"Tumor Microenvironment" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The milieu surrounding neoplasms consisting of cells, vessels, soluble factors, and molecules, that can influence and be influenced by, the neoplasm's growth.
| Descriptor ID |
D059016
|
| MeSH Number(s) |
G04.366.500
|
| Concept/Terms |
Tumor Microenvironment- Tumor Microenvironment
- Microenvironment, Tumor
- Microenvironments, Tumor
- Tumor Microenvironments
Cancer Microenvironment- Cancer Microenvironment
- Cancer Microenvironments
- Microenvironment, Cancer
- Microenvironments, Cancer
|
Below are MeSH descriptors whose meaning is more general than "Tumor Microenvironment".
Below are MeSH descriptors whose meaning is more specific than "Tumor Microenvironment".
This graph shows the total number of publications written about "Tumor Microenvironment" by people in this website by year, and whether "Tumor Microenvironment" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 0 | 2 | 2 |
| 2011 | 2 | 3 | 5 |
| 2012 | 4 | 2 | 6 |
| 2013 | 0 | 5 | 5 |
| 2014 | 4 | 4 | 8 |
| 2015 | 4 | 9 | 13 |
| 2016 | 7 | 8 | 15 |
| 2017 | 6 | 17 | 23 |
| 2018 | 7 | 15 | 22 |
| 2019 | 13 | 18 | 31 |
| 2020 | 17 | 25 | 42 |
| 2021 | 11 | 28 | 39 |
| 2022 | 5 | 45 | 50 |
| 2023 | 6 | 44 | 50 |
| 2024 | 15 | 22 | 37 |
| 2025 | 15 | 32 | 47 |
| 2026 | 1 | 6 | 7 |
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Below are the most recent publications written about "Tumor Microenvironment" by people in Profiles.
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Alprazolam Reduces Inflammatory Cytokine Production in Pancreatic Cancer-Associated Fibroblasts. Cancer Res Commun. 2026 May 01; 6(5):1048-1060.
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Single-cell TCR mapping reveals spatially coordinated T cell states in head and neck cancer. Sci Immunol. 2026 Apr 10; 11(118):eaec3133.
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Steroid receptor coactivator 3-deficient regulatory T cells eradicate multiple solid tumors in syngeneic mouse models. Oncoimmunology. 2026 Dec 31; 15(1):2640261.
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Tumor microenvironment transcriptional activity enables robust stratification of chemotherapy response in triple-negative breast cancer. Cell Rep Med. 2026 Feb 17; 7(2):102610.
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Multi-omics reveals that CTHRC1 secreted by cancer-associated fibroblasts promotes EMT by ITGA5/PI3K/AKT signaling pathway in HNSCC. Cell Signal. 2026 Jun; 142:112409.
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Spatial Profiling Reveals Distinct Molecular and Immune Evolution of Mouse Lung Adenocarcinoma Precancers with or Without Carcinogen Exposure. Adv Sci (Weinh). 2026 Mar; 13(17):e12597.
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Anti-CSF-1R therapy with combined immuno-chemotherapy coordinate an adaptive immune response to eliminate macrophage enriched triple negative breast cancers. Nat Commun. 2026 Jan 03; 17(1):1193.
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A Spatiotemporal Model of CXCL10 as a Master Regulator of Immune Evasion and Metastasis in Osteosarcoma. Int J Mol Sci. 2025 Dec 27; 27(1).
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Facts and Hopes of Chimeric Antigen Receptor-Redirected NK T Cells. Clin Cancer Res. 2025 Dec 15; 31(24):5137-5144.
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Personalized CRISPR knock-in cytokine gene therapy to remodel the tumor microenvironment and enhance CAR T cell therapy in solid tumors. Nat Commun. 2025 Dec 09; 16(1):10987.