Header Logo

Connection

XANDER WEHRENS to Arrhythmias, Cardiac

Back to Details
This is a "connection" page, showing publications XANDER WEHRENS has written about Arrhythmias, Cardiac.
XANDER WEHRENS
Connection Strength
11.127
Arrhythmias, Cardiac
  1. Gene Therapy for Inherited Cardiac Arrhythmias. J Cardiovasc Transl Res. 2025 Dec; 18(6):1525-1539.
    View in: PubMed
    Score: 0.700
  2. Immune cells and arrhythmias. Cardiovasc Res. 2025 Apr 29; 121(3):382-395.
    View in: PubMed
    Score: 0.676
  3. In Vivo Cardiac Electrophysiology in Mice: Determination of Atrial and Ventricular Arrhythmic Substrates. Curr Protoc. 2024 Feb; 4(2):e994.
    View in: PubMed
    Score: 0.620
  4. Role of Ca2+ in healthy and pathologic cardiac function: from normal excitation-contraction coupling to mutations that cause inherited arrhythmia. Arch Toxicol. 2023 01; 97(1):73-92.
    View in: PubMed
    Score: 0.566
  5. Genetic basis and molecular biology of cardiac arrhythmias in cardiomyopathies. Cardiovasc Res. 2020 07 15; 116(9):1600-1619.
    View in: PubMed
    Score: 0.485
  6. Targeting pathological leak of ryanodine receptors: preclinical progress and the potential impact on treatments for cardiac arrhythmias and heart failure. Expert Opin Ther Targets. 2020 01; 24(1):25-36.
    View in: PubMed
    Score: 0.468
  7. Mouse Models of Cardiac Arrhythmias. Circ Res. 2018 07 20; 123(3):332-334.
    View in: PubMed
    Score: 0.423
  8. Oxidized CaMKII (Ca2+/Calmodulin-Dependent Protein Kinase II) Is Essential for Ventricular Arrhythmia in a Mouse Model of Duchenne Muscular Dystrophy. Circ Arrhythm Electrophysiol. 2018 04; 11(4):e005682.
    View in: PubMed
    Score: 0.414
  9. Calcium Signaling and Cardiac Arrhythmias. Circ Res. 2017 Jun 09; 120(12):1969-1993.
    View in: PubMed
    Score: 0.391
  10. Junctophilin-2 at the intersection of arrhythmia and pathologic cardiac remodeling. Heart Rhythm. 2016 Mar; 13(3):753-4.
    View in: PubMed
    Score: 0.351
  11. Long-term simulated microgravity causes cardiac RyR2 phosphorylation and arrhythmias in mice. Int J Cardiol. 2014 Oct 20; 176(3):994-1000.
    View in: PubMed
    Score: 0.323
  12. Role of RyR2 phosphorylation in heart failure and arrhythmias: Controversies around ryanodine receptor phosphorylation in cardiac disease. Circ Res. 2014 Apr 11; 114(8):1311-9; discussion 1319.
    View in: PubMed
    Score: 0.314
  13. Enhanced impact of SCN5A mutation associated with long QT syndrome in fetal splice isoform. Heart Rhythm. 2012 Apr; 9(4):598-9.
    View in: PubMed
    Score: 0.267
  14. Targeting ryanodine receptors for anti-arrhythmic therapy. Acta Pharmacol Sin. 2011 Jun; 32(6):749-57.
    View in: PubMed
    Score: 0.258
  15. Ryanodine receptor phosphorylation, calcium/calmodulin-dependent protein kinase II, and life-threatening ventricular arrhythmias. Trends Cardiovasc Med. 2011 Feb; 21(2):48-51.
    View in: PubMed
    Score: 0.252
  16. Ryanodine receptor phosphorylation by calcium/calmodulin-dependent protein kinase II promotes life-threatening ventricular arrhythmias in mice with heart failure. Circulation. 2010 Dec 21; 122(25):2669-79.
    View in: PubMed
    Score: 0.248
  17. CaMKII regulation of the cardiac ryanodine receptor and sarcoplasmic reticulum calcium release. Heart Rhythm. 2011 Feb; 8(2):323-5.
    View in: PubMed
    Score: 0.246
  18. Programmed electrical stimulation in mice. J Vis Exp. 2010 May 26; (39).
    View in: PubMed
    Score: 0.240
  19. Alternative splicing: a key mechanism for ankyrin-B functional diversity? J Mol Cell Cardiol. 2008 Dec; 45(6):709-11.
    View in: PubMed
    Score: 0.214
  20. Sarcoplasmic reticulum calcium leak and cardiac arrhythmias. Biochem Soc Trans. 2007 Nov; 35(Pt 5):952-6.
    View in: PubMed
    Score: 0.201
  21. Mechanisms of human arrhythmia syndromes: abnormal cardiac macromolecular interactions. Physiology (Bethesda). 2007 Oct; 22:342-50.
    View in: PubMed
    Score: 0.200
  22. Structural determinants of potassium channel blockade and drug-induced arrhythmias. Handb Exp Pharmacol. 2006; (171):123-57.
    View in: PubMed
    Score: 0.177
  23. HRS Scientific Documents Methodology Manual: Executive summary. Heart Rhythm. 2025 Aug; 22(8):e538-e543.
    View in: PubMed
    Score: 0.170
  24. Ryanodine receptor-targeted anti-arrhythmic therapy. Ann N Y Acad Sci. 2005 Jun; 1047:366-75.
    View in: PubMed
    Score: 0.170
  25. ATP1A3 Variants, Variably Penetrant Short QT Intervals, and Lethal Ventricular Arrhythmias. JAMA Pediatr. 2025 May 01; 179(5):529-539.
    View in: PubMed
    Score: 0.169
  26. Folate as a potential treatment for lethal ventricular arrhythmias in TANGO2-deficiency disorder. JCI Insight. 2024 06 10; 9(11).
    View in: PubMed
    Score: 0.159
  27. FKBP12.6 deficiency and defective calcium release channel (ryanodine receptor) function linked to exercise-induced sudden cardiac death. Cell. 2003 Jun 27; 113(7):829-40.
    View in: PubMed
    Score: 0.149
  28. Genome Editing and Cardiac Arrhythmias. Cells. 2023 05 11; 12(10).
    View in: PubMed
    Score: 0.147
  29. Paracrine signalling by cardiac calcitonin controls atrial fibrogenesis and arrhythmia. Nature. 2020 11; 587(7834):460-465.
    View in: PubMed
    Score: 0.124
  30. Exercise restores dysregulated gene expression in a mouse model of arrhythmogenic cardiomyopathy. Cardiovasc Res. 2020 05 01; 116(6):1199-1213.
    View in: PubMed
    Score: 0.120
  31. Cardiac dysregulation following intrahippocampal kainate-induced status epilepticus. Sci Rep. 2020 03 04; 10(1):4043.
    View in: PubMed
    Score: 0.118
  32. Ablation of phospholamban rescues reperfusion arrhythmias but exacerbates myocardium infarction in hearts with Ca2+/calmodulin kinase II constitutive phosphorylation of ryanodine receptors. Cardiovasc Res. 2019 03 01; 115(3):556-569.
    View in: PubMed
    Score: 0.110
  33. Protein Phosphatase 2A Regulates Cardiac Na+ Channels. Circ Res. 2019 03; 124(5):737-746.
    View in: PubMed
    Score: 0.110
  34. Early effects of Epac depend on the fine-tuning of the sarcoplasmic reticulum Ca2+ handling in cardiomyocytes. J Mol Cell Cardiol. 2018 01; 114:1-9.
    View in: PubMed
    Score: 0.100
  35. Methyl-CpG binding-protein 2 function in cholinergic neurons mediates cardiac arrhythmogenesis. Hum Mol Genet. 2016 11 15; 25(22):4983-4995.
    View in: PubMed
    Score: 0.094
  36. Reversible redox modifications of ryanodine receptor ameliorate ventricular arrhythmias in the ischemic-reperfused heart. Am J Physiol Heart Circ Physiol. 2016 09 01; 311(3):H713-24.
    View in: PubMed
    Score: 0.092
  37. Phospholamban ablation rescues the enhanced propensity to arrhythmias of mice with CaMKII-constitutive phosphorylation of RyR2 at site S2814. J Physiol. 2016 06 01; 594(11):3005-30.
    View in: PubMed
    Score: 0.089
  38. Cardiac expression of the CREM repressor isoform CREM-Ib?C-X in mice leads to arrhythmogenic alterations in ventricular cardiomyocytes. Basic Res Cardiol. 2016 Mar; 111(2):15.
    View in: PubMed
    Score: 0.089
  39. Loss-of-Function SCN5A Mutations Associated With Sinus Node Dysfunction, Atrial Arrhythmias, and Poor Pacemaker Capture. Circ Arrhythm Electrophysiol. 2015 Oct; 8(5):1105-12.
    View in: PubMed
    Score: 0.085
  40. Treatment of cardiac arrhythmias in a mouse model of Rett syndrome with Na+-channel-blocking antiepileptic drugs. Dis Model Mech. 2015 Apr; 8(4):363-71.
    View in: PubMed
    Score: 0.083
  41. Atrial arrhythmogenesis in catecholaminergic polymorphic ventricular tachycardia--is there a mechanistic link between sarcoplasmic reticulum Ca(2+) leak and re-entry? Acta Physiol (Oxf). 2013 Feb; 207(2):208-11.
    View in: PubMed
    Score: 0.072
  42. Epac2 mediates cardiac ?1-adrenergic-dependent sarcoplasmic reticulum Ca2+ leak and arrhythmia. Circulation. 2013 Feb 26; 127(8):913-22.
    View in: PubMed
    Score: 0.072
  43. CaMKII inhibition rescues proarrhythmic phenotypes in the model of human ankyrin-B syndrome. Heart Rhythm. 2012 Dec; 9(12):2034-41.
    View in: PubMed
    Score: 0.070
  44. Circadian rhythms govern cardiac repolarization and arrhythmogenesis. Nature. 2012 Feb 22; 483(7387):96-9.
    View in: PubMed
    Score: 0.068
  45. Pathogenesis of lethal cardiac arrhythmias in Mecp2 mutant mice: implication for therapy in Rett syndrome. Sci Transl Med. 2011 Dec 14; 3(113):113ra125.
    View in: PubMed
    Score: 0.067
  46. Calcium-calmodulin dependent protein kinase II (CaMKII): a main signal responsible for early reperfusion arrhythmias. J Mol Cell Cardiol. 2011 Dec; 51(6):936-44.
    View in: PubMed
    Score: 0.065
  47. Pitx2 prevents susceptibility to atrial arrhythmias by inhibiting left-sided pacemaker specification. Proc Natl Acad Sci U S A. 2010 May 25; 107(21):9753-8.
    View in: PubMed
    Score: 0.060
  48. Diseases associated with altered ryanodine receptor activity. Subcell Biochem. 2007; 45:273-321.
    View in: PubMed
    Score: 0.047
  49. Stabilization of cardiac ryanodine receptor prevents intracellular calcium leak and arrhythmias. Proc Natl Acad Sci U S A. 2006 May 16; 103(20):7906-10.
    View in: PubMed
    Score: 0.045
  50. Phosphodiesterase 4D deficiency in the ryanodine-receptor complex promotes heart failure and arrhythmias. Cell. 2005 Oct 07; 123(1):25-35.
    View in: PubMed
    Score: 0.044
  51. An improved reporter identifies ruxolitinib as a potent and cardioprotective CaMKII inhibitor. Sci Transl Med. 2023 06 21; 15(701):eabq7839.
    View in: PubMed
    Score: 0.037
  52. A microtubule-connexin-43 regulatory link suppresses arrhythmias and cardiac fibrosis in Duchenne muscular dystrophy mice. Am J Physiol Heart Circ Physiol. 2022 11 01; 323(5):H983-H995.
    View in: PubMed
    Score: 0.035
  53. 2022 HRS expert consensus statement on evaluation and management of arrhythmic risk in neuromuscular disorders. Heart Rhythm. 2022 10; 19(10):e61-e120.
    View in: PubMed
    Score: 0.034
  54. Myocardial disease in failing hearts: defective excitation-contraction coupling. Cold Spring Harb Symp Quant Biol. 2002; 67:533-41.
    View in: PubMed
    Score: 0.034
  55. Novel arrhythmogenic mechanism revealed by a long-QT syndrome mutation in the cardiac Na(+) channel. Circ Res. 2001 Apr 13; 88(7):740-5.
    View in: PubMed
    Score: 0.032
  56. A comparison of electrocardiographic changes during reperfusion of acute myocardial infarction by thrombolysis or percutaneous transluminal coronary angioplasty. Am Heart J. 2000 Mar; 139(3):430-6.
    View in: PubMed
    Score: 0.030
  57. CRISPR -Mediated Expression of the Fetal Scn5a Isoform in Adult Mice Causes Conduction Defects and Arrhythmias. J Am Heart Assoc. 2018 10 02; 7(19):e010393.
    View in: PubMed
    Score: 0.027
  58. Calcium-calmodulin-dependent protein kinase mediates the intracellular signalling pathways of cardiac apoptosis in mice with impaired glucose tolerance. J Physiol. 2017 06 15; 595(12):4089-4108.
    View in: PubMed
    Score: 0.024
  59. Cellular and molecular mechanisms of atrial arrhythmogenesis in patients with paroxysmal atrial fibrillation. Circulation. 2014 Jan 14; 129(2):145-156.
    View in: PubMed
    Score: 0.019
  60. Ryanodine receptor phosphorylation by oxidized CaMKII contributes to the cardiotoxic effects of cardiac glycosides. Cardiovasc Res. 2014 Jan 01; 101(1):165-74.
    View in: PubMed
    Score: 0.019
  61. Calstabin deficiency, ryanodine receptors, and sudden cardiac death. Biochem Biophys Res Commun. 2004 Oct 01; 322(4):1267-79.
    View in: PubMed
    Score: 0.010
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.