InstitutionBaylor College of Medicine
DepartmentDepartment of Pediatrics
Address6701 FANNIN
Houston, TX 77030
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    K23HD040982     (MANDALAKAS, ANNA M)Sep 4, 2001 - Jun 30, 2006
    Cost-effective Screening in International Adoptees
    Role: Principal Investigator

    R01AI076199     (MANDALAKAS, ANNA M)Aug 1, 2007 - Jul 31, 2012
    The Utility of Interferon-Gamma Release Assays in TB-HIV co-infected Children
    Role: Principal Investigator

    R01AI137527     (MANDALAKAS, ANNA M)Jul 1, 2019 - Jun 30, 2023
    Quantifiable stool-based TB PCR to Improve Diagnostics and Treatment Monitoring
    Role: Principal Investigator

    U01GH002278     (MANDALAKAS, ANNA M)Sep 30, 2020 - Sep 29, 2025
    Closing -TB GAPs - for people living with HIV: TB Guidance for Adaptable Patient-Centered Service
    Role: Principal Investigator

    D43TW011547     (MANDALAKAS, ANNA M)Jul 12, 2021 - Mar 31, 2026
    Siyakhula: Growing HIV/TB Research Knowledge for Growing Healthy Kids in Eswatini
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Huang Z, LaCourse SM, Kay AW, Stern J, Escudero JN, Youngquist BM, Zheng W, Vambe D, Dlamini M, Mtetwa G, Cranmer LM, Njuguna I, Wamalwa DC, Maleche-Obimbo E, Catanzaro DG, Lyon CJ, John-Stewart G, DiNardo A, Mandalakas AM, Ning B, Hu TY. CRISPR detection of circulating cell-free Mycobacterium tuberculosis DNA in adults and children, including children with HIV: a molecular diagnostics study. Lancet Microbe. 2022 May 31. PMID: 35659882.
    2. Sibandze DB, Kay A, Dreyer V, Sikhondze W, Dlamini Q, DiNardo A, Mtetwa G, Lukhele B, Vambe D, Lange C, Glenn Dlamini M, Ness T, Mejia R, Kalsdorf B, Heyckendorf J, Kuhns M, Maurer FP, Dlamini S, Maphalala G, Niemann S, Mandalakas A. Rapid molecular diagnostics of tuberculosis resistance by targeted stool sequencing. Genome Med. 2022 May 19; 14(1):52. PMID: 35585607.
      Citations:    Fields:    Translation:HumansCells
    3. Kay AW, Sandoval M, Mtetwa G, Mkhabela M, Ndlovu B, Devezin T, Sikhondze W, Vambe D, Sibanda J, Dube GS, Stevens RH, Lukhele B, Mandalakas AM. Vikela Ekhaya: A Novel, Community-based, Tuberculosis Contact Management Program in a High Burden Setting. Clin Infect Dis. 2022 05 03; 74(9):1631-1638. PMID: 34302733.
      Citations: 2     Fields:    Translation:HumansPHPublic Health
    4. DiNardo AR, Gandhi T, Heyckendorf J, Grimm SL, Rajapakshe K, Nishiguchi T, Reimann M, Kirchner HL, Kahari J, Dlamini Q, Lange C, Goldmann T, Marwitz S, Cirillo JD, Kaufmann SH, Netea MG, van Crevel R, Mandalakas AM, Coarfa C. Gene expression signatures identify biologically and clinically distinct tuberculosis endotypes. Eur Respir J. 2022 Feb 15. PMID: 35169026.
      Citations: 1     Fields:    
    5. Lange C, Kay A, Mandalakas AM. The need for effective drugs for TB prevention: set your goals high, and don´t stop till you get there. Int J Tuberc Lung Dis. 2022 02 01; 26(2):85-88. PMID: 35086616.
      Citations:    Fields:    Translation:Humans
    6. Fennelly KP, Martinez L, Mandalakas AM. Tuberculosis: First in Flight. Am J Respir Crit Care Med. 2022 02 01; 205(3):272-274. PMID: 34905703.
      Citations:    Fields:    Translation:Humans
    7. Kay AW, Rabie H, Maleche-Obimbo E, Sekadde MP, Cotton MF, Mandalakas AM. HIV-Associated Tuberculosis in Children and Adolescents: Evolving Epidemiology, Screening, Prevention and Management Strategies. Pathogens. 2021 Dec 29; 11(1). PMID: 35055981.
      Citations: 1     
    8. Mtetwa G, Anabwani-Richter F, Dlamini N, Dlamini Q, Devezin T, Kay A, DiNardo A, Mandalakas A, Lukhele B. Sterilization of gowns: making the most of a scarce commodity during the COVID-19 pandemic. Public Health Action. 2021 Sep 21; 11(3):112-113. PMID: 34567985.
    9. Lange C, Aaby P, Behr MA, Donald PR, Kaufmann SHE, Netea MG, Mandalakas AM. 100 years of Mycobacterium bovis bacille Calmette-Guérin. Lancet Infect Dis. 2022 01; 22(1):e2-e12. PMID: 34506734.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    10. Heyckendorf J, Marwitz S, Reimann M, Avsar K, DiNardo AR, Günther G, Hoelscher M, Ibraim E, Kalsdorf B, Kaufmann SHE, Kontsevaya I, van Leth F, Mandalakas AM, Maurer FP, Müller M, Nitschkowski D, Olaru ID, Popa C, Rachow A, Rolling T, Rybniker J, Salzer HJF, Sanchez-Carballo P, Schuhmann M, Schaub D, Spinu V, Suárez I, Terhalle E, Unnewehr M, Weiner J, Goldmann T, Lange C. Prediction of anti-tuberculosis treatment duration based on a 22-gene transcriptomic model. Eur Respir J. 2021 09; 58(3). PMID: 33574078.
      Citations: 2     Fields:    Translation:HumansCells
    11. Thivalapill N, Simelane T, Mthethwa N, Dlamini S, Lukhele B, Okello V, Kirchner HL, Mandalakas AM, Kay AW. Transition to Dolutegravir Is Associated With an Increase in the Rate of Body Mass Index Change in a Cohort of Virally Suppressed Adolescents. Clin Infect Dis. 2021 08 02; 73(3):e580-e586. PMID: 33119739.
      Citations: 3     Fields:    Translation:Humans
    12. Ronge L, Sloot R, Du Preez K, Kay AW, Kirchner HL, Grewal HMS, Mandalakas AM, Hesseling AC. The Magnitude of Interferon Gamma Release Assay Responses in Children With Household Tuberculosis Contact Is Associated With Tuberculosis Exposure and Disease Status. Pediatr Infect Dis J. 2021 08 01; 40(8):763-770. PMID: 34050092.
      Citations:    Fields:    Translation:HumansCells
    13. Vonasek B, Ness T, Takwoingi Y, Kay AW, van Wyk SS, Ouellette L, Marais BJ, Steingart KR, Mandalakas AM. Screening tests for active pulmonary tuberculosis in children. Cochrane Database Syst Rev. 2021 06 28; 6:CD013693. PMID: 34180536.
      Citations: 4     Fields:    Translation:HumansPHPublic Health
    14. Jasumback CL, Dlamini Q, Kahari J, Maphalala G, Dlamini MG, Dube GS, DiNardo A, Kirchner HL, Mandalakas A, Kay AW. Laboratory comparison of stool processing methods for Xpert® Ultra. Public Health Action. 2021 Jun 21; 11(2):55-57. PMID: 34159062.
    15. Kontsevaya I, Lange C, Comella-Del-Barrio P, Coarfa C, DiNardo AR, Gillespie SH, Hauptmann M, Leschczyk C, Mandalakas AM, Martinecz A, Merker M, Niemann S, Reimann M, Rzhepishevska O, Schaible UE, Scheu KM, Schurr E, Abel Zur Wiesch P, Heyckendorf J. Perspectives for systems biology in the management of tuberculosis. Eur Respir Rev. 2021 Jun 30; 30(160). PMID: 34039674.
      Citations: 1     Fields:    Translation:Humans
    16. Mandalakas AM, Hesseling AC, Kay A, Du Preez K, Martinez L, Ronge L, DiNardo A, Lange C, Kirchner HL. Tuberculosis prevention in children: a prospective community-based study in South Africa. Eur Respir J. 2021 04; 57(4). PMID: 33122339.
      Citations: 2     Fields:    Translation:Humans
    17. Lange C, Chesov D, Konstantynovska O, Mandalakas AM, Udwadia Z. Sorry for the delay. Clin Microbiol Infect. 2021 07; 27(7):941-943. PMID: 33823271.
      Citations:    Fields:    Translation:HumansCells
    18. Marais BJ, Verkuijl S, Casenghi M, Triasih R, Hesseling AC, Mandalakas AM, Marcy O, Seddon JA, Graham SM, Amanullah F. Paediatric tuberculosis - new advances to close persistent gaps. Int J Infect Dis. 2021 Dec; 113 Suppl 1:S63-S67. PMID: 33716193.
      Citations: 2     Fields:    Translation:Humans
    19. DiNardo AR, Nishiguchi T, Grimm SL, Schlesinger LS, Graviss EA, Cirillo JD, Coarfa C, Mandalakas AM, Heyckendorf J, Kaufmann SHE, Lange C, Netea MG, Van Crevel R. Tuberculosis endotypes to guide stratified host-directed therapy. Med (N Y). 2021 03 12; 2(3):217-232. PMID: 34693385.
      Citations: 2     Translation:HumansCells
    20. Vonasek B, Kay A, Devezin T, Bacha JM, Kazembe P, Dhillon D, Dlamini S, Haq H, Thahane L, Simon K, Matshaba M, Sanders J, Minde M, Wanless S, Nyasulu P, Mandalakas A. Tuberculosis symptom screening for children and adolescents living with HIV in six high HIV/TB burden countries in Africa. AIDS. 2021 01 01; 35(1):73-79. PMID: 33048868.
      Citations: 4     Fields:    Translation:HumansPHPublic Health
    21. Kay AW, Thivalapill N, Skinner D, Dube GS, Dlamini N, Mzileni B, Fuentes P, Ustero P, Adams LV, Mandalakas AM. Predictors of suboptimal adherence to isoniazid preventive therapy among adolescents and children living with HIV. PLoS One. 2020; 15(12):e0243713. PMID: 33332462.
      Citations: 4     Fields:    Translation:Humans
    22. Thivalapill N, Jasumback CL, Perry SH, Dlamini L, Matsenjwa M, Masangane ZT, Mavimbela M, Mthethwa N, Kirchner HL, Mphaya J, Lukhele B, Mandalakas A, Kay AW. Predicting Sexually Transmitted Infections Among HIV+ Adolescents and Young Adults: A Novel Risk Score to Augment Syndromic Management in Eswatini. J Acquir Immune Defic Syndr. 2020 12 15; 85(5):543-552. PMID: 32947446.
      Citations:    Fields:    Translation:HumansPHPublic Health
    23. Mandalakas AM, Kay AW, Bacha JM, Devezin T, Golin R, Simon KR, Dhillon D, Dlamini S, DiNardo A, Matshaba M, Sanders J, Thahane L, Amuge PM, Ahmed S, Sekadde MP, Fida NG, Lukhele B, Chidah N, Damba D, Mhango J, Chodota M, Matsoso M, Kayabu A, Wanless RS, Schutze GE. Tuberculosis among Children and Adolescents at HIV Treatment Centers in Sub-Saharan Africa. Emerg Infect Dis. 2020 12; 26(12). PMID: 33219815.
      Citations: 4     Fields:    Translation:Humans
    24. Gatchalian SR, Agathis NT, Castillo-Carandang NT, Gunter SM, Murray KO, Mandalakas AM. Design and Evaluation of Risk Assessment Tools to Identify Pediatric Tuberculosis Infection in Bohol, the Philippines, a Low-HIV- and High-TB-Burden Setting. Am J Trop Med Hyg. 2020 11; 103(5):1818-1826. PMID: 32975174.
      Citations:    Fields:    Translation:HumansCells
    25. Lange C, Aarnoutse R, Chesov D, van Crevel R, Gillespie SH, Grobbel HP, Kalsdorf B, Kontsevaya I, van Laarhoven A, Nishiguchi T, Mandalakas A, Merker M, Niemann S, Köhler N, Heyckendorf J, Reimann M, Ruhwald M, Sanchez-Carballo P, Schwudke D, Waldow F, DiNardo AR. Perspective for Precision Medicine for Tuberculosis. Front Immunol. 2020; 11:566608. PMID: 33117351.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    26. Kay AW, Ness TE, Martinez L, Mandalakas AM. It Ain't Over Till It's Over: The Triple Threat of COVID-19, TB, and HIV. Am J Trop Med Hyg. 2020 10; 103(4):1348-1349. PMID: 32876009.
      Citations: 1     Fields:    Translation:HumansCellsPHPublic Health
    27. Sandoval M, Swamy P, Kay AW, Alonso PU, Dube GS, Hlophe-Dlamini H, Mandalakas AM. Distinct Risk Factors for Clinical and Bacteriologically Confirmed Tuberculosis among Child Household Contacts in a High-Burden Setting. Am J Trop Med Hyg. 2020 12; 103(6):2506-2509. PMID: 32996456.
      Citations:    Fields:    Translation:HumansPHPublic Health
    28. Kay AW, González Fernández L, Takwoingi Y, Eisenhut M, Detjen AK, Steingart KR, Mandalakas AM. Xpert MTB/RIF and Xpert MTB/RIF Ultra assays for active tuberculosis and rifampicin resistance in children. Cochrane Database Syst Rev. 2020 08 27; 8:CD013359. PMID: 32853411.
      Citations: 20     Fields:    Translation:HumansCells
    29. DiNardo AR, Rajapakshe K, Nishiguchi T, Grimm SL, Mtetwa G, Dlamini Q, Kahari J, Mahapatra S, Kay A, Maphalala G, Mace EM, Makedonas G, Cirillo JD, Netea MG, van Crevel R, Coarfa C, Mandalakas AM. DNA hypermethylation during tuberculosis dampens host immune responsiveness. J Clin Invest. 2020 06 01; 130(6):3113-3123. PMID: 32125282.
      Citations: 13     Fields:    Translation:HumansCells
    30. Martinez L, Cords O, Horsburgh CR, Andrews JR. The risk of tuberculosis in children after close exposure: a systematic review and individual-participant meta-analysis. Lancet. 2020 03 21; 395(10228):973-984. PMID: 32199484.
      Citations: 35     Fields:    Translation:HumansCellsPHPublic Health
    31. Lange C, Dheda K, Chesov D, Mandalakas AM, Udwadia Z, Horsburgh CR. Challenging the management of drug-resistant tuberculosis - Authors' reply. Lancet. 2020 03 07; 395(10226):783-784. PMID: 32145791.
      Citations:    Fields:    Translation:Humans
    32. Jasumback CL, Perry SH, Ness TE, Matsenjwa M, Masangane ZT, Mavimbela M, Mthethwa N, Dlamini L, Mphaya J, Kirchner HL, Mandalakas A, Kay AW. Point-of-Care Testing to Guide Treatment and Estimate Risk Factors for Sexually Transmitted Infections in Adolescents and Young People With Human Immunodeficiency Virus in Eswatini. Open Forum Infect Dis. 2020 Mar; 7(3):ofaa052. PMID: 32190707.
      Citations: 3     
    33. Amanullah F, Bacha JM, Fernandez LG, Mandalakas AM. Quality matters: Redefining child TB care with an emphasis on quality. J Clin Tuberc Other Mycobact Dis. 2019 Dec; 17:100130. PMID: 31788571.
      Citations: 1     
    34. Murray KO, Castillo-Carandang NT, Mandalakas AM, Cruz AT, Leining LM, Gatchalian SR. Prevalence of Tuberculosis in Children After Natural Disasters, Bohol, Philippines. Emerg Infect Dis. 2019 10; 25(10):1884-1892. PMID: 31538561.
      Citations: 2     Fields:    Translation:Humans
    35. Apis V, Landi M, Graham SM, Islam T, Amini J, Sabumi G, Mandalakas AM, Meae T, du Cros P, Shewade HD, Welch H. Outcomes in children treated for tuberculosis with the new dispersible fixed-dose combinations in Port Moresby. Public Health Action. 2019 Sep 21; 9(Suppl 1):S32-S37. PMID: 31579647.
      Citations: 2     
    36. Lange C, Dheda K, Chesov D, Mandalakas AM, Udwadia Z, Horsburgh CR. Management of drug-resistant tuberculosis. Lancet. 2019 09 14; 394(10202):953-966. PMID: 31526739.
      Citations: 38     Fields:    Translation:HumansCells
    37. Zürcher K, Ballif M, Kiertiburanakul S, Chenal H, Yotebieng M, Grinsztejn B, Michael D, Sterling TR, Ngonyani KM, Mandalakas AM, Egger M, Pettit AC, Fenner L. Diagnosis and clinical outcomes of extrapulmonary tuberculosis in antiretroviral therapy programmes in low- and middle-income countries: a multicohort study. J Int AIDS Soc. 2019 09; 22(9):e25392. PMID: 31507083.
      Citations: 7     Fields:    Translation:Humans
    38. Lange C, Aarnoutse RE, Alffenaar JWC, Bothamley G, Brinkmann F, Costa J, Chesov D, van Crevel R, Dedicoat M, Dominguez J, Duarte R, Grobbel HP, Günther G, Guglielmetti L, Heyckendorf J, Kay AW, Kirakosyan O, Kirk O, Koczulla RA, Kudriashov GG, Kuksa L, van Leth F, Magis-Escurra C, Mandalakas AM, Molina-Moya B, Peloquin CA, Reimann M, Rumetshofer R, Schaaf HS, Schön T, Tiberi S, Valda J, Yablonskii PK, Dheda K. Management of patients with multidrug-resistant tuberculosis. Int J Tuberc Lung Dis. 2019 06 01; 23(6):645-662. PMID: 31315696.
      Citations: 17     Fields:    Translation:HumansCells
    39. Martinez L, Lo NC, Cords O, Hill PC, Khan P, Hatherill M, Mandalakas A, Kay A, Croda J, Horsburgh CR, Zar HJ, Andrews JR. Paediatric tuberculosis transmission outside the household: challenging historical paradigms to inform future public health strategies. Lancet Respir Med. 2019 06; 7(6):544-552. PMID: 31078497.
      Citations: 20     Fields:    Translation:HumansCellsPHPublic Health
    40. Keating EM, Sanders J, Ngo K, Mohapi EQ, Mandalakas AM. Development of a Tool for Health Screening and Assessment in Orphanages in Lesotho. Am J Trop Med Hyg. 2019 05; 100(5):1290-1293. PMID: 30915954.
      Citations: 1     Fields:    Translation:HumansPHPublic Health
    41. Said K, Hella J, Ruzegea M, Solanki R, Chiryamkubi M, Mhimbira F, Ritz N, Schindler C, Mandalakas AM, Manji K, Tanner M, Utzinger J, Fenner L. Immunologic-based Diagnosis of Latent Tuberculosis Among Children Younger Than 5 Years of Age Exposed and Unexposed to Tuberculosis in Tanzania. Pediatr Infect Dis J. 2019 04; 38(4):333-339. PMID: 30882720.
      Citations: 4     Fields:    Translation:Humans
    42. Kay AW, DiNardo AR, Dlamini Q, Kahari J, Mndzebele T, Mtetwa G, Ustero P, Maphalala G, Mandalakas AM. Evaluation of the QuantiFERON-Tuberculosis Gold Plus Assay in Children with Tuberculosis Disease or Following Household Exposure to Tuberculosis. Am J Trop Med Hyg. 2019 03; 100(3):540-543. PMID: 30675853.
      Citations: 8     Fields:    Translation:HumansCells
    43. Kay A, Garcia-Prats AJ, Mandalakas AM. HIV-associated pediatric tuberculosis: prevention, diagnosis and treatment. Curr Opin HIV AIDS. 2018 11; 13(6):501-506. PMID: 30286040.
      Citations: 2     Fields:    Translation:HumansCells
    44. Cranmer LM, Draper HR, Mandalakas AM, Kim S, McSherry G, Krezinski E, Coetzee J, Mitchell C, Nachman S, van der Linde M, Cotton MF, Hesseling AC. High Incidence of Tuberculosis Infection in HIV-exposed Children Exiting an Isoniazid Preventive Therapy Trial. Pediatr Infect Dis J. 2018 10; 37(10):e254-e256. PMID: 29462104.
      Citations: 4     Fields:    Translation:HumansCTClinical Trials
    45. DiNardo AR, Nishiguchi T, Mace EM, Rajapakshe K, Mtetwa G, Kay A, Maphalala G, Secor WE, Mejia R, Orange JS, Coarfa C, Bhalla KN, Graviss EA, Mandalakas AM, Makedonas G. Schistosomiasis Induces Persistent DNA Methylation and Tuberculosis-Specific Immune Changes. J Immunol. 2018 07 01; 201(1):124-133. PMID: 29752313.
      Citations: 18     Fields:    Translation:HumansAnimalsCells
    46. DiNardo AR, Kay AW, Maphalala G, Harris NM, Fung C, Mtetwa G, Ustero P, Dlamini S, Ha N, Graviss EA, Mejia R, Mandalakas AM. Diagnostic and Treatment Monitoring Potential of A Stool-Based Quantitative Polymerase Chain Reaction Assay for Pulmonary Tuberculosis. Am J Trop Med Hyg. 2018 08; 99(2):310-316. PMID: 29692304.
      Citations: 10     Fields:    Translation:HumansCells
    47. Mandalakas AM, Highsmith HY, Harris NM, Pawlicka A, Kirchner HL. T-SPOT.TB Performance in Routine Pediatric Practice in a Low TB Burden Setting. Pediatr Infect Dis J. 2018 04; 37(4):292-297. PMID: 29140933.
      Citations: 3     Fields:    Translation:Humans
    48. Brunetti M, Rajasekharan S, Ustero P, Ngo K, Sikhondze W, Mzileni B, Mandalakas A, Kay AW. Leveraging tuberculosis case relative locations to enhance case detection and linkage to care in Swaziland. Glob Health Res Policy. 2018; 3:3. PMID: 29445773.
      Citations: 1     Fields:    
    49. Golla V, Snow K, Mandalakas AM, Schaaf HS, Du Preez K, Hesseling AC, Seddon JA. Correction to: The impact of drug resistance on the risk of tuberculosis infection and disease in child household contacts: a cross sectional study. BMC Infect Dis. 2017 11 07; 17(1):713. PMID: 29115944.
      Citations:    Fields:    
    50. Said K, Hella J, Knopp S, Nassoro T, Shija N, Aziz F, Mhimbira F, Schindler C, Mwingira U, Mandalakas AM, Manji K, Tanner M, Utzinger J, Fenner L. Schistosoma, other helminth infections, and associated risk factors in preschool-aged children in urban Tanzania. PLoS Negl Trop Dis. 2017 Nov; 11(11):e0006017. PMID: 29108003.
      Citations: 8     Fields:    Translation:HumansAnimals
    51. Golla V, Snow K, Mandalakas AM, Schaaf HS, Du Preez K, Hesseling AC, Seddon JA. The impact of drug resistance on the risk of tuberculosis infection and disease in child household contacts: a cross sectional study. BMC Infect Dis. 2017 08 29; 17(1):593. PMID: 28851285.
      Citations: 7     Fields:    Translation:HumansCellsPHPublic Health
    52. Mandalakas AM, Cobelens F. Tuberculosis-making predictions, especially about the future. Lancet Infect Dis. 2017 11; 17(11):1106-1107. PMID: 28827143.
      Citations:    Fields:    Translation:Humans
    53. Szkwarko D, Hirsch-Moverman Y, Du Plessis L, Du Preez K, Carr C, Mandalakas AM. Child contact management in high tuberculosis burden countries: A mixed-methods systematic review. PLoS One. 2017; 12(8):e0182185. PMID: 28763500.
      Citations: 42     Fields:    Translation:HumansPHPublic Health
    54. Ustero PA, Kay AW, Ngo K, Golin R, Tsabedze B, Mzileni B, Glickman J, Wisile Xaba M, Mavimbela G, Mandalakas AM. School and household tuberculosis contact investigations in Swaziland: Active TB case finding in a high HIV/TB burden setting. PLoS One. 2017; 12(6):e0178873. PMID: 28582435.
      Citations: 9     Fields:    Translation:HumansPHPublic Health
    55. Carlucci JG, Blevins Peratikos M, Kipp AM, Lindegren ML, Du QT, Renner L, Reubenson G, Ssali J, Yotebieng M, Mandalakas AM, Davies MA, Ballif M, Fenner L, Pettit AC. Tuberculosis Treatment Outcomes Among HIV/TB-Coinfected Children in the International Epidemiology Databases to Evaluate AIDS (IeDEA) Network. J Acquir Immune Defic Syndr. 2017 Jun 01; 75(2):156-163. PMID: 28234689.
      Citations: 13     Fields:    Translation:Humans
    56. Bacha JM, Ngo K, Clowes P, Draper HR, Ntinginya EN, DiNardo A, Mangu C, Sabi I, Mtafya B, Mandalakas AM. Why being an expert - despite xpert -remains crucial for children in high TB burden settings. BMC Infect Dis. 2017 02 06; 17(1):123. PMID: 28166728.
      Citations: 12     Fields:    Translation:HumansCells
    57. Van der Zalm MM, van Soelen N, Mandalakas AM, Jacobsen M, Detjen AK, Marx FM, Grewal HM, Cotton MF, Walzl G, Hesseling AC. Re: "It May Be Too Early to Try to Prove the Effect of Deworming on Tuberculin Reactivity". Pediatr Infect Dis J. 2017 02; 36(2):241-242. PMID: 28079838.
      Citations:    Fields:    Translation:Humans
    58. Mandalakas AM, Ngo K, Alonso Ustero P, Golin R, Anabwani F, Mzileni B, Sikhondze W, Stevens R. BUTIMBA: Intensifying the Hunt for Child TB in Swaziland through Household Contact Tracing. PLoS One. 2017; 12(1):e0169769. PMID: 28107473.
      Citations: 14     Fields:    Translation:HumansPHPublic Health
    59. DiNardo AR, Detjen A, Ustero P, Ngo K, Bacha J, Mandalakas AM. Culture is an imperfect and heterogeneous reference standard in pediatric tuberculosis. Tuberculosis (Edinb). 2016 12; 101S:S105-S108. PMID: 27727131.
      Citations: 14     Fields:    Translation:HumansCells
    60. Fox GJ, Schaaf HS, Mandalakas A, Chiappini E, Zumla A, Marais BJ. Preventing the spread of multidrug-resistant tuberculosis and protecting contacts of infectious cases. Clin Microbiol Infect. 2017 Mar; 23(3):147-153. PMID: 27592087.
      Citations: 18     Fields:    Translation:HumansPHPublic Health
    61. Van der Zalm MM, van Soelen N, Mandalakas AM, Jacobsen M, Detjen AK, Marx FM, Grewal HM, Cotton MF, Walzl G, Hesseling AC. The Effect of Deworming on Tests of Tuberculosis Infection in Children With Recent Tuberculosis Exposure: A Randomized Controlled Trial. Pediatr Infect Dis J. 2016 06; 35(6):622-7. PMID: 26933841.
      Citations: 8     Fields:    Translation:HumansAnimals
    62. DiNardo AR, Mace EM, Lesteberg K, Cirillo JD, Mandalakas AM, Graviss EA, Orange JS, Makedonas G. Schistosome Soluble Egg Antigen Decreases Mycobacterium tuberculosis-Specific CD4+ T-Cell Effector Function With Concomitant Arrest of Macrophage Phago-Lysosome Maturation. J Infect Dis. 2016 08 01; 214(3):479-88. PMID: 27389351.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    63. DiNardo AR, Mandalakas AM, Maphalala G, Mtetwa G, Mndzebele T, Ustero P, Hlatshwayo M, Mace EM, Orange JS, Makedonas G. HIV Progression Perturbs the Balance of the Cell-Mediated and Anti-Inflammatory Adaptive and Innate Mycobacterial Immune Response. Mediators Inflamm. 2016; 2016:1478340. PMID: 27006526.
      Citations: 3     Fields:    Translation:HumansCells
    64. DiNardo AR, Lange C, Mandalakas AM. Editorial Commentary: 1, 2, 3 (Years)??…??and You're Out: The End of a 123-year Historic Era. Clin Infect Dis. 2016 May 01; 62(9):1089-91. PMID: 26839384.
      Citations: 1     Fields:    Translation:HumansCells
    65. Lange C, Mandalakas AM, Kalsdorf B, Denkinger CM, Sester M. Clinical Application of Interferon-? Release Assays for the Prevention of Tuberculosis in Countries with Low Incidence. Pathog Immun. 2016; 1(2):308-329. PMID: 28217762.
      Citations: 6     
    66. DiNardo AR, Hahn A, Leyden J, Stager C, Jo Baron E, Graviss EA, Mandalakas AM, Guy E. Use of string test and stool specimens to diagnose pulmonary tuberculosis. Int J Infect Dis. 2015 Dec; 41:50-52. PMID: 26523638.
      Citations: 6     Fields:    Translation:HumansCells
    67. Graham SM, Cuevas LE, Jean-Philippe P, Browning R, Casenghi M, Detjen AK, Gnanashanmugam D, Hesseling AC, Kampmann B, Mandalakas A, Marais BJ, Schito M, Spiegel HM, Starke JR, Worrell C, Zar HJ. Clinical Case Definitions for Classification of Intrathoracic Tuberculosis in Children: An Update. Clin Infect Dis. 2015 Oct 15; 61Suppl 3:S179-87. PMID: 26409281.
      Citations: 75     Fields:    Translation:Humans
    68. Priya Dhar C, Elena Gonzalez B, Dragga T, Bothe D, Mandalakas AM. Testing International Adoptees for Tuberculosis. Pediatr Infect Dis J. 2015 Oct; 34(10):1138-9. PMID: 26367807.
      Citations: 1     Fields:    Translation:HumansPHPublic Health
    69. Wiseman CA, Mandalakas AM, Kirchner HL, Gie RP, Schaaf HS, Walters E, Hesseling AC. Novel application of NIH case definitions in a paediatric tuberculosis contact investigation study. Int J Tuberc Lung Dis. 2015 Apr; 19(4):446-53. PMID: 25860001.
      Citations: 9     Fields:    Translation:Humans
    70. Mandalakas AM, Kirchner HL, Walzl G, Gie RP, Schaaf HS, Cotton MF, Grewal HM, Hesseling AC. Optimizing the detection of recent tuberculosis infection in children in a high tuberculosis-HIV burden setting. Am J Respir Crit Care Med. 2015 Apr 01; 191(7):820-30. PMID: 25622087.
      Citations: 20     Fields:    Translation:HumansCellsPHPublic Health
    71. Detjen AK, DiNardo AR, Leyden J, Steingart KR, Menzies D, Schiller I, Dendukuri N, Mandalakas AM. Xpert MTB/RIF assay for the diagnosis of pulmonary tuberculosis in children: a systematic review and meta-analysis. Lancet Respir Med. 2015 Jun; 3(6):451-61. PMID: 25812968.
      Citations: 105     Fields:    Translation:Humans
    72. Carlucci JG, Jin L, Sanders JE, Mohapi EQ, Mandalakas AM. Development of tuberculosis infection control guidelines in a pediatric HIV clinic in sub-Saharan Africa. Public Health Action. 2015 Mar 21; 5(1):2-5. PMID: 26400595.
      Citations: 1     
    73. Musuuza JS, Singer ME, Mandalakas AM, Katamba A. Key actors' perspectives on cost-effectiveness analysis in Uganda: a cross-sectional survey. BMC Health Serv Res. 2014 Nov 04; 14:539. PMID: 25363234.
      Citations: 3     Fields:    Translation:Humans
    74. Ballif M, Renner L, Claude Dusingize J, Leroy V, Ayaya S, Wools-Kaloustian K, Cortes CP, McGowan CC, Graber C, Mandalakas AM, Mofenson LM, Egger M, Kumara Wati KD, Nallusamy R, Reubenson G, Davies MA, Fenner L. Tuberculosis in Pediatric Antiretroviral Therapy Programs in Low- and Middle-Income Countries: Diagnosis and Screening Practices. J Pediatric Infect Dis Soc. 2015 Mar; 4(1):30-8. PMID: 26407355.
      Citations: 9     Fields:    Translation:HumansCells
    75. van Soelen N, du Preez K, van Wyk SS, Mandalakas AM, Enarson DA, Reid AJ, Hesseling AC. Does an isoniazid prophylaxis register improve tuberculosis contact management in South African children? PLoS One. 2013; 8(12):e80803. PMID: 24339884.
      Citations: 13     Fields:    Translation:Humans
    76. Skinner D, Hesseling AC, Francis C, Mandalakas AM. It's hard work, but it's worth it: the task of keeping children adherent to isoniazid preventive therapy. Public Health Action. 2013 Sep 21; 3(3):191-8. PMID: 26393028.
      Citations: 12     
    77. Cruz AT, Ahmed A, Mandalakas AM, Starke JR. Treatment of Latent Tuberculosis Infection in Children. J Pediatric Infect Dis Soc. 2013 Sep; 2(3):248-58. PMID: 26619479.
      Citations: 6     Fields:    
    78. Chegou NN, Detjen AK, Thiart L, Walters E, Mandalakas AM, Hesseling AC, Walzl G. Utility of host markers detected in Quantiferon supernatants for the diagnosis of tuberculosis in children in a high-burden setting. PLoS One. 2013; 8(5):e64226. PMID: 23691173.
      Citations: 29     Fields:    Translation:Humans
    79. Mandalakas AM, van Wyk S, Kirchner HL, Walzl G, Cotton M, Rabie H, Kriel B, Gie RP, Schaaf HS, Hesseling AC. Detecting tuberculosis infection in HIV-infected children: a study of diagnostic accuracy, confounding and interaction. Pediatr Infect Dis J. 2013 Mar; 32(3):e111-8. PMID: 23190784.
      Citations: 17     Fields:    Translation:HumansCells
    80. Skinner D, Mandalakas AM. Pasting together the preventive therapy puzzle. Int J Tuberc Lung Dis. 2013 Feb; 17(2):175-7. PMID: 23211672.
      Citations: 8     Fields:    Translation:HumansPHPublic Health
    81. Cruz AT, Mandalakas AM, Starke JR. Childhood tuberculosis: a preventable disease not being prevented. Pediatrics. 2012 Dec; 130(6):e1672-3. PMID: 23184112.
      Citations: 1     Fields:    Translation:Humans
    82. van Soelen N, Mandalakas AM, Kirchner HL, Walzl G, Grewal HM, Jacobsen M, Hesseling AC. Effect of Ascaris Lumbricoides specific IgE on tuberculin skin test responses in children in a high-burden setting: a cross-sectional community-based study. BMC Infect Dis. 2012 Sep 11; 12:211. PMID: 22966931.
      Citations: 12     Fields:    Translation:HumansAnimals
    83. Mandalakas AM, Hesseling AC, Gie RP, Schaaf HS, Marais BJ, Sinanovic E. Modelling the cost-effectiveness of strategies to prevent tuberculosis in child contacts in a high-burden setting. Thorax. 2013 Mar; 68(3):247-55. PMID: 22717944.
      Citations: 31     Fields:    Translation:Humans
    84. Mandalakas AM, Kirchner HL, Lombard C, Walzl G, Grewal HM, Gie RP, Hesseling AC. Well-quantified tuberculosis exposure is a reliable surrogate measure of tuberculosis infection. Int J Tuberc Lung Dis. 2012 Aug; 16(8):1033-9. PMID: 22692027.
      Citations: 44     Fields:    Translation:HumansCellsPHPublic Health
    85. Cuevas LE, Browning R, Bossuyt P, Casenghi M, Cotton MF, Cruz AT, Dodd LE, Drobniewski F, Gale M, Graham SM, Grzemska M, Heinrich N, Hesseling AC, Huebner R, Jean-Philippe P, Kabra SK, Kampmann B, Lewinsohn D, Li M, Lienhardt C, Mandalakas AM, Marais BJ, Menzies HJ, Montepiedra G, Mwansambo C, Oberhelman R, Palumbo P, Russek-Cohen E, Shapiro DE, Smith B, Soto-Castellares G, Starke JR, Swaminathan S, Wingfield C, Worrell C. Evaluation of tuberculosis diagnostics in children: 2. Methodological issues for conducting and reporting research evaluations of tuberculosis diagnostics for intrathoracic tuberculosis in children. Consensus from an expert panel. J Infect Dis. 2012 May 15; 205 Suppl 2:S209-15. PMID: 22476719.
      Citations: 44     Fields:    Translation:Humans
    86. Van Wyk SS, Mandalakas AM, Enarson DA, Gie RP, Beyers N, Hesseling AC. Tuberculosis contact investigation in a high-burden setting: house or household? Int J Tuberc Lung Dis. 2012 Feb; 16(2):157-62. PMID: 22236914.
      Citations: 14     Fields:    Translation:HumansPHPublic Health
    87. Hesseling AC, Mandalakas AM. Interferon-gamma release assays for childhood tuberculosis: what does the future hold? Int J Tuberc Lung Dis. 2011 Nov; 15(11):1423-4. PMID: 22008752.
      Citations:    Fields:    Translation:HumansCells
    88. du Preez K, Mandalakas AM, Kirchner HL, Grewal HM, Schaaf HS, van Wyk SS, Hesseling AC. Environmental tobacco smoke exposure increases Mycobacterium tuberculosis infection risk in children. Int J Tuberc Lung Dis. 2011 Nov; 15(11):1490-6, i. PMID: 22008762.
      Citations: 17     Fields:    Translation:HumansCellsPHPublic Health
    89. Mandalakas AM, Detjen AK, Hesseling AC. Can we accurately diagnose tuberculosis infection in children? Pediatr Infect Dis J. 2011 Sep; 30(9):817-8. PMID: 21849864.
      Citations: 5     Fields:    Translation:HumansCells
    90. Mandalakas AM, Detjen AK, Hesseling AC, Benedetti A, Menzies D. Interferon-gamma release assays and childhood tuberculosis: systematic review and meta-analysis. Int J Tuberc Lung Dis. 2011 Aug; 15(8):1018-32. PMID: 21669030.
      Citations: 73     Fields:    Translation:HumansCells
    91. van Wyk SS, Reid AJ, Mandalakas AM, Enarson DA, Beyers N, Morrison J, Hesseling AC. Operational challenges in managing Isoniazid Preventive Therapy in child contacts: a high-burden setting perspective. BMC Public Health. 2011 Jul 08; 11:544. PMID: 21740580.
      Citations: 28     Fields:    Translation:Humans
    92. Duncan B, Mandalakas A, Staton D, Anders B, Kurbasic M, Nakakeeto M, Mustafa G, Reyes A, Evangelista D. Child healthcare workers in resource-limited areas improve health with innovative low-cost projects. J Trop Pediatr. 2012 Apr; 58(2):120-4. PMID: 21652575.
      Citations:    Fields:    Translation:HumansPHPublic Health
    93. Mandalakas AM, Menzies D. Is screening immigrants for latent tuberculosis cost-effective? Lancet Infect Dis. 2011 Jun; 11(6):418-9. PMID: 21616450.
      Citations: 3     Fields:    Translation:HumansPHPublic Health
    94. George SA, Ko CA, Kirchner HL, Starke JR, Dragga TA, Mandalakas AM. The role of chest radiographs and tuberculin skin tests in tuberculosis screening of internationally adopted children. Pediatr Infect Dis J. 2011 May; 30(5):387-91. PMID: 21076362.
      Citations: 4     Fields:    Translation:HumansPHPublic Health
    95. Park H, Bothe D, Holsinger E, Kirchner HL, Olness K, Mandalakas A. The impact of nutritional status and longitudinal recovery of motor and cognitive milestones in internationally adopted children. Int J Environ Res Public Health. 2011 01; 8(1):105-16. PMID: 21318018.
      Citations: 6     Fields:    Translation:Humans
    96. Du Preez K, Hesseling AC, Mandalakas AM, Marais BJ, Schaaf HS. Opportunities for chemoprophylaxis in children with culture-confirmed tuberculosis. Ann Trop Paediatr. 2011; 31(4):301-10. PMID: 22041464.
      Citations: 13     Fields:    Translation:Humans
    97. Hesseling AC, Marais BJ, Kirchner HL, Mandalakas AM, Brittle W, Victor TC, Warren RM, Schaaf HS. Mycobacterial genotype is associated with disease phenotype in children. Int J Tuberc Lung Dis. 2010 Oct; 14(10):1252-8. PMID: 20843415.
      Citations: 14     Fields:    Translation:HumansCells
    98. Van Wyk SS, Hamade H, Hesseling AC, Beyers N, Enarson DA, Mandalakas AM. Recording isoniazid preventive therapy delivery to children: operational challenges. Int J Tuberc Lung Dis. 2010 May; 14(5):650-3. PMID: 20392361.
      Citations: 24     Fields:    Translation:Humans
    99. Yeo KT, Zhu X, Kirchner HL, LaBeaud AD, Mandalakas A. Candida skin testing is a poor adjunct to tuberculin skin testing in international adoptees. Pediatr Infect Dis J. 2009 Nov; 28(11):1020-1. PMID: 19820428.
      Citations:    Fields:    Translation:Humans
    100. Verla-Tebit E, Zhu X, Holsinger E, Mandalakas AM. Predictive value of immunization records and risk factors for immunization failure in internationally adopted children. Arch Pediatr Adolesc Med. 2009 May; 163(5):473-9. PMID: 19414695.
      Citations: 7     Fields:    Translation:HumansPHPublic Health
    101. Hesseling AC, Gie RP, Mandalakas AM. The predictive value of the ELISpot-based interferon-gamma-release assay for tuberculosis disease. Ann Intern Med. 2009 Mar 17; 150(6):428-9; author reply 429-30. PMID: 19293083.
      Citations:    Fields:    Translation:HumansCells
    102. Mandalakas AM, Chandawarkar A, Holsinger E. Global child health fellowship programs in demand. Pediatrics. 2008 Dec; 122(6):1417-8; author reply 1418. PMID: 19047273.
      Citations: 1     Fields:    Translation:Humans
    103. Mandalakas AM, Kirchner HL, Zhu X, Yeo KT, Starke JR. Interpretation of repeat tuberculin skin testing in international adoptees: conversions or boosting. Pediatr Infect Dis J. 2008 Oct; 27(10):913-9. PMID: 18776820.
      Citations: 6     Fields:    Translation:HumansCells
    104. Hesseling AC, Mandalakas AM, Kirchner HL, Chegou NN, Marais BJ, Stanley K, Zhu X, Black G, Beyers N, Walzl G. Highly discordant T cell responses in individuals with recent exposure to household tuberculosis. Thorax. 2009 Oct; 64(10):840-6. PMID: 18682523.
      Citations: 30     Fields:    Translation:HumansCells
    105. LaBeaud AD, Gorman AM, Koonce J, Kippes C, McLeod J, Lynch J, Gallagher T, King CH, Mandalakas AM. Rapid GIS-based profiling of West Nile virus transmission: defining environmental factors associated with an urban-suburban outbreak in Northeast Ohio, USA. Geospat Health. 2008 May; 2(2):215-25. PMID: 18686270.
      Citations: 16     Fields:    Translation:HumansCellsPHPublic Health
    106. Mandalakas AM, Hesseling AC, Chegou NN, Kirchner HL, Zhu X, Marais BJ, Black GF, Beyers N, Walzl G. High level of discordant IGRA results in HIV-infected adults and children. Int J Tuberc Lung Dis. 2008 Apr; 12(4):417-23. PMID: 18371268.
      Citations: 40     Fields:    Translation:HumansCells
    107. Mandalakas AM, Kirchner HL, Iverson S, Chesney M, Spencer MJ, Sidler A, Johnson D. Predictors of Mycobacterium tuberculosis infection in international adoptees. Pediatrics. 2007 Sep; 120(3):e610-6. PMID: 17766501.
      Citations: 3     Fields:    Translation:HumansCells
    108. LaBeaud AD, Kile JR, Kippes C, King CH, Mandalakas AM. Exposure to West Nile virus during the 2002 epidemic in Cuyahoga County, Ohio: a comparison of pediatric and adult behaviors. Public Health Rep. 2007 May-Jun; 122(3):356-61. PMID: 17518307.
      Citations: 5     Fields:    Translation:HumansCellsPHPublic Health
    109. LaBeaud AD, Lisgaris MV, King CH, Mandalakas AM. Pediatric West Nile virus infection: neurologic disease presentations during the 2002 epidemic in Cuyahoga County, Ohio. Pediatr Infect Dis J. 2006 Aug; 25(8):751-3. PMID: 16874181.
      Citations: 5     Fields:    Translation:Humans
    110. Mandalakas AM, Kippes C, Sedransk J, Kile JR, Garg A, McLeod J, Berry RL, Marfin AA. West Nile virus epidemic, northeast Ohio, 2002. Emerg Infect Dis. 2005 Nov; 11(11):1774-7. PMID: 16318737.
      Citations: 16     Fields:    Translation:HumansCellsPHPublic Health
    111. Mandalakas AM, Starke JR. Current concepts of childhood tuberculosis. Semin Pediatr Infect Dis. 2005 Apr; 16(2):93-104. PMID: 15825140.
      Citations: 27     Fields:    Translation:HumansCellsPHPublic Health
    112. Mandalakas AM, Starke JR. Tuberculosis screening in immigrant children. Pediatr Infect Dis J. 2004 Jan; 23(1):71-2. PMID: 14743051.
      Citations:    Fields:    Translation:HumansPHPublic Health
    113. Torjesen K, Mandalakas A, Kahn R, Duncan B. International child health electives for pediatric residents. Arch Pediatr Adolesc Med. 1999 Dec; 153(12):1297-302. PMID: 10591310.
      Citations: 23     Fields:    Translation:Humans
    114. Mandalakas AM, Guay L, Musoke P, Carroll-Pankhurst C, Olness KN. Human immunodeficiency virus status and delayed-type hypersensitivity skin testing in Ugandan children. Pediatrics. 1999 Feb; 103(2):E21. PMID: 9925867.
      Citations: 1     Fields:    Translation:HumansCells
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