"Hemochromatosis Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A membrane protein and MHC class I antigen. It contains an IMMUNOGLOBULIN C1-SET DOMAIN and interacts with BETA 2-MICROGLOBULIN. It may also regulate the interaction of TRANSFERRIN with the TRANSFERRIN RECEPTOR. Mutations in the HFE gene are associated with cases of FAMILIAL HEMOCHROMATOSIS.
| Descriptor ID |
D000071020
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| MeSH Number(s) |
D12.776.395.550.489.200 D12.776.543.550.439.200 D23.050.301.500.100.363 D23.050.705.552.100.375
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Hemochromatosis Protein".
Below are MeSH descriptors whose meaning is more specific than "Hemochromatosis Protein".
This graph shows the total number of publications written about "Hemochromatosis Protein" by people in this website by year, and whether "Hemochromatosis Protein" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 2 | 2 |
| 2002 | 0 | 1 | 1 |
| 2005 | 0 | 2 | 2 |
| 2007 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2014 | 0 | 2 | 2 |
| 2015 | 0 | 1 | 1 |
| 2019 | 1 | 0 | 1 |
| 2022 | 0 | 1 | 1 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Hemochromatosis Protein" by people in Profiles.
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Rusfertide for the treatment of iron overload in HFE-related haemochromatosis: an open-label, multicentre, proof-of-concept phase 2 trial. Lancet Gastroenterol Hepatol. 2023 12; 8(12):1118-1128.
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Risk of Hepatocellular Carcinoma in Patients with Various HFE Genotypes. Dig Dis Sci. 2023 01; 68(1):312-322.
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HFE H63D Polymorphism and the Risk for Systemic Hypertension, Myocardial Remodeling, and Adverse Cardiovascular Events in the ARIC Study. Hypertension. 2019 01; 73(1):68-74.
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Birth Characteristics and Childhood Leukemia Risk: Correlations With Genetic Markers. J Pediatr Hematol Oncol. 2015 Jul; 37(5):e301-7.
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Adult liver disorders caused by inborn errors of metabolism: review and update. Mol Genet Metab. 2015 Jan; 114(1):1-10.
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Examination of HFE associations with childhood leukemia risk and extension to other iron regulatory genes. Leuk Res. 2014 Sep; 38(9):1055-60.
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Hemochromatosis gene and nonalcoholic fatty liver disease: a systematic review and meta-analysis. J Hepatol. 2011 Nov; 55(5):1079-85.
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HFE C282Y homozygotes have reduced low-density lipoprotein cholesterol: the Atherosclerosis Risk in Communities (ARIC) Study. Transl Res. 2008 Jul; 152(1):3-10.
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Effects of alcohol consumption on iron metabolism in mice with hemochromatosis mutations. Alcohol Clin Exp Res. 2007 Jan; 31(1):138-43.
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Epidemiologic study on HFE C282Y mutation in Azerbaijan. Eur J Haematol. 2005 Feb; 74(2):180-1.