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ANNA MARIA MANDALAKAS

TitleProfessor
InstitutionBaylor College of Medicine
DepartmentDepartment of Pediatrics
DivisionPediatrics-Global Immigrant Health
AddressOne Baylor Plaza
Houston TX 77030
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    Collapse Overview 
    Collapse keywords
    Tuberculosis
    Latent Tuberculosis Infection
    Tuberculin Skin Test
    Interferon Gamma Release Assays
    Contact Tracing
    Diagnostics
    Preventive Therapy
    HIV
    Adoption


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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. DiNardo AR, Kay AW, Maphalala G, Harris NM, Fung C, Mtetwa G, Ustero P, Dlamini S, Ha N, Graviss EA, Mejia R, Mandalakas AM. Diagnostic and Treatment Monitoring Potential of A Stool-Based Quantitative Polymerase Chain Reaction Assay for Pulmonary Tuberculosis. Am J Trop Med Hyg. 2018 Apr 23. PMID: 29692304.
      View in: PubMed
    2. Mandalakas AM, Highsmith HY, Harris NM, Pawlicka A, Kirchner HL. T-SPOT.TB Performance in Routine Pediatric Practice in a Low TB Burden Setting. Pediatr Infect Dis J. 2018 Apr; 37(4):292-297. PMID: 29140933.
      View in: PubMed
    3. Cranmer LM, Draper HR, Mandalakas AM, Kim S, McSherry G, Krezinski E, Coetzee J, Mitchell C, Nachman S, van der Linde M, Cotton MF, Hesseling AC. High Incidence of Tuberculosis Infection in HIV-Exposed Children Exiting an Isoniazid Preventive Therapy Trial. Pediatr Infect Dis J. 2018 Feb 16. PMID: 29462104.
      View in: PubMed
    4. Brunetti M, Rajasekharan S, Ustero P, Ngo K, Sikhondze W, Mzileni B, Mandalakas A, Kay AW. Leveraging tuberculosis case relative locations to enhance case detection and linkage to care in Swaziland. Glob Health Res Policy. 2018; 3:3. PMID: 29445773.
      View in: PubMed
    5. Golla V, Snow K, Mandalakas AM, Schaaf HS, Du Preez K, Hesseling AC, Seddon JA. Correction to: The impact of drug resistance on the risk of tuberculosis infection and disease in child household contacts: a cross sectional study. BMC Infect Dis. 2017 Nov 07; 17(1):713. PMID: 29115944.
      View in: PubMed
    6. Said K, Hella J, Knopp S, Nassoro T, Shija N, Aziz F, Mhimbira F, Schindler C, Mwingira U, Mandalakas AM, Manji K, Tanner M, Utzinger J, Fenner L. Schistosoma, other helminth infections, and associated risk factors in preschool-aged children in urban Tanzania. PLoS Negl Trop Dis. 2017 Nov; 11(11):e0006017. PMID: 29108003.
      View in: PubMed
    7. Golla V, Snow K, Mandalakas AM, Schaaf HS, Du Preez K, Hesseling AC, Seddon JA. The impact of drug resistance on the risk of tuberculosis infection and disease in child household contacts: a cross sectional study. BMC Infect Dis. 2017 08 29; 17(1):593. PMID: 28851285.
      View in: PubMed
    8. Mandalakas AM, Cobelens F. Tuberculosis-making predictions, especially about the future. Lancet Infect Dis. 2017 Nov; 17(11):1106-1107. PMID: 28827143.
      View in: PubMed
    9. Szkwarko D, Hirsch-Moverman Y, Du Plessis L, Du Preez K, Carr C, Mandalakas AM. Child contact management in high tuberculosis burden countries: A mixed-methods systematic review. PLoS One. 2017; 12(8):e0182185. PMID: 28763500.
      View in: PubMed
    10. Ustero PA, Kay AW, Ngo K, Golin R, Tsabedze B, Mzileni B, Glickman J, Wisile Xaba M, Mavimbela G, Mandalakas AM. School and household tuberculosis contact investigations in Swaziland: Active TB case finding in a high HIV/TB burden setting. PLoS One. 2017; 12(6):e0178873. PMID: 28582435.
      View in: PubMed
    11. Carlucci JG, Blevins M, Kipp AM, Lindegren ML, Du QT, Renner L, Reubenson G, Ssali J, Yotebieng M, Mandalakas AM, Davies MA, Ballif M, Fenner L, Pettit AC. Tuberculosis Treatment Outcomes among HIV/TB Co-Infected Children in the International Epidemiology Databases to Evaluate AIDS (IeDEA) Network. J Acquir Immune Defic Syndr. 2017 Feb 20. PMID: 28234689.
      View in: PubMed
    12. Bacha JM, Ngo K, Clowes P, Draper HR, Ntinginya EN, DiNardo A, Mangu C, Sabi I, Mtafya B, Mandalakas AM. Why being an expert - despite xpert -remains crucial for children in high TB burden settings. BMC Infect Dis. 2017 Feb 06; 17(1):123. PMID: 28166728.
      View in: PubMed
    13. Van der Zalm MM, van Soelen N, Mandalakas AM, Jacobsen M, Detjen AK, Marx FM, Grewal HM, Cotton MF, Walzl G, Hesseling AC. Re: "It May Be Too Early to Try to Prove the Effect of Deworming on Tuberculin Reactivity". Pediatr Infect Dis J. 2017 Feb; 36(2):241-242. PMID: 28079838.
      View in: PubMed
    14. Mandalakas AM, Ngo K, Alonso Ustero P, Golin R, Anabwani F, Mzileni B, Sikhondze W, Stevens R. BUTIMBA: Intensifying the Hunt for Child TB in Swaziland through Household Contact Tracing. PLoS One. 2017; 12(1):e0169769. PMID: 28107473.
      View in: PubMed
    15. DiNardo AR, Detjen A, Ustero P, Ngo K, Bacha J, Mandalakas AM. Culture is an imperfect and heterogeneous reference standard in pediatric tuberculosis. Tuberculosis (Edinb). 2016 Sep 28. PMID: 27727131.
      View in: PubMed
    16. Fox GJ, Schaaf HS, Mandalakas A, Chiappini E, Zumla A, Marais BJ. Preventing the spread of multidrug-resistant tuberculosis and protecting contacts of infectious cases. Clin Microbiol Infect. 2016 Aug 31. PMID: 27592087.
      View in: PubMed
    17. Van der Zalm MM, van Soelen N, Mandalakas AM, Jacobsen M, Detjen AK, Marx FM, Grewal HM, Cotton MF, Walzl G, Hesseling AC. The Effect of Deworming on Tests of Tuberculosis Infection in Children With Recent Tuberculosis Exposure: A Randomized Controlled Trial. Pediatr Infect Dis J. 2016 Jun; 35(6):622-7. PMID: 26933841.
      View in: PubMed
    18. DiNardo AR, Mace EM, Lesteberg K, Cirillo JD, Mandalakas AM, Graviss EA, Orange JS, Makedonas G. Schistosome Soluble Egg Antigen Decreases Mycobacterium tuberculosis-Specific CD4+ T-Cell Effector Function With Concomitant Arrest of Macrophage Phago-Lysosome Maturation. J Infect Dis. 2016 Aug 1; 214(3):479-88. PMID: 27389351; PMCID: PMC4936644 [Available on 08/01/17].
    19. DiNardo AR, Mandalakas AM, Maphalala G, Mtetwa G, Mndzebele T, Ustero P, Hlatshwayo M, Mace EM, Orange JS, Makedonas G. HIV Progression Perturbs the Balance of the Cell-Mediated and Anti-Inflammatory Adaptive and Innate Mycobacterial Immune Response. Mediators Inflamm. 2016; 2016:1478340. PMID: 27006526; PMCID: PMC4781991.
    20. DiNardo AR, Lange C, Mandalakas AM. Editorial Commentary: 1, 2, 3 (Years)??…??and You're Out: The End of a 123-year Historic Era. Clin Infect Dis. 2016 May 1; 62(9):1089-91. PMID: 26839384.
      View in: PubMed
    21. Lange C, Mandalakas AM, Kalsdorf B, Denkinger CM, Sester M. Clinical Application of Interferon-? Release Assays for the Prevention of Tuberculosis in Countries with Low Incidence. Pathog Immun. 2016; 1(2):308-329. PMID: 28217762.
      View in: PubMed
    22. DiNardo AR, Hahn A, Leyden J, Stager C, Baron EJ, Graviss EA, Mandalakas AM, Guy E. Use of string test and stool specimens to diagnose pulmonary tuberculosis. Int J Infect Dis. 2015 Dec; 41:50-2. PMID: 26523638.
      View in: PubMed
    23. Graham SM, Cuevas LE, Jean-Philippe P, Browning R, Casenghi M, Detjen AK, Gnanashanmugam D, Hesseling AC, Kampmann B, Mandalakas A, Marais BJ, Schito M, Spiegel HM, Starke JR, Worrell C, Zar HJ. Clinical Case Definitions for Classification of Intrathoracic Tuberculosis in Children: An Update. Clin Infect Dis. 2015 Oct 15; 61Suppl 3:S179-87. PMID: 26409281.
      View in: PubMed
    24. Priya Dhar C, Elena Gonzalez B, Dragga T, Bothe D, Mandalakas AM. Testing International Adoptees for Tuberculosis. Pediatr Infect Dis J. 2015 Oct; 34(10):1138-9. PMID: 26367807.
      View in: PubMed
    25. Mandalakas AM, Kirchner HL, Walzl G, Gie RP, Schaaf HS, Cotton MF, Grewal HM, Hesseling AC. Optimizing the detection of recent tuberculosis infection in children in a high tuberculosis-HIV burden setting. Am J Respir Crit Care Med. 2015 Apr 1; 191(7):820-30. PMID: 25622087; PMCID: PMC4407483.
    26. Wiseman CA, Mandalakas AM, Kirchner HL, Gie RP, Schaaf HS, Walters E, Hesseling AC. Novel application of NIH case definitions in a paediatric tuberculosis contact investigation study. Int J Tuberc Lung Dis. 2015 Apr; 19(4):446-53. PMID: 25860001.
      View in: PubMed
    27. Detjen AK, DiNardo AR, Leyden J, Steingart KR, Menzies D, Schiller I, Dendukuri N, Mandalakas AM. Xpert MTB/RIF assay for the diagnosis of pulmonary tuberculosis in children: a systematic review and meta-analysis. Lancet Respir Med. 2015 Jun; 3(6):451-61. PMID: 25812968.
      View in: PubMed
    28. Carlucci JG, Jin L, Sanders JE, Mohapi EQ, Mandalakas AM. Development of tuberculosis infection control guidelines in a pediatric HIV clinic in sub-Saharan Africa. Public Health Action. 2015 Mar 21; 5(1):2-5. PMID: 26400595.
      View in: PubMed
    29. Musuuza JS, Singer ME, Mandalakas AM, Katamba A. Key actors' perspectives on cost-effectiveness analysis in Uganda: a cross-sectional survey. BMC Health Serv Res. 2014; 14:539. PMID: 25363234; PMCID: PMC4232642.
    30. Ballif M, Renner L, Claude Dusingize J, Leroy V, Ayaya S, Wools-Kaloustian K, Cortes CP, McGowan CC, Graber C, Mandalakas AM, Mofenson LM, Egger M, Kumara Wati KD, Nallusamy R, Reubenson G, Davies MA, Fenner L. Tuberculosis in Pediatric Antiretroviral Therapy Programs in Low- and Middle-Income Countries: Diagnosis and Screening Practices. J Pediatric Infect Dis Soc. 2015 Mar; 4(1):30-8. PMID: 26407355.
      View in: PubMed
    31. van Soelen N, du Preez K, van Wyk SS, Mandalakas AM, Enarson DA, Reid AJ, Hesseling AC. Does an isoniazid prophylaxis register improve tuberculosis contact management in South African children? PLoS One. 2013; 8(12):e80803. PMID: 24339884; PMCID: PMC3858233.
    32. Skinner D, Hesseling AC, Francis C, Mandalakas AM. It's hard work, but it's worth it: the task of keeping children adherent to isoniazid preventive therapy. Public Health Action. 2013 Sep 21; 3(3):191-8. PMID: 26393028.
      View in: PubMed
    33. Cruz AT, Ahmed A, Mandalakas AM, Starke JR. Treatment of Latent Tuberculosis Infection in Children. J Pediatric Infect Dis Soc. 2013 Sep; 2(3):248-58. PMID: 26619479.
      View in: PubMed
    34. Chegou NN, Detjen AK, Thiart L, Walters E, Mandalakas AM, Hesseling AC, Walzl G. Utility of host markers detected in Quantiferon supernatants for the diagnosis of tuberculosis in children in a high-burden setting. PLoS One. 2013; 8(5):e64226. PMID: 23691173; PMCID: PMC3655018.
    35. Mandalakas AM, van Wyk S, Kirchner HL, Walzl G, Cotton M, Rabie H, Kriel B, Gie RP, Schaaf HS, Hesseling AC. Detecting tuberculosis infection in HIV-infected children: a study of diagnostic accuracy, confounding and interaction. Pediatr Infect Dis J. 2013 Mar; 32(3):e111-8. PMID: 23190784.
      View in: PubMed
    36. Skinner D, Mandalakas AM. Pasting together the preventive therapy puzzle. Int J Tuberc Lung Dis. 2013 Feb; 17(2):175-7. PMID: 23211672.
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    37. Cruz AT, Mandalakas AM, Starke JR. Childhood tuberculosis: a preventable disease not being prevented. Pediatrics. 2012 Dec; 130(6):e1672-3. PMID: 23184112.
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    38. van Soelen N, Mandalakas AM, Kirchner HL, Walzl G, Grewal HM, Jacobsen M, Hesseling AC. Effect of Ascaris Lumbricoides specific IgE on tuberculin skin test responses in children in a high-burden setting: a cross-sectional community-based study. BMC Infect Dis. 2012; 12:211. PMID: 22966931; PMCID: PMC3482567.
    39. Mandalakas AM, Hesseling AC, Gie RP, Schaaf HS, Marais BJ, Sinanovic E. Modelling the cost-effectiveness of strategies to prevent tuberculosis in child contacts in a high-burden setting. Thorax. 2013 Mar; 68(3):247-55. PMID: 22717944.
      View in: PubMed
    40. Mandalakas AM, Kirchner HL, Lombard C, Walzl G, Grewal HM, Gie RP, Hesseling AC. Well-quantified tuberculosis exposure is a reliable surrogate measure of tuberculosis infection. Int J Tuberc Lung Dis. 2012 Aug; 16(8):1033-9. PMID: 22692027.
      View in: PubMed
    41. Cuevas LE, Browning R, Bossuyt P, Casenghi M, Cotton MF, Cruz AT, Dodd LE, Drobniewski F, Gale M, Graham SM, Grzemska M, Heinrich N, Hesseling AC, Huebner R, Jean-Philippe P, Kabra SK, Kampmann B, Lewinsohn D, Li M, Lienhardt C, Mandalakas AM, Marais BJ, Menzies HJ, Montepiedra G, Mwansambo C, Oberhelman R, Palumbo P, Russek-Cohen E, Shapiro DE, Smith B, Soto-Castellares G, Starke JR, Swaminathan S, Wingfield C, Worrell C. Evaluation of tuberculosis diagnostics in children: 2. Methodological issues for conducting and reporting research evaluations of tuberculosis diagnostics for intrathoracic tuberculosis in children. Consensus from an expert panel. J Infect Dis. 2012 May 15; 205 Suppl 2:S209-15. PMID: 22476719; PMCID: PMC3334504.
    42. Van Wyk SS, Mandalakas AM, Enarson DA, Gie RP, Beyers N, Hesseling AC. Tuberculosis contact investigation in a high-burden setting: house or household? Int J Tuberc Lung Dis. 2012 Feb; 16(2):157-62. PMID: 22236914.
      View in: PubMed
    43. Hesseling AC, Mandalakas AM. Interferon-gamma release assays for childhood tuberculosis: what does the future hold? Int J Tuberc Lung Dis. 2011 Nov; 15(11):1423-4. PMID: 22008752.
      View in: PubMed
    44. du Preez K, Mandalakas AM, Kirchner HL, Grewal HM, Schaaf HS, van Wyk SS, Hesseling AC. Environmental tobacco smoke exposure increases Mycobacterium tuberculosis infection risk in children. Int J Tuberc Lung Dis. 2011 Nov; 15(11):1490-6, i. PMID: 22008762.
      View in: PubMed
    45. Mandalakas AM, Detjen AK, Hesseling AC. Can we accurately diagnose tuberculosis infection in children? Pediatr Infect Dis J. 2011 Sep; 30(9):817-8. PMID: 21849864.
      View in: PubMed
    46. Mandalakas AM, Detjen AK, Hesseling AC, Benedetti A, Menzies D. Interferon-gamma release assays and childhood tuberculosis: systematic review and meta-analysis. Int J Tuberc Lung Dis. 2011 Aug; 15(8):1018-32. PMID: 21669030.
      View in: PubMed
    47. van Wyk SS, Reid AJ, Mandalakas AM, Enarson DA, Beyers N, Morrison J, Hesseling AC. Operational challenges in managing Isoniazid Preventive Therapy in child contacts: a high-burden setting perspective. BMC Public Health. 2011; 11:544. PMID: 21740580; PMCID: PMC3150266.
    48. Duncan B, Mandalakas A, Staton D, Anders B, Kurbasic M, Nakakeeto M, Mustafa G, Reyes A, Evangelista D. Child healthcare workers in resource-limited areas improve health with innovative low-cost projects. J Trop Pediatr. 2012 Apr; 58(2):120-4. PMID: 21652575.
      View in: PubMed
    49. Mandalakas AM, Menzies D. Is screening immigrants for latent tuberculosis cost-effective? Lancet Infect Dis. 2011 Jun; 11(6):418-9. PMID: 21616450.
      View in: PubMed
    50. George SA, Ko CA, Kirchner HL, Starke JR, Dragga TA, Mandalakas AM. The role of chest radiographs and tuberculin skin tests in tuberculosis screening of internationally adopted children. Pediatr Infect Dis J. 2011 May; 30(5):387-91. PMID: 21076362.
      View in: PubMed
    51. Park H, Bothe D, Holsinger E, Kirchner HL, Olness K, Mandalakas A. The impact of nutritional status and longitudinal recovery of motor and cognitive milestones in internationally adopted children. Int J Environ Res Public Health. 2011 Jan; 8(1):105-16. PMID: 21318018; PMCID: PMC3037064.
    52. Du Preez K, Hesseling AC, Mandalakas AM, Marais BJ, Schaaf HS. Opportunities for chemoprophylaxis in children with culture-confirmed tuberculosis. Ann Trop Paediatr. 2011; 31(4):301-10. PMID: 22041464.
      View in: PubMed
    53. Hesseling AC, Marais BJ, Kirchner HL, Mandalakas AM, Brittle W, Victor TC, Warren RM, Schaaf HS. Mycobacterial genotype is associated with disease phenotype in children. Int J Tuberc Lung Dis. 2010 Oct; 14(10):1252-8. PMID: 20843415.
      View in: PubMed
    54. Van Wyk SS, Hamade H, Hesseling AC, Beyers N, Enarson DA, Mandalakas AM. Recording isoniazid preventive therapy delivery to children: operational challenges. Int J Tuberc Lung Dis. 2010 May; 14(5):650-3. PMID: 20392361.
      View in: PubMed
    55. Yeo KT, Zhu X, Kirchner HL, LaBeaud AD, Mandalakas A. Candida skin testing is a poor adjunct to tuberculin skin testing in international adoptees. Pediatr Infect Dis J. 2009 Nov; 28(11):1020-1. PMID: 19820428; PMCID: PMC3133951.
    56. Verla-Tebit E, Zhu X, Holsinger E, Mandalakas AM. Predictive value of immunization records and risk factors for immunization failure in internationally adopted children. Arch Pediatr Adolesc Med. 2009 May; 163(5):473-9. PMID: 19414695.
      View in: PubMed
    57. Hesseling AC, Gie RP, Mandalakas AM. The predictive value of the ELISpot-based interferon-gamma-release assay for tuberculosis disease. Ann Intern Med. 2009 Mar 17; 150(6):428-9; author reply 429-30. PMID: 19293083.
      View in: PubMed
    58. Mandalakas AM, Chandawarkar A, Holsinger E. Global child health fellowship programs in demand. Pediatrics. 2008 Dec; 122(6):1417-8; author reply 1418. PMID: 19047273.
      View in: PubMed
    59. Mandalakas AM, Kirchner HL, Zhu X, Yeo KT, Starke JR. Interpretation of repeat tuberculin skin testing in international adoptees: conversions or boosting. Pediatr Infect Dis J. 2008 Oct; 27(10):913-9. PMID: 18776820.
      View in: PubMed
    60. Hesseling AC, Mandalakas AM, Kirchner HL, Chegou NN, Marais BJ, Stanley K, Zhu X, Black G, Beyers N, Walzl G. Highly discordant T cell responses in individuals with recent exposure to household tuberculosis. Thorax. 2009 Oct; 64(10):840-6. PMID: 18682523.
      View in: PubMed
    61. LaBeaud AD, Gorman AM, Koonce J, Kippes C, McLeod J, Lynch J, Gallagher T, King CH, Mandalakas AM. Rapid GIS-based profiling of West Nile virus transmission: defining environmental factors associated with an urban-suburban outbreak in Northeast Ohio, USA. Geospat Health. 2008 May; 2(2):215-25. PMID: 18686270; PMCID: PMC3140769.
    62. Mandalakas AM, Hesseling AC, Chegou NN, Kirchner HL, Zhu X, Marais BJ, Black GF, Beyers N, Walzl G. High level of discordant IGRA results in HIV-infected adults and children. Int J Tuberc Lung Dis. 2008 Apr; 12(4):417-23. PMID: 18371268.
      View in: PubMed
    63. Mandalakas AM, Kirchner HL, Iverson S, Chesney M, Spencer MJ, Sidler A, Johnson D. Predictors of Mycobacterium tuberculosis infection in international adoptees. Pediatrics. 2007 Sep; 120(3):e610-6. PMID: 17766501.
      View in: PubMed
    64. LaBeaud AD, Kile JR, Kippes C, King CH, Mandalakas AM. Exposure to West Nile virus during the 2002 epidemic in Cuyahoga County, Ohio: a comparison of pediatric and adult behaviors. Public Health Rep. 2007 May-Jun; 122(3):356-61. PMID: 17518307; PMCID: PMC1847498.
    65. LaBeaud AD, Lisgaris MV, King CH, Mandalakas AM. Pediatric West Nile virus infection: neurologic disease presentations during the 2002 epidemic in Cuyahoga County, Ohio. Pediatr Infect Dis J. 2006 Aug; 25(8):751-3. PMID: 16874181.
      View in: PubMed
    66. Mandalakas AM, Kippes C, Sedransk J, Kile JR, Garg A, McLeod J, Berry RL, Marfin AA. West Nile virus epidemic, northeast Ohio, 2002. Emerg Infect Dis. 2005 Nov; 11(11):1774-7. PMID: 16318737; PMCID: PMC3367333.
    67. Mandalakas AM, Starke JR. Current concepts of childhood tuberculosis. Semin Pediatr Infect Dis. 2005 Apr; 16(2):93-104. PMID: 15825140.
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    68. Mandalakas AM, Starke JR. Tuberculosis screening in immigrant children. Pediatr Infect Dis J. 2004 Jan; 23(1):71-2. PMID: 14743051.
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    69. Torjesen K, Mandalakas A, Kahn R, Duncan B. International child health electives for pediatric residents. Arch Pediatr Adolesc Med. 1999 Dec; 153(12):1297-302. PMID: 10591310.
      View in: PubMed
    70. Mandalakas AM, Guay L, Musoke P, Carroll-Pankhurst C, Olness KN. Human immunodeficiency virus status and delayed-type hypersensitivity skin testing in Ugandan children. Pediatrics. 1999 Feb; 103(2):E21. PMID: 9925867.
      View in: PubMed
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