XANDER WEHRENS to Mice, Inbred C57BL
This is a "connection" page, showing publications XANDER WEHRENS has written about Mice, Inbred C57BL.
Connection Strength
1.300
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Multiomic and electrophysiologic analyses reveal that an inherited MRC2 variant causes fibroblast dysfunction and increased atrial fibrillation susceptibility. Am J Physiol Heart Circ Physiol. 2025 Nov 01; 329(5):H1055-H1071.
Score: 0.123
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Determinants of Ca2+ release restitution: Insights from genetically altered animals and mathematical modeling. J Gen Physiol. 2020 11 02; 152(11).
Score: 0.088
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Nuclear localization of a novel calpain-2 mediated junctophilin-2 C-terminal cleavage peptide promotes cardiomyocyte remodeling. Basic Res Cardiol. 2020 06 26; 115(4):49.
Score: 0.086
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Atrial-Specific Gene Delivery Using an Adeno-Associated Viral Vector. Circ Res. 2019 01 18; 124(2):256-262.
Score: 0.078
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Rearrangement of the Protein Phosphatase 1 Interactome During Heart Failure Progression. Circulation. 2018 10 09; 138(15):1569-1581.
Score: 0.076
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In Vivo Ryr2 Editing Corrects Catecholaminergic Polymorphic Ventricular Tachycardia. Circ Res. 2018 Sep 28; 123(8):953-963.
Score: 0.076
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Early effects of Epac depend on the fine-tuning of the sarcoplasmic reticulum Ca2+ handling in cardiomyocytes. J Mol Cell Cardiol. 2018 01; 114:1-9.
Score: 0.071
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SPEG (Striated Muscle Preferentially Expressed Protein Kinase) Is Essential for Cardiac Function by Regulating Junctional Membrane Complex Activity. Circ Res. 2017 Jan 06; 120(1):110-119.
Score: 0.066
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Junctophilin-2 gene therapy rescues heart failure by normalizing RyR2-mediated Ca2+ release. Int J Cardiol. 2016 Dec 15; 225:371-380.
Score: 0.066
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Expression and function of Kv1.1 potassium channels in human atria from patients with atrial fibrillation. Basic Res Cardiol. 2015 Sep; 110(5):505.
Score: 0.061
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Reduced junctional Na+/Ca2+-exchanger activity contributes to sarcoplasmic reticulum Ca2+ leak in junctophilin-2-deficient mice. Am J Physiol Heart Circ Physiol. 2014 Nov 01; 307(9):H1317-26.
Score: 0.057
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Impaired local regulation of ryanodine receptor type 2 by protein phosphatase 1 promotes atrial fibrillation. Cardiovasc Res. 2014 Jul 01; 103(1):178-87.
Score: 0.056
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Junctophilin-2 is necessary for T-tubule maturation during mouse heart development. Cardiovasc Res. 2013 Oct 01; 100(1):44-53.
Score: 0.052
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Ablation of phospholamban rescues reperfusion arrhythmias but exacerbates myocardium infarction in hearts with Ca2+/calmodulin kinase II constitutive phosphorylation of ryanodine receptors. Cardiovasc Res. 2019 03 01; 115(3):556-569.
Score: 0.020
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Protein Phosphatase 2A Regulates Cardiac Na+ Channels. Circ Res. 2019 03; 124(5):737-746.
Score: 0.020
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Ranolazine prevents pressure overload-induced cardiac hypertrophy and heart failure by restoring aberrant Na+ and Ca2+ handling. J Cell Physiol. 2019 07; 234(7):11587-11601.
Score: 0.019
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Calcium-calmodulin-dependent protein kinase mediates the intracellular signalling pathways of cardiac apoptosis in mice with impaired glucose tolerance. J Physiol. 2017 06 15; 595(12):4089-4108.
Score: 0.017
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Methyl-CpG binding-protein 2 function in cholinergic neurons mediates cardiac arrhythmogenesis. Hum Mol Genet. 2016 11 15; 25(22):4983-4995.
Score: 0.017
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Junctophilin-2 in the nanoscale organisation and functional signalling of ryanodine receptor clusters in cardiomyocytes. J Cell Sci. 2016 12 01; 129(23):4388-4398.
Score: 0.017
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Leaky RyR2 channels unleash a brainstem spreading depolarization mechanism of sudden cardiac death. Proc Natl Acad Sci U S A. 2016 08 16; 113(33):E4895-903.
Score: 0.016
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Phospholamban ablation rescues the enhanced propensity to arrhythmias of mice with CaMKII-constitutive phosphorylation of RyR2 at site S2814. J Physiol. 2016 06 01; 594(11):3005-30.
Score: 0.016
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A Single Protein Kinase A or Calmodulin Kinase II Site Does Not Control the Cardiac Pacemaker Ca2+ Clock. Circ Arrhythm Electrophysiol. 2016 Feb; 9(2):e003180.
Score: 0.016
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CaMKIId mediates ?-adrenergic effects on RyR2 phosphorylation and SR Ca(2+) leak and the pathophysiological response to chronic ?-adrenergic stimulation. J Mol Cell Cardiol. 2015 Aug; 85:282-91.
Score: 0.015
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Treatment of cardiac arrhythmias in a mouse model of Rett syndrome with Na+-channel-blocking antiepileptic drugs. Dis Model Mech. 2015 Apr; 8(4):363-71.
Score: 0.015
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Oxidative stress and ca(2+) release events in mouse cardiomyocytes. Biophys J. 2014 Dec 16; 107(12):2815-2827.
Score: 0.015
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Genetic deletion of Rnd3/RhoE results in mouse heart calcium leakage through upregulation of protein kinase A signaling. Circ Res. 2015 Jan 02; 116(1):e1-e10.
Score: 0.014
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Lack of UCP3 does not affect skeletal muscle mitochondrial function under lipid-challenged conditions, but leads to sudden cardiac death. Basic Res Cardiol. 2014; 109(6):447.
Score: 0.014
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Microtubule-mediated defects in junctophilin-2 trafficking contribute to myocyte transverse-tubule remodeling and Ca2+ handling dysfunction in heart failure. Circulation. 2014 Apr 29; 129(17):1742-50.
Score: 0.014
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Ryanodine receptor-mediated calcium leak drives progressive development of an atrial fibrillation substrate in a transgenic mouse model. Circulation. 2014 Mar 25; 129(12):1276-1285.
Score: 0.014
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Oxidized Ca(2+)/calmodulin-dependent protein kinase II triggers atrial fibrillation. Circulation. 2013 Oct 15; 128(16):1748-57.
Score: 0.013
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Critical roles of junctophilin-2 in T-tubule and excitation-contraction coupling maturation during postnatal development. Cardiovasc Res. 2013 Oct 01; 100(1):54-62.
Score: 0.013
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Atrial identity is determined by a COUP-TFII regulatory network. Dev Cell. 2013 May 28; 25(4):417-26.
Score: 0.013
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CaMKII inhibition rescues proarrhythmic phenotypes in the model of human ankyrin-B syndrome. Heart Rhythm. 2012 Dec; 9(12):2034-41.
Score: 0.012
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Circadian rhythms govern cardiac repolarization and arrhythmogenesis. Nature. 2012 Feb 22; 483(7387):96-9.
Score: 0.012
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Pathogenesis of lethal cardiac arrhythmias in Mecp2 mutant mice: implication for therapy in Rett syndrome. Sci Transl Med. 2011 Dec 14; 3(113):113ra125.
Score: 0.012
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Sudden infant death syndrome in mice with an inherited mutation in RyR2. Circ Arrhythm Electrophysiol. 2009 Dec; 2(6):677-85.
Score: 0.010