Molecular Targeted Therapy

"Molecular Targeted Therapy" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Treatments with drugs which interact with or block synthesis of specific cellular components characteristic of the individual's disease in order to stop or interrupt the specific biochemical dysfunction involved in progression of the disease.

Descriptor ID	D058990
MeSH Number(s)	E02.319.574
Concept/Terms	Molecular Targeted Therapy Molecular Targeted Therapy Molecular Targeted Therapies Targeted Therapies, Molecular Targeted Therapy, Molecular Therapies, Molecular Targeted Therapy, Molecular Targeted Targeted Molecular Therapy Molecular Therapies, Targeted Molecular Therapy, Targeted Targeted Molecular Therapies Therapies, Targeted Molecular Therapy, Targeted Molecular

Below are MeSH descriptors whose meaning is more general than "Molecular Targeted Therapy".

Analytical, Diagnostic and Therapeutic Techniques and Equipment [E]
Therapeutics [E02]
Drug Therapy [E02.319]
Molecular Targeted Therapy [E02.319.574]

Below are MeSH descriptors whose meaning is more specific than "Molecular Targeted Therapy".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Molecular Targeted Therapy" by people in this website by year, and whether "Molecular Targeted Therapy" was a major or minor topic of these publications.

Bar chart showing 1018 publications over 13 distinct years, with a maximum of 125 publications in 2017

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2007	1	0	1
2009	0	1	1
2010	8	19	27
2011	31	60	91
2012	35	49	84
2013	37	56	93
2014	41	64	105
2015	49	70	119
2016	39	77	116
2017	35	90	125
2018	50	66	116
2019	33	72	105
2020	15	20	35

Below are the most recent publications written about "Molecular Targeted Therapy" by people in Profiles.

Reddy TP, Rosato RR, Li X, Moulder S, Piwnica-Worms H, Chang JC. A comprehensive overview of metaplastic breast cancer: clinical features and molecular aberrations. Breast Cancer Res. 2020 11 04; 22(1):121.

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Migut AE, Kaur H, Avritscher R. Neuroendocrine Tumors: Imaging of Treatment and Follow-up. Radiol Clin North Am. 2020 Nov; 58(6):1161-1171.

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Redman MW, Papadimitrakopoulou VA, Minichiello K, Hirsch FR, Mack PC, Schwartz LH, Vokes E, Ramalingam S, Leighl N, Bradley J, Miao J, Moon J, Highleyman L, Miwa C, LeBlanc ML, Malik S, Miller VA, Sigal EV, Adam S, Wholley D, Sigman C, Smolich B, Blanke CD, Kelly K, Gandara DR, Herbst RS. Biomarker-driven therapies for previously treated squamous non-small-cell lung cancer (Lung-MAP SWOG S1400): a biomarker-driven master protocol. Lancet Oncol. 2020 12; 21(12):1589-1601.

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Mughal TI, Pemmaraju N, Psaila B, Radich J, Bose P, Lion T, Kiladjian JJ, Rampal R, Jain T, Verstovsek S, Yacoub A, Cortes JE, Mesa R, Saglio G, van Etten RA. Illuminating novel biological aspects and potential new therapeutic approaches for chronic myeloproliferative malignancies. Hematol Oncol. 2020 Dec; 38(5):654-664.

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Marian AJ. Current state of vaccine development and targeted therapies for COVID-19: impact of basic science discoveries. Cardiovasc Pathol. 2021 Jan - Feb; 50:107278.

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Xie W, Medeiros LJ, Li S, Yin CC, Khoury JD, Xu J. PD-1/PD-L1 Pathway and Its Blockade in Patients with Classic Hodgkin Lymphoma and Non-Hodgkin Large-Cell Lymphomas. Curr Hematol Malig Rep. 2020 08; 15(4):372-381.

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Heuser M, Palmisiano N, Mantzaris I, Mims A, DiNardo C, Silverman LR, Wang ES, Fiedler W, Baldus C, Schwind S, Pardee T, Perl AE, Cai C, Kaulfuss S, Lagkadinou E, Rentzsch C, Wagner M, Wilkinson G, Wu B, Jeffers M, Genvresse I, Krämer A. Safety and efficacy of BAY1436032 in IDH1-mutant AML: phase I study results. Leukemia. 2020 11; 34(11):2903-2913.

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Hingorani P, Dinu V, Zhang X, Lei H, Shern JF, Park J, Steel J, Rauf F, Parham D, Gastier-Foster J, Hall D, Hawkins DS, Skapek SX, Labaer J, McEachron TA. Transcriptome analysis of desmoplastic small round cell tumors identifies actionable therapeutic targets: a report from the Children's Oncology Group. Sci Rep. 2020 07 23; 10(1):12318.

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Konopleva M, Martinelli G, Daver N, Papayannidis C, Wei A, Higgins B, Ott M, Mascarenhas J, Andreeff M. MDM2 inhibition: an important step forward in cancer therapy. Leukemia. 2020 11; 34(11):2858-2874.

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Pestana RC, Sen S, Hobbs BP, Hong DS. Histology-agnostic drug development - considering issues beyond the tissue. Nat Rev Clin Oncol. 2020 09; 17(9):555-568.

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