2002 Jan 21; 21(4):611-8. PMID: 11850786.
      Citations: 62     Fields:    Translation:HumansCells
    139. Pandita TK. The role of ATM in telomere structure and function. Radiat Res. 2001 Nov; 156(5 Pt 2):642-7. PMID: 11604086.
      Citations: 16     Fields:    Translation:HumansCells
    140. Vaziri H, Dessain SK, Ng Eaton E, Imai SI, Frye RA, Pandita TK, Guarente L, Weinberg RA. hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase. Cell. 2001 Oct 19; 107(2):149-59. PMID: 11672523.
      Citations: 934     Fields:    Translation:HumansAnimalsCells
    141. Gage BM, Alroy D, Shin CY, Ponomareva ON, Dhar S, Sharma GG, Pandita TK, Thayer MJ, Turker MS. Spontaneously immortalized cell lines obtained from adult Atm null mice retain sensitivity to ionizing radiation and exhibit a mutational pattern suggestive of oxidative stress. Oncogene. 2001 Jul 19; 20(32):4291-7. PMID: 11466609.
      Citations: 3     Fields:    Translation:AnimalsCells
    142. Wood LD, Halvorsen TL, Dhar S, Baur JA, Pandita RK, Wright WE, Hande MP, Calaf G, Hei TK, Levine F, Shay JW, Wang JJ, Pandita TK. Characterization of ataxia telangiectasia fibroblasts with extended life-span through telomerase expression. Oncogene. 2001 Jan 18; 20(3):278-88. PMID: 11313956.
      Citations: 23     Fields:    Translation:HumansAnimalsCells
    143. Gatei M, Shkedy D, Khanna KK, Uziel T, Shiloh Y, Pandita TK, Lavin MF, Rotman G. Ataxia-telangiectasia: chronic activation of damage-responsive functions is reduced by alpha-lipoic acid. Oncogene. 2001 Jan 18; 20(3):289-94. PMID: 11313957.
      Citations: 10     Fields:    Translation:HumansCells
    144. Dhar S, Squire JA, Hande MP, Wellinger RJ, Pandita TK. Inactivation of 14-3-3sigma influences telomere behavior and ionizing radiation-induced chromosomal instability. Mol Cell Biol. 2000 Oct; 20(20):7764-72. PMID: 11003671.
      Citations: 18     Fields:    Translation:HumansCells
    145. Scherthan H, Jerratsch M, Dhar S, Wang YA, Goff SP, Pandita TK. Meiotic telomere distribution and Sertoli cell nuclear architecture are altered in Atm- and Atm-p53-deficient mice. Mol Cell Biol. 2000 Oct; 20(20):7773-83. PMID: 11003672.
      Citations: 26     Fields:    Translation:AnimalsCells
    146. Fan Z, Chakravarty P, Alfieri A, Pandita TK, Vikram B, Guha C. Adenovirus-mediated antisense ATM gene transfer sensitizes prostate cancer cells to radiation. Cancer Gene Ther. 2000 Oct; 7(10):1307-14. PMID: 11059687.
      Citations: 10     Fields:    Translation:HumansCells
    147. Shangary S, Brown KD, Adamson AW, Edmonson S, Ng B, Pandita TK, Yalowich J, Taccioli GE, Baskaran R. Regulation of DNA-dependent protein kinase activity by ionizing radiation-activated abl kinase is an ATM-dependent process. J Biol Chem. 2000 Sep 29; 275(39):30163-8. PMID: 10906134.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    148. Pandita TK, Dhar S. Influence of ATM function on interactions between telomeres and nuclear matrix. Radiat Res. 2000 Aug; 154(2):133-9. PMID: 10931683.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    149. Ferguson AT, Evron E, Umbricht CB, Pandita TK, Chan TA, Hermeking H, Marks JR, Lambers AR, Futreal PA, Stampfer MR, Sukumar S. High frequency of hypermethylation at the 14-3-3 sigma locus leads to gene silencing in breast cancer. Proc Natl Acad Sci U S A. 2000 May 23; 97(11):6049-54. PMID: 10811911.
      Citations: 132     Fields:    Translation:HumansCells
    150. Kharbanda S, Kumar V, Dhar S, Pandey P, Chen C, Majumder P, Yuan ZM, Whang Y, Strauss W, Pandita TK, Weaver D, Kufe D. Regulation of the hTERT telomerase catalytic subunit by the c-Abl tyrosine kinase. Curr Biol. 2000 May 18; 10(10):568-75. PMID: 10837221.
      Citations: 39     Fields:    Translation:HumansCells
    151. Guha C, Guha U, Tribius S, Alfieri A, Casper D, Chakravarty P, Mellado W, Pandita TK, Vikram B. Antisense ATM gene therapy: a strategy to increase the radiosensitivity of human tumors. Gene Ther. 2000 May; 7(10):852-8. PMID: 10845723.
      Citations: 5     Fields:    Translation:HumansCells
    152. Pandita TK, Lieberman HB, Lim DS, Dhar S, Zheng W, Taya Y, Kastan MB. Ionizing radiation activates the ATM kinase throughout the cell cycle. Oncogene. 2000 Mar 09; 19(11):1386-91. PMID: 10723129.
      Citations: 55     Fields:    Translation:HumansCells
    153. Fu W, Killen M, Culmsee C, Dhar S, Pandita TK, Mattson MP. The catalytic subunit of telomerase is expressed in developing brain neurons and serves a cell survival-promoting function. J Mol Neurosci. 2000 Feb-Apr; 14(1-2):3-15. PMID: 10854032.
      Citations: 36     Fields:    Translation:AnimalsCells
    154. Smilenov LB, Dhar S, Pandita TK. Altered telomere nuclear matrix interactions and nucleosomal periodicity in ataxia telangiectasia cells before and after ionizing radiation treatment. Mol Cell Biol. 1999 Oct; 19(10):6963-71. PMID: 10490633.
      Citations: 23     Fields:    Translation:HumansCells
    155. Rakovitch E, Mellado W, Hall EJ, Pandita TK, Sawant S, Geard CR. Paclitaxel sensitivity correlates with p53 status and DNA fragmentation, but not G2/M accumulation. Int J Radiat Oncol Biol Phys. 1999 Jul 15; 44(5):1119-24. PMID: 10421546.
      Citations: 7     Fields:    Translation:HumansCells
    156. Pandita TK, Westphal CH, Anger M, Sawant SG, Geard CR, Pandita RK, Scherthan H. Atm inactivation results in aberrant telomere clustering during meiotic prophase. Mol Cell Biol. 1999 Jul; 19(7):5096-105. PMID: 10373558.
      Citations: 30     Fields:    Translation:AnimalsCells
    157. Sawant SG, Gregoire V, Dhar S, Umbricht CB, Cvilic S, Sukumar S, Pandita TK. Telomerase activity as a measure for monitoring radiocurability of tumor cells. FASEB J. 1999 Jun; 13(9):1047-54. PMID: 10336887.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    158. Vaziri H, Squire JA, Pandita TK, Bradley G, Kuba RM, Zhang H, Gulyas S, Hill RP, Nolan GP, Benchimol S. Analysis of genomic integrity and p53-dependent G1 checkpoint in telomerase-induced extended-life-span human fibroblasts. Mol Cell Biol. 1999 Mar; 19(3):2373-9. PMID: 10022923.
      Citations: 19     Fields:    Translation:HumansCells
    159. Rakovitch E, Mellado W, Hall EJ, Sawant SG, Geard CR, Newman RA, Pandita TK. Penclomedine-induced DNA fragmentation and p53 accumulation correlate with reproductive cell death in colorectal carcinoma cells with altered p53 status. Oncol Rep. 1999 Jan-Feb; 6(1):161-5. PMID: 9864421.
      Citations:    Fields:    Translation:Cells
    160. Hall EJ, Schiff PB, Hanks GE, Brenner DJ, Russo J, Chen J, Sawant SG, Pandita TK. A preliminary report: frequency of A-T heterozygotes among prostate cancer patients with severe late responses to radiation therapy. Cancer J Sci Am. 1998 Nov-Dec; 4(6):385-9. PMID: 9853138.
      Citations: 17     Fields:    Translation:HumansPHPublic Health
    161. Smilenov LB, Mellado W, Rao PH, Sawant SG, Umbricht CB, Sukumar S, Pandita TK. Molecular cloning and chromosomal localization of Chinese hamster telomeric protein chTRF1. Its potential role in chromosomal instability. Oncogene. 1998 Oct 22; 17(16):2137-42. PMID: 9798685.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    162. Kharbanda S, Pandey P, Morris PL, Whang Y, Xu Y, Sawant S, Zhu LJ, Kumar N, Yuan ZM, Weichselbaum R, Sawyers CL, Pandita TK, Kufe D. Functional role for the c-Abl tyrosine kinase in meiosis I. Oncogene. 1998 Apr 09; 16(14):1773-7. PMID: 9583675.
      Citations: 8     Fields:    Translation:AnimalsCells
    163. Smilenov LB, Morgan SE, Mellado W, Sawant SG, Kastan MB, Pandita TK. Influence of ATM function on telomere metabolism. Oncogene. 1997 Nov 27; 15(22):2659-65. PMID: 9400992.
      Citations: 27     Fields:    Translation:HumansAnimalsCells
    164. Morgan SE, Lovly C, Pandita TK, Shiloh Y, Kastan MB. Fragments of ATM which have dominant-negative or complementing activity. Mol Cell Biol. 1997 Apr; 17(4):2020-9. PMID: 9121450.
      Citations: 44     Fields:    Translation:HumansCells
    165. Pandita TK, Benvenuto JA, Shay JW, Pandita RK, Rakovitch E, Geard CR, Antman KH, Newman RA. Effect of penclomedine (NSC-338720) on telomere fusions, chromatin blebbing, and cell viability with and without telomerase activity and abrogated p53 function. Biochem Pharmacol. 1997 Feb 07; 53(3):409-15. PMID: 9065745.
      Citations: 2     Fields:    Translation:HumansCells
    166. Bouffler SD, Morgan WF, Pandita TK, Slijepcevic P. The involvement of telomeric sequences in chromosomal aberrations. Mutat Res. 1996 Nov; 366(2):129-35. PMID: 9001579.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    167. Freyer GA, Palmer DA, Yu Y, Miller RC, Pandita TK. Neoplastic transformation of mouse C3H10T1/2 cells following exposure to neutrons does not involve mutation of ras gene as analyzed by SSCP and cycle sequencing. Mutat Res. 1996 Oct 25; 357(1-2):237-44. PMID: 8876700.
      Citations: 7     Fields:    Translation:AnimalsCells
    168. Pandita TK, Hall EJ, Hei TK, Piatyszek MA, Wright WE, Piao CQ, Pandita RK, Willey JC, Geard CR, Kastan MB, Shay JW. Chromosome end-to-end associations and telomerase activity during cancer progression in human cells after treatment with alpha-particles simulating radon progeny. Oncogene. 1996 Oct 03; 13(7):1423-30. PMID: 8875980.
      Citations: 16     Fields:    Translation:HumansCells
    169. Pandita TK, Geard CR. Chromosome aberrations in human fibroblasts induced by monoenergetic neutrons. I. Relative biological effectiveness. Radiat Res. 1996 Jun; 145(6):730-9. PMID: 8643833.
      Citations: 11     Fields:    Translation:HumansCells
    170. Benvenuto JA, Hittelman WN, Zwelling LA, Plunkett W, Pandita TK, Farquhar D, Newman RA. Biochemical pharmacology of penclomedine (NSC-338720). Biochem Pharmacol. 1995 Oct 12; 50(8):1157-64. PMID: 7488229.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    171. Pandita TK, Hittelman WN. Evidence of a chromatin basis for increased mutagen sensitivity associated with multiple primary malignancies of the head and neck. Int J Cancer. 1995 May 29; 61(5):738-43. PMID: 7539412.
      Citations: 8     Fields:    Translation:HumansCells
    172. Pandita TK, DeRubeis D. Spontaneous amplification of interstitial telomeric bands in Chinese hamster ovary cells. Cytogenet Cell Genet. 1995; 68(1-2):95-101. PMID: 7956371.
      Citations: 9     Fields:    Translation:AnimalsCells
    173. Pandita TK, Pathak S, Geard CR. Chromosome end associations, telomeres and telomerase activity in ataxia telangiectasia cells. Cytogenet Cell Genet. 1995; 71(1):86-93. PMID: 7606935.
      Citations: 46     Fields:    Translation:HumansCells
    174. Hittelman WN, Pandita TK. Possible role of chromatin alteration in the radiosensitivity of ataxia-telangiectasia. Int J Radiat Biol. 1994 Dec; 66(6 Suppl):S109-13. PMID: 7836837.
      Citations: 6     Fields:    Translation:HumansCells
    175. Pandita TK, Hittelman WN. Increased initial levels of chromosome damage and heterogeneous chromosome repair in ataxia telangiectasia heterozygote cells. Mutat Res. 1994 Oct 01; 310(1):1-13. PMID: 7523872.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    176. Dhingra K, Sneige N, Pandita TK, Johnston DA, Lee JS, Emami K, Hortobagyi GN, Hittelman WN. Quantitative analysis of chromosome in situ hybridization signal in paraffin-embedded tissue sections. Cytometry. 1994 Jun 01; 16(2):100-12. PMID: 7924678.
      Citations: 7     Fields:    Translation:HumansCells
    177. Pandita TK, Gregoire V, Dhingra K, Hittelman WN. Effect of chromosome size on aberration levels caused by gamma radiation as detected by fluorescence in situ hybridization. Cytogenet Cell Genet. 1994; 67(2):94-101. PMID: 8039428.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    178. Nishikawa K, Rosenblum MG, Newman RA, Pandita TK, Hittelman WN, Donato NJ. Resistance of human cervical carcinoma cells to tumor necrosis factor correlates with their increased sensitivity to cisplatin: evidence of a role for DNA repair and epidermal growth factor receptor. Cancer Res. 1992 Sep 01; 52(17):4758-65. PMID: 1380890.
      Citations: 5     Fields:    Translation:HumansCells
    179. Pandita TK, Hittelman WN. The contribution of DNA and chromosome repair deficiencies to the radiosensitivity of ataxia-telangiectasia. Radiat Res. 1992 Aug; 131(2):214-23. PMID: 1641475.
      Citations: 31     Fields:    Translation:HumansCells
    180. Pandita TK, Hittelman WN. Initial chromosome damage but not DNA damage is greater in ataxia telangiectasia cells. Radiat Res. 1992 Apr; 130(1):94-103. PMID: 1561323.
      Citations: 29     Fields:    Translation:HumansCells
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