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TETSUO ASHIZAWA

TitleAdjunct Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Neurology
DivisionNeurology
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    R01NS041547     (ASHIZAWA, TETSUO)May 1, 2001 - Mar 31, 2010
    NIH/NINDS
    Pathogenic Mechanism of Spinocerebellar Ataxia Type 10
    Role: Principal Investigator

    RC1NS068897     (ASHIZAWA, TETSUO)Sep 30, 2009 - Aug 31, 2012
    NIH/NINDS
    Clinical Research Consortium for Spinocerebellar Ataxias
    Role: Principal Investigator

    R01NS083564     (ASHIZAWA, TETSUO)May 1, 2013 - Jan 31, 2018
    NIH/NINDS
    RNA-Gain-of-Function Pathogenesis in SCA10
    Role: Principal Investigator

    U01NS104326     (ASHIZAWA, TETSUO)Jan 1, 2018 - Dec 31, 2022
    NIH/NINDS
    Clinical Trial Readiness for SCA1 and SCA3
    Role: Principal Investigator

    R13NS111955     (ASHIZAWA, TETSUO)Mar 15, 2019 - Dec 31, 2019
    NIH/NINDS
    The 1st SCA Global Conference
    Role: Principal Investigator

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    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Domingues BMD, Nascimento FA, Meira AT, Moro A, Raskin S, Ashizawa T, Teive HAG. Clinical and Genetic Evaluation of Spinocerebellar Ataxia Type 10 in 16 Brazilian Families. Cerebellum. 2019 Oct; 18(5):849-854. PMID: 31377949.
      View in: PubMed
    2. Nascimento FA, Rodrigues VOR, Pelloso FC, Camargo CHF, Moro A, Raskin S, Ashizawa T, Teive HAG. Spinocerebellar ataxias in Southern Brazil: Genotypic and phenotypic evaluation of 213 families. Clin Neurol Neurosurg. 2019 Sep; 184:105427. PMID: 31323545.
      View in: PubMed
    3. Lai RY, Tomishon D, Figueroa KP, Pulst SM, Perlman S, Wilmot G, Gomez CM, Schmahmann JD, Paulson H, Shakkottai VG, Ying SH, Zesiewicz T, Bushara K, Geschwind M, Xia G, Subramony SH, Ashizawa T, Kuo SH. Tremor in the Degenerative Cerebellum: Towards the Understanding of Brain Circuitry for Tremor. Cerebellum. 2019 Jun; 18(3):519-526. PMID: 30830673.
      View in: PubMed
    4. Gao R, Chakraborty A, Geater C, Pradhan S, Gordon KL, Snowden J, Yuan S, Dickey AS, Choudhary S, Ashizawa T, Ellerby LM, La Spada AR, Thompson LM, Hazra TK, Sarkar PS. Mutant huntingtin impairs PNKP and ATXN3, disrupting DNA repair and transcription. Elife. 2019 Apr 17; 8. PMID: 30994454.
      View in: PubMed
    5. Ashizawa AT, Holt J, Faust K, Liu W, Tiwari A, Zhang N, Ashizawa T. Intravenously Administered Novel Liposomes, DCL64, Deliver Oligonucleotides to Cerebellar Purkinje Cells. Cerebellum. 2019 Feb; 18(1):99-108. PMID: 29987489.
      View in: PubMed
    6. Moscovich M, Munhoz RP, Moro A, Raskin S, McFarland K, Ashizawa T, Teive HAG, Silveira-Moriyama L. Olfactory Function in SCA10. Cerebellum. 2019 Feb; 18(1):85-90. PMID: 29922950.
      View in: PubMed
    7. Ashizawa T, Gagnon C, Groh WJ, Gutmann L, Johnson NE, Meola G, Moxley R, Pandya S, Rogers MT, Simpson E, Angeard N, Bassez G, Berggren KN, Bhakta D, Bozzali M, Broderick A, Byrne JLB, Campbell C, Cup E, Day JW, De Mattia E, Duboc D, Duong T, Eichinger K, Ekstrom AB, van Engelen B, Esparis B, Eymard B, Ferschl M, Gadalla SM, Gallais B, Goodglick T, Heatwole C, Hilbert J, Holland V, Kierkegaard M, Koopman WJ, Lane K, Maas D, Mankodi A, Mathews KD, Monckton DG, Moser D, Nazarian S, Nguyen L, Nopoulos P, Petty R, Phetteplace J, Puymirat J, Raman S, Richer L, Roma E, Sampson J, Sansone V, Schoser B, Sterling L, Statland J, Subramony SH, Tian C, Trujillo C, Tomaselli G, Turner C, Venance S, Verma A, White M, Winblad S. Consensus-based care recommendations for adults with myotonic dystrophy type 1. Neurol Clin Pract. 2018 Dec; 8(6):507-520. PMID: 30588381.
      View in: PubMed
    8. Ashizawa T, Öz G, Paulson HL. Author Correction: Spinocerebellar ataxias: prospects and challenges for therapy development. Nat Rev Neurol. 2018 Dec; 14(12):749. PMID: 30410042.
      View in: PubMed
    9. Ding D, Wang C, Chen Z, Peng H, Li K, Zhou X, Peng Y, Wang P, Hou X, Li T, Qiu R, Xia K, Sequeiros J, Ashizawa T, Tang B, Jiang H. Polymorphisms in DNA methylation-related genes are linked to the phenotype of Machado-Joseph disease. Neurobiol Aging. 2019 03; 75:225.e1-225.e8. PMID: 30554804.
      View in: PubMed
    10. Fabiani G, Martins R, Ashizawa T, Germiniani FMB, Teive HAG. 99mTc-TRODAT-1 SPECT Showing Dopaminergic Deficiency in a Patient with Spinocerebellar Ataxia Type 10 and Parkinsonism. Mov Disord Clin Pract. 2019 Jan; 6(1):85-87. PMID: 30746424.
      View in: PubMed
    11. Xia G, Terada N, Ashizawa T. Human iPSC Models to Study Orphan Diseases: Muscular Dystrophies. Curr Stem Cell Rep. 2018; 4(4):299-309. PMID: 30524939.
      View in: PubMed
    12. Ashizawa T, Öz G, Paulson HL. Spinocerebellar ataxias: prospects and challenges for therapy development. Nat Rev Neurol. 2018 10; 14(10):590-605. PMID: 30131520.
      View in: PubMed
    13. Wang Y, Hao L, Wang H, Santostefano K, Thapa A, Cleary J, Li H, Guo X, Terada N, Ashizawa T, Xia G. Therapeutic Genome Editing for Myotonic Dystrophy Type 1 Using CRISPR/Cas9. Mol Ther. 2018 11 07; 26(11):2617-2630. PMID: 30274788.
      View in: PubMed
    14. Ayhan F, Perez BA, Shorrock HK, Zu T, Banez-Coronel M, Reid T, Furuya H, Clark HB, Troncoso JC, Ross CA, Subramony SH, Ashizawa T, Wang ET, Yachnis AT, Ranum LP. SCA8 RAN polySer protein preferentially accumulates in white matter regions and is regulated by eIF3F. EMBO J. 2018 10 01; 37(19). PMID: 30206144.
      View in: PubMed
    15. Hamedani AG, Hauser LA, Perlman S, Mathews K, Wilmot GR, Zesiewicz T, Subramony SH, Ashizawa T, Delatycki MB, Brocht A, Lynch DR. Longitudinal analysis of contrast acuity in Friedreich ataxia. Neurol Genet. 2018 Aug; 4(4):e250. PMID: 30065952.
      View in: PubMed
    16. Leite CMBA, Schieferdecker MEM, Frehner C, Munhoz RP, Ashizawa T, Teive HAG. Body composition in Spinocerebellar ataxia type 3 and 10 patients: Comparative study with control group. Nutr Neurosci. 2018 May 07; 1-6. PMID: 29734917.
      View in: PubMed
    17. London E, Camargo CHF, Zanatta A, Crippa AC, Raskin S, Munhoz RP, Ashizawa T, Teive HAG. Sleep disorders in spinocerebellar ataxia type 10. J Sleep Res. 2018 10; 27(5):e12688. PMID: 29624773.
      View in: PubMed
    18. Sznajder LJ, Thomas JD, Carrell EM, Reid T, McFarland KN, Cleary JD, Oliveira R, Nutter CA, Bhatt K, Sobczak K, Ashizawa T, Thornton CA, Ranum LPW, Swanson MS. Intron retention induced by microsatellite expansions as a disease biomarker. Proc Natl Acad Sci U S A. 2018 04 17; 115(16):4234-4239. PMID: 29610297.
      View in: PubMed
    19. Silva GV, Bonilha P, Moro A, Munhoz R, Raskin S, Ashizawa T, Nascimento FA, Teive HAG. Spinocerebellar ataxias type 3 and 10: Onset and progression of ataxia during pregnancy and puerperium. Parkinsonism Relat Disord. 2018 07; 52:119-120. PMID: 29609848.
      View in: PubMed
    20. Ashizawa T. A crystal ball for survival for spinocerebellar ataxias? Lancet Neurol. 2018 04; 17(4):292-294. PMID: 29553373.
      View in: PubMed
    21. Zesiewicz TA, Wilmot G, Kuo SH, Perlman S, Greenstein PE, Ying SH, Ashizawa T, Subramony SH, Schmahmann JD, Figueroa KP, Mizusawa H, Schöls L, Shaw JD, Dubinsky RM, Armstrong MJ, Gronseth GS, Sullivan KL. Comprehensive systematic review summary: Treatment of cerebellar motor dysfunction and ataxia: Report of the Guideline Development, Dissemination, and Implementation Subcommittee of the American Academy of Neurology. Neurology. 2018 03 06; 90(10):464-471. PMID: 29440566.
      View in: PubMed
    22. Moro A, Munhoz RP, Moscovich M, Arruda WO, Raskin S, Silveira-Moriyama L, Ashizawa T, Teive HAG. Nonmotor Symptoms in Patients with Spinocerebellar Ataxia Type 10. Cerebellum. 2017 Dec; 16(5-6):938-944. PMID: 28589261.
      View in: PubMed
    23. Zhang L, McFarland KN, Subramony SH, Heilman KM, Ashizawa T. Correction to: SPG7 and Impaired Emotional Communication. Cerebellum. 2017 12; 16(5-6):991. PMID: 29181771.
      View in: PubMed
    24. Figueroa KP, Gan SR, Perlman S, Wilmot G, Gomez CM, Schmahmann J, Paulson H, Shakkottai VG, Ying SH, Zesiewicz T, Bushara K, Geschwind M, Xia G, Subramony SH, Ashizawa T, Pulst SM, Kuo SH. C9orf72 repeat expansions as genetic modifiers for depression in spinocerebellar ataxias. Mov Disord. 2018 03; 33(3):497-498. PMID: 29193335.
      View in: PubMed
    25. Kuo PH, Gan SR, Wang J, Lo RY, Figueroa KP, Tomishon D, Pulst SM, Perlman S, Wilmot G, Gomez CM, Schmahmann JD, Paulson H, Shakkottai VG, Ying SH, Zesiewicz T, Bushara K, Geschwind MD, Xia G, Subramony SH, Ashizawa T, Kuo SH. Dystonia and ataxia progression in spinocerebellar ataxias. Parkinsonism Relat Disord. 2017 Dec; 45:75-80. PMID: 29089256.
      View in: PubMed
    26. Gan SR, Wang J, Figueroa KP, Pulst SM, Tomishon D, Lee D, Perlman S, Wilmot G, Gomez CM, Schmahmann J, Paulson H, Shakkottai VG, Ying SH, Zesiewicz T, Bushara K, Geschwind MD, Xia G, Subramony SH, Ashizawa T, Kuo SH. Postural Tremor and Ataxia Progression in Spinocerebellar Ataxias. Tremor Other Hyperkinet Mov (N Y). 2017; 7:492. PMID: 29057148.
      View in: PubMed
    27. Zu T, Cleary JD, Liu Y, Bañez-Coronel M, Bubenik JL, Ayhan F, Ashizawa T, Xia G, Clark HB, Yachnis AT, Swanson MS, Ranum LPW. RAN Translation Regulated by Muscleblind Proteins in Myotonic Dystrophy Type 2. Neuron. 2017 Sep 13; 95(6):1292-1305.e5. PMID: 28910618.
      View in: PubMed
    28. Spina Tensini F, Sato MT, Shiokawa N, Ashizawa T, Teive HAG. A Comparative Optical Coherence Tomography Study of Spinocerebellar Ataxia Types 3 and 10. Cerebellum. 2017 08; 16(4):797-801. PMID: 28401494.
      View in: PubMed
    29. Luo L, Wang J, Lo RY, Figueroa KP, Pulst SM, Kuo PH, Perlman S, Wilmot G, Gomez CM, Schmahmann J, Paulson H, Shakkottai VG, Ying SH, Zesiewicz T, Bushara K, Geschwind M, Xia G, Subramony SH, Ashizawa T, Kuo SH. The Initial Symptom and Motor Progression in Spinocerebellar Ataxias. Cerebellum. 2017 06; 16(3):615-622. PMID: 27848087.
      View in: PubMed
    30. Landrian I, McFarland KN, Liu J, Mulligan CJ, Rasmussen A, Ashizawa T. Inheritance patterns of ATCCT repeat interruptions in spinocerebellar ataxia type 10 (SCA10) expansions. PLoS One. 2017; 12(4):e0175958. PMID: 28423040.
      View in: PubMed
    31. Chen Z, Wang C, Zheng C, Long Z, Cao L, Li X, Shang H, Yin X, Zhang B, Liu J, Ding D, Peng Y, Peng H, Ye W, Qiu R, Pan Q, Xia K, Chen S, Sequeiros J, Ashizawa T, Tang B, Jiang H. Ubiquitin-related network underlain by (CAG)n loci modulate age at onset in Machado-Joseph disease. Brain. 2017 04 01; 140(4):e25. PMID: 28334945.
      View in: PubMed
    32. Zhang L, McFarland KN, Subramony SH, Heilman KM, Ashizawa T. SPG7 and Impaired Emotional Communication. Cerebellum. 2017 04; 16(2):595-598. PMID: 27557734.
      View in: PubMed
    33. Zhang N, Ashizawa T. RNA toxicity and foci formation in microsatellite expansion diseases. Curr Opin Genet Dev. 2017 Jun; 44:17-29. PMID: 28208060.
      View in: PubMed
    34. Li PP, Sun X, Xia G, Arbez N, Paul S, Zhu S, Peng HB, Ross CA, Koeppen AH, Margolis RL, Pulst SM, Ashizawa T, Rudnicki DD. ATXN2-AS, a gene antisense to ATXN2, is associated with spinocerebellar ataxia type 2 and amyotrophic lateral sclerosis. Ann Neurol. 2016 10; 80(4):600-15. PMID: 27531668.
      View in: PubMed
    35. Ashizawa T, Xia G. Ataxia. Continuum (Minneap Minn). 2016 Aug; 22(4 Movement Disorders):1208-26. PMID: 27495205.
      View in: PubMed
    36. Kang N, Christou EA, Burciu RG, Chung JW, DeSimone JC, Ofori E, Ashizawa T, Subramony SH, Vaillancourt DE. Sensory and motor cortex function contributes to symptom severity in spinocerebellar ataxia type 6. Brain Struct Funct. 2017 03; 222(2):1039-1052. PMID: 27352359.
      View in: PubMed
    37. Gao Y, Guo X, Santostefano K, Wang Y, Reid T, Zeng D, Terada N, Ashizawa T, Xia G. Genome Therapy of Myotonic Dystrophy Type 1 iPS Cells for Development of Autologous Stem Cell Therapy. Mol Ther. 2016 08; 24(8):1378-87. PMID: 27203440.
      View in: PubMed
    38. Chen Z, Zheng C, Long Z, Cao L, Li X, Shang H, Yin X, Zhang B, Liu J, Ding D, Peng Y, Wang C, Peng H, Ye W, Qiu R, Pan Q, Xia K, Chen S, Sequeiros J, Ashizawa T, Klockgether T, Tang B, Jiang H. (CAG)n loci as genetic modifiers of age-at-onset in patients with Machado-Joseph disease from mainland China. Brain. 2016 08; 139(Pt 8):e41. PMID: 27085188.
      View in: PubMed
    39. Jen JC, Ashizawa T, Griggs RC, Waters MF. Rare neurological channelopathies--networks to study patients, pathogenesis and treatment. Nat Rev Neurol. 2016 Apr; 12(4):195-203. PMID: 26943780.
      View in: PubMed
    40. Paap BK, Roeske S, Durr A, Schöls L, Ashizawa T, Boesch S, Bunn LM, Delatycki MB, Giunti P, Lehéricy S, Mariotti C, Melegh J, Pandolfo M, Tallaksen CME, Timmann D, Tsuji S, Schulz JB, van de Warrenburg BP, Klockgether T. Standardized Assessment of Hereditary Ataxia Patients in Clinical Studies. Mov Disord Clin Pract. 2016 May-Jun; 3(3):230-240. PMID: 30363623.
      View in: PubMed
    41. Aranca TV, Jones TM, Shaw JD, Staffetti JS, Ashizawa T, Kuo SH, Fogel BL, Wilmot GR, Perlman SL, Onyike CU, Ying SH, Zesiewicz TA. Emerging therapies in Friedreich's ataxia. Neurodegener Dis Manag. 2016; 6(1):49-65. PMID: 26782317.
      View in: PubMed
    42. Shi Y, Wang C, Huang F, Chen Z, Sun Z, Wang J, Tang B, Ashizawa T, Klockgether T, Jiang H. High Serum GFAP Levels in SCA3/MJD May Not Correlate with Disease Progression. Cerebellum. 2015 Dec; 14(6):677-81. PMID: 25869927.
      View in: PubMed
    43. Lo RY, Figueroa KP, Pulst SM, Perlman S, Wilmot G, Gomez C, Schmahmann J, Paulson H, Shakkottai VG, Ying S, Zesiewicz T, Bushara K, Geschwind M, Xia G, Yu JT, Lee LE, Ashizawa T, Subramony SH, Kuo SH. Depression and clinical progression in spinocerebellar ataxias. Parkinsonism Relat Disord. 2016 Jan; 22:87-92. PMID: 26644294.
      View in: PubMed
    44. Wang K, McFarland KN, Liu J, Zeng D, Landrian I, Xia G, Hao Y, Jin M, Mulligan CJ, Gu W, Ashizawa T. Spinocerebellar ataxia type 10 in Chinese Han. Neurol Genet. 2015 Oct; 1(3):e26. PMID: 27066563.
      View in: PubMed
    45. McFarland KN, Liu J, Landrian I, Godiska R, Shanker S, Yu F, Farmerie WG, Ashizawa T. SMRT Sequencing of Long Tandem Nucleotide Repeats in SCA10 Reveals Unique Insight of Repeat Expansion Structure. PLoS One. 2015; 10(8):e0135906. PMID: 26295943.
      View in: PubMed
    46. Teive HA, Moro A, Moscovich M, Arruda WO, Munhoz RP, Raskin S, Teive GM, Dallabrida N, Ashizawa T. Spinocerebellar ataxia type 10 in the South of Brazil: the Amerindian-Belgian connection. Arq Neuropsiquiatr. 2015 Aug; 73(8):725-7. PMID: 26222367.
      View in: PubMed
    47. Teive HA, Ashizawa T. Primary and secondary ataxias. Curr Opin Neurol. 2015 Aug; 28(4):413-22. PMID: 26132530.
      View in: PubMed
    48. Wang C, Chen Z, Yang F, Jiao B, Peng H, Shi Y, Wang Y, Huang F, Wang J, Shen L, Xia K, Tang B, Ashizawa T, Jiang H. Analysis of the GGGGCC Repeat Expansions of the C9orf72 Gene in SCA3/MJD Patients from China. PLoS One. 2015; 10(6):e0130336. PMID: 26083476.
      View in: PubMed
    49. Xia G, Gao Y, Jin S, Subramony SH, Terada N, Ranum LP, Swanson MS, Ashizawa T. Genome modification leads to phenotype reversal in human myotonic dystrophy type 1 induced pluripotent stem cell-derived neural stem cells. Stem Cells. 2015 Jun; 33(6):1829-38. PMID: 25702800.
      View in: PubMed
    50. Teive HA, Moro A, Moscovich M, Arruda WO, Munhoz RP, Raskin S, Ashizawa T. Ataxia-telangiectasia - A historical review and a proposal for a new designation: ATM syndrome. J Neurol Sci. 2015 Aug 15; 355(1-2):3-6. PMID: 26050521.
      View in: PubMed
    51. Moscovich M, Okun MS, Favilla C, Figueroa KP, Pulst SM, Perlman S, Wilmot G, Gomez C, Schmahmann J, Paulson H, Shakkottai V, Ying S, Zesiewicz T, Kuo SH, Mazzoni P, Bushara K, Xia G, Ashizawa T, Subramony SH. Clinical evaluation of eye movements in spinocerebellar ataxias: a prospective multicenter study. J Neuroophthalmol. 2015 Mar; 35(1):16-21. PMID: 25259863.
      View in: PubMed
    52. Xia G, Ashizawa T. Dynamic changes of nuclear RNA foci in proliferating DM1 cells. Histochem Cell Biol. 2015 Jun; 143(6):557-64. PMID: 25715678.
      View in: PubMed
    53. Long Z, Chen Z, Wang C, Huang F, Peng H, Hou X, Ding D, Ye W, Wang J, Pan Q, Li J, Xia K, Tang B, Ashizawa T, Jiang H. Two novel SNPs in ATXN3 3' UTR may decrease age at onset of SCA3/MJD in Chinese patients. PLoS One. 2015; 10(2):e0117488. PMID: 25689313.
      View in: PubMed
    54. Lo RY, Figueroa KP, Pulst SM, Lin CY, Perlman S, Wilmot G, Gomez CM, Schmahmann J, Paulson H, Shakkottai VG, Ying SH, Zesiewicz T, Bushara K, Geschwind M, Xia G, Subramony SH, Ashizawa T, Kuo SH. Vascular risk factors and clinical progression in spinocerebellar ataxias. Tremor Other Hyperkinet Mov (N Y). 2015; 5:287. PMID: 25713748.
      View in: PubMed
    55. Akbar U, Ashizawa T. Ataxia. Neurol Clin. 2015 Feb; 33(1):225-48. PMID: 25432731.
      View in: PubMed
    56. Chatterjee A, Saha S, Chakraborty A, Silva-Fernandes A, Mandal SM, Neves-Carvalho A, Liu Y, Pandita RK, Hegde ML, Hegde PM, Boldogh I, Ashizawa T, Koeppen AH, Pandita TK, Maciel P, Sarkar PS, Hazra TK. The role of the mammalian DNA end-processing enzyme polynucleotide kinase 3'-phosphatase in spinocerebellar ataxia type 3 pathogenesis. PLoS Genet. 2015 Jan; 11(1):e1004749. PMID: 25633985.
      View in: PubMed
    57. Baizabal-Carvallo JF, Xia G, Botros P, Laguna J, Ashizawa T, Jankovic J. Bolivian kindred with combined spinocerebellar ataxia types 2 and 10. Acta Neurol Scand. 2015 Aug; 132(2):139-42. PMID: 25630585.
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    58. Gao R, Liu Y, Silva-Fernandes A, Fang X, Paulucci-Holthauzen A, Chatterjee A, Zhang HL, Matsuura T, Choudhary S, Ashizawa T, Koeppen AH, Maciel P, Hazra TK, Sarkar PS. Inactivation of PNKP by mutant ATXN3 triggers apoptosis by activating the DNA damage-response pathway in SCA3. PLoS Genet. 2015 Jan; 11(1):e1004834. PMID: 25590633.
      View in: PubMed
    59. Lo RY, Figueroa KP, Pulst SM, Lin CY, Perlman S, Wilmot G, Gomez C, Schmahmann J, Paulson H, Shakkottai VG, Ying S, Zesiewicz T, Bushara K, Geschwind M, Xia G, Subramony SH, Ashizawa T, Kuo SH. Coenzyme Q10 and spinocerebellar ataxias. Mov Disord. 2015 Feb; 30(2):214-20. PMID: 25449974.
      View in: PubMed
    60. Oyama G, Thompson A, Foote KD, Limotai N, Abd-El-Barr M, Maling N, Malaty IA, Rodriguez RL, Subramony SH, Ashizawa T, Okun MS. Deep brain stimulation for tremor associated with underlying ataxia syndromes: a case series and discussion of issues. Tremor Other Hyperkinet Mov (N Y). 2014; 4:228. PMID: 25120941.
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    61. Tezenas du Montcel S, Durr A, Bauer P, Figueroa KP, Ichikawa Y, Brussino A, Forlani S, Rakowicz M, Schöls L, Mariotti C, van de Warrenburg BP, Orsi L, Giunti P, Filla A, Szymanski S, Klockgether T, Berciano J, Pandolfo M, Boesch S, Melegh B, Timmann D, Mandich P, Camuzat A, Goto J, Ashizawa T, Cazeneuve C, Tsuji S, Pulst SM, Brusco A, Riess O, Brice A, Stevanin G. Modulation of the age at onset in spinocerebellar ataxia by CAG tracts in various genes. Brain. 2014 Sep; 137(Pt 9):2444-55. PMID: 24972706.
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    62. Leonardi L, Marcotulli C, McFarland KN, Tessa A, DiFabio R, Santorelli FM, Pierelli F, Ashizawa T, Casali C. Spinocerebellar ataxia type 10 in Peru: the missing link in the Amerindian origin of the disease. J Neurol. 2014 Sep; 261(9):1691-4. PMID: 24935856.
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    63. Matilla-Dueñas A, Ashizawa T, Brice A, Magri S, McFarland KN, Pandolfo M, Pulst SM, Riess O, Rubinsztein DC, Schmidt J, Schmidt T, Scoles DR, Stevanin G, Taroni F, Underwood BR, Sánchez I. Consensus paper: pathological mechanisms underlying neurodegeneration in spinocerebellar ataxias. Cerebellum. 2014 Apr; 13(2):269-302. PMID: 24307138.
      View in: PubMed
    64. McFarland KN, Liu J, Landrian I, Zeng D, Raskin S, Moscovich M, Gatto EM, Ochoa A, Teive HA, Rasmussen A, Ashizawa T. Repeat interruptions in spinocerebellar ataxia type 10 expansions are strongly associated with epileptic seizures. Neurogenetics. 2014 Mar; 15(1):59-64. PMID: 24318420.
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    65. Subramony SH, Advincula J, Perlman S, Rosales RL, Lee LV, Ashizawa T, Waters MF. Comprehensive phenotype of the p.Arg420his allelic form of spinocerebellar ataxia type 13. Cerebellum. 2013 Dec; 12(6):932-6. PMID: 23912307.
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    66. Bushara K, Bower M, Liu J, McFarland KN, Landrian I, Hutter D, Teive HA, Rasmussen A, Mulligan CJ, Ashizawa T. Expansion of the Spinocerebellar ataxia type 10 (SCA10) repeat in a patient with Sioux Native American ancestry. PLoS One. 2013; 8(11):e81342. PMID: 24278426.
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    67. Bachinski LL, Baggerly KA, Neubauer VL, Nixon TJ, Raheem O, Sirito M, Unruh AK, Zhang J, Nagarajan L, Timchenko LT, Bassez G, Eymard B, Gamez J, Ashizawa T, Mendell JR, Udd B, Krahe R. Most expression and splicing changes in myotonic dystrophy type 1 and type 2 skeletal muscle are shared with other muscular dystrophies. Neuromuscul Disord. 2014 Mar; 24(3):227-40. PMID: 24332166.
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    68. Ashizawa T, Figueroa KP, Perlman SL, Gomez CM, Wilmot GR, Schmahmann JD, Ying SH, Zesiewicz TA, Paulson HL, Shakkottai VG, Bushara KO, Kuo SH, Geschwind MD, Xia G, Mazzoni P, Krischer JP, Cuthbertson D, Holbert AR, Ferguson JH, Pulst SM, Subramony SH. Clinical characteristics of patients with spinocerebellar ataxias 1, 2, 3 and 6 in the US; a prospective observational study. Orphanet J Rare Dis. 2013 Nov 13; 8:177. PMID: 24225362.
      View in: PubMed
    69. Teive HA, Ashizawa T. Spinocerebellar ataxia type 10: from Amerindians to Latin Americans. Curr Neurol Neurosci Rep. 2013 Nov; 13(11):393. PMID: 24027006.
      View in: PubMed
    70. Middlebrooks JC, Nick HS, Subramony SH, Advincula J, Rosales RL, Lee LV, Ashizawa T, Waters MF. Mutation in the kv3.3 voltage-gated potassium channel causing spinocerebellar ataxia 13 disrupts sound-localization mechanisms. PLoS One. 2013; 8(10):e76749. PMID: 24116147.
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    71. Xia G, McFarland KN, Wang K, Sarkar PS, Yachnis AT, Ashizawa T. Purkinje cell loss is the major brain pathology of spinocerebellar ataxia type 10. J Neurol Neurosurg Psychiatry. 2013 Dec; 84(12):1409-11. PMID: 23813740.
      View in: PubMed
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    145. Mankodi A, Ashizawa T. Echo of silence: silent mutations, RNA splicing, and neuromuscular diseases. Neurology. 2003 Nov 25; 61(10):1330-1. PMID: 14638949.
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    146. Ashizawa T. [Recent changes in the neurology residency program in the United States]. Rinsho Shinkeigaku. 2003 Nov; 43(11):854-6. PMID: 15152484.
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    147. Walker RH, Rasmussen A, Rudnicki D, Holmes SE, Alonso E, Matsuura T, Ashizawa T, Davidoff-Feldman B, Margolis RL. Huntington's disease--like 2 can present as chorea-acanthocytosis. Neurology. 2003 Oct 14; 61(7):1002-4. PMID: 14557581.
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    148. Higgins JJ, Jankovic J, Lombardi RQ, Pucilowska J, Tan EK, Ashizawa T, Ruszczyk MU. Haplotype analysis of the ETM2 locus in familial essential tremor. Neurogenetics. 2003 Aug; 4(4):185-9. PMID: 12761658.
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    149. Rosa AL, Jankovic J, Ashizawa T. Screening for mutations in the MECP2 (Rett syndrome) gene in Gilles de la Tourette syndrome. Arch Neurol. 2003 Apr; 60(4):502-3. PMID: 12707062.
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    150. Potaman VN, Bissler JJ, Hashem VI, Oussatcheva EA, Lu L, Shlyakhtenko LS, Lyubchenko YL, Matsuura T, Ashizawa T, Leffak M, Benham CJ, Sinden RR. Unpaired structures in SCA10 (ATTCT)n.(AGAAT)n repeats. J Mol Biol. 2003 Feb 28; 326(4):1095-111. PMID: 12589756.
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    151. Lin X, Ashizawa T. SCA10 and ATTCT repeat expansion: clinical features and molecular aspects. Cytogenet Genome Res. 2003; 100(1-4):184-8. PMID: 14526179.
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    152. Abbruzzese C, Costanzi Porrini S, Mariani B, Gould FK, McAbney JP, Monckton DG, Ashizawa T, Giacanelli M. Instability of a premutation allele in homozygous patients with myotonic dystrophy type 1. Ann Neurol. 2002 Oct; 52(4):435-41. PMID: 12325072.
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    153. Sharma R, Bhatti S, Gomez M, Clark RM, Murray C, Ashizawa T, Bidichandani SI. The GAA triplet-repeat sequence in Friedreich ataxia shows a high level of somatic instability in vivo, with a significant predilection for large contractions. Hum Mol Genet. 2002 Sep 01; 11(18):2175-87. PMID: 12189170.
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    154. Rosa AL, Ashizawa T. Genetic ataxia. Neurol Clin. 2002 Aug; 20(3):727-57, vii. PMID: 12432828.
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    155. Grewal RP, Achari M, Matsuura T, Durazo A, Tayag E, Zu L, Pulst SM, Ashizawa T. Clinical features and ATTCT repeat expansion in spinocerebellar ataxia type 10. Arch Neurol. 2002 Aug; 59(8):1285-90. PMID: 12164725.
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    156. Oshima M, Deitiker P, Ashizawa T, Atassi MZ. Vaccination with a MHC class II peptide attenuates cellular and humoral responses against tAChR and suppresses clinical EAMG. Autoimmunity. 2002 May; 35(3):183-90. PMID: 12389643.
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    157. Matsuura T, Ranum LP, Volpini V, Pandolfo M, Sasaki H, Tashiro K, Watase K, Zoghbi HY, Ashizawa T. Spinocerebellar ataxia type 10 is rare in populations other than Mexicans. Neurology. 2002 Mar 26; 58(6):983-4. PMID: 11914424.
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    158. Xu PY, Liang R, Jankovic J, Hunter C, Zeng YX, Ashizawa T, Lai D, Le WD. Association of homozygous 7048G7049 variant in the intron six of Nurr1 gene with Parkinson's disease. Neurology. 2002 Mar 26; 58(6):881-4. PMID: 11914402.
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    159. Fujigasaki H, Tardieu S, Camuzat A, Stevanin G, LeGuern E, Matsuura T, Ashizawa T, Dürr A, Brice A. Spinocerebellar ataxia type 10 in the French population. Ann Neurol. 2002 Mar; 51(3):408-9. PMID: 11891842.
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    160. Matsuura T, Ashizawa T. Polymerase chain reaction amplification of expanded ATTCT repeat in spinocerebellar ataxia type 10. Ann Neurol. 2002 Feb; 51(2):271-2. PMID: 11835387.
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    161. Nagamitsu S, Ashizawa T. Myotonic dystrophies. Adv Neurol. 2002; 88:293-314. PMID: 11908232.
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    162. Matsuura T, Ashizawa T. Spinocerebellar ataxia type 10: a disease caused by a large ATTCT repeat expansion. Adv Exp Med Biol. 2002; 516:79-97. PMID: 12611436.
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    163. Swoboda KJ, Soong BW, McKenna C, Brunt ER, Litt M, Bale JF, Ashizawa T, Bennett LB, Bowcock AM, Roach ES, Gerson D, Matsuura T, Heydemann PT, Nespeca MP, Jankovic J, Leppert M, Ptácek LJ. Paroxysmal kinesigenic dyskinesia and infantile convulsions. Clinical and linkage studies. 2000. Neurology. 2001 Dec; 57(11 Suppl 4):S42-8. PMID: 11775608.
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    164. Ashizawa T, Matsuura T. [Spinocerebellar ataxia type 10 (SCA10): a disease caused by a novel pentanucleotide repeat expansion]. Rinsho Shinkeigaku. 2001 Dec; 41(12):1120-2. PMID: 12235814.
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    165. Rasmussen A, Matsuura T, Ruano L, Yescas P, Ochoa A, Ashizawa T, Alonso E. Clinical and genetic analysis of four Mexican families with spinocerebellar ataxia type 10. Ann Neurol. 2001 Aug; 50(2):234-9. PMID: 11506407.
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    166. Ashizawa T, Subramony SH. What is Kearns-Sayre syndrome after all? Arch Neurol. 2001 Jul; 58(7):1053-4. PMID: 11448292.
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    167. Tan EK, Nagamitsu S, Matsuura T, Khajavi M, Jankovic J, Ondo W, Ashizawa T. Alcohol dehydrogenase polymorphism and Parkinson's disease. Neurosci Lett. 2001 Jun 01; 305(1):70-2. PMID: 11356310.
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    168. Khajavi M, Tari AM, Patel NB, Tsuji K, Siwak DR, Meistrich ML, Terry NH, Ashizawa T. "Mitotic drive" of expanded CTG repeats in myotonic dystrophy type 1 (DM1). Hum Mol Genet. 2001 Apr 01; 10(8):855-63. PMID: 11285251.
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    169. Tan EK, Ashizawa T. Genetic testing in spinocerebellar ataxias: defining a clinical role. Arch Neurol. 2001 Feb; 58(2):191-5. PMID: 11176956.
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    170. Timchenko NA, Cai ZJ, Welm AL, Reddy S, Ashizawa T, Timchenko LT. RNA CUG repeats sequester CUGBP1 and alter protein levels and activity of CUGBP1. J Biol Chem. 2001 Mar 16; 276(11):7820-6. PMID: 11124939.
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    171. Nagamitsu S, Matsuura T, Khajavi M, Armstrong R, Gooch C, Harati Y, Ashizawa T. A "dystrophic" variant of autosomal recessive myotonia congenita caused by novel mutations in the CLCN1 gene. Neurology. 2000 Dec 12; 55(11):1697-703. PMID: 11113225.
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    172. Matsuura T, Yamagata T, Burgess DL, Rasmussen A, Grewal RP, Watase K, Khajavi M, McCall AE, Davis CF, Zu L, Achari M, Pulst SM, Alonso E, Noebels JL, Nelson DL, Zoghbi HY, Ashizawa T. Large expansion of the ATTCT pentanucleotide repeat in spinocerebellar ataxia type 10. Nat Genet. 2000 Oct; 26(2):191-4. PMID: 11017075.
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    173. Tan EK, Khajavi M, Thornby JI, Nagamitsu S, Jankovic J, Ashizawa T. Variability and validity of polymorphism association studies in Parkinson's disease. Neurology. 2000 Aug 22; 55(4):533-8. PMID: 10953187.
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    174. Swoboda KJ, Soong B, McKenna C, Brunt ER, Litt M, Bale JF, Ashizawa T, Bennett LB, Bowcock AM, Roach ES, Gerson D, Matsuura T, Heydemann PT, Nespeca MP, Jankovic J, Leppert M, Ptácek LJ. Paroxysmal kinesigenic dyskinesia and infantile convulsions: clinical and linkage studies. Neurology. 2000 Jul 25; 55(2):224-30. PMID: 10908896.
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    175. Nakayashiki N, Oshima M, Deitiker PR, Ashizawa T, Atassi MZ. Suppression of experimental myasthenia gravis by monoclonal antibodies against MHC peptide region involved in presentation of a pathogenic T-cell epitope. J Neuroimmunol. 2000 Jun 26; 105(2):131-44. PMID: 10742555.
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    176. Petronis A, Vincent JB, Surh LC, Ashizawa T, Kennedy JL. Polyglutamine-containing proteins in schizophrenia: an effect of lymphoblastoid cells? Mol Psychiatry. 2000 May; 5(3):234-6. PMID: 10889522.
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    177. Tan EK, Matsuura T, Nagamitsu S, Khajavi M, Jankovic J, Ashizawa T. Polymorphism of NACP-Rep1 in Parkinson's disease: an etiologic link with essential tremor? Neurology. 2000 Mar 14; 54(5):1195-8. PMID: 10720300.
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    178. Deitiker P, Ashizawa T, Atassi MZ. Antigen mimicry in autoimmune disease. Can immune responses to microbial antigens that mimic acetylcholine receptor act as initial triggers of Myasthenia gravis? Hum Immunol. 2000 Mar; 61(3):255-65. PMID: 10689115.
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    179. Costanzi-Porrini S, Tessarolo D, Abbruzzese C, Liguori M, Ashizawa T, Giacanelli M. An interrupted 34-CAG repeat SCA-2 allele in patients with sporadic spinocerebellar ataxia. Neurology. 2000 Jan 25; 54(2):491-3. PMID: 10668721.
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    180. Burgess DL, Matsuura T, Ashizawa T, Noebels JL. Genetic localization of the Ca2+ channel gene CACNG2 near SCA10 on chromosome 22q13. Epilepsia. 2000 Jan; 41(1):24-7. PMID: 10643919.
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    181. Monckton DG, Cayuela ML, Gould FK, Brock GJ, Silva R, Ashizawa T. Very large (CAG)(n) DNA repeat expansions in the sperm of two spinocerebellar ataxia type 7 males. Hum Mol Genet. 1999 Dec; 8(13):2473-8. PMID: 10556295.
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    182. Linfante I, Ashizawa T. Proton magnetic resonance spectroscopy: an in vivo window to study neurodegenerative disorders. Arch Neurol. 1999 Dec; 56(12):1446-7. PMID: 10593297.
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    183. Bidichandani SI, Purandare SM, Taylor EE, Gumin G, Machkhas H, Harati Y, Gibbs RA, Ashizawa T, Patel PI. Somatic sequence variation at the Friedreich ataxia locus includes complete contraction of the expanded GAA triplet repeat, significant length variation in serially passaged lymphoblasts and enhanced mutagenesis in the flanking sequence. Hum Mol Genet. 1999 Dec; 8(13):2425-36. PMID: 10556290.
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    184. Ashizawa T, Conneally PM. Repeats may not be everything in anticipation. Neurology. 1999 Oct 12; 53(6):1164-5. PMID: 10522865.
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    185. Imai Y, Morishita S, Ikeda Y, Toyoda M, Ashizawa T, Yamamoto K, Inoue T, Ishikawa T. Immunohistochemical and molecular analysis of giant cell carcinoma of the pancreas: a report of three cases. Pancreas. 1999 Apr; 18(3):308-15. PMID: 10206490.
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    186. Matsuura T, Achari M, Khajavi M, Bachinski LL, Zoghbi HY, Ashizawa T. Mapping of the gene for a novel spinocerebellar ataxia with pure cerebellar signs and epilepsy. Ann Neurol. 1999 Mar; 45(3):407-11. PMID: 10072060.
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    187. Thornton CA, Ashizawa T. Getting a grip on the myotonic dystrophies. Neurology. 1999 Jan 01; 52(1):12-3. PMID: 9921841.
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    188. Hisatomi N, Ito K, Nagashima Y, Fujiwara K, Yasuda K, Ashizawa T, Sato M, Higuchi S. [Nurses' knowledge of alcohol-related problems and their treatment: a comparison of nurses in general hospital and alcoholism treatment units]. Nihon Arukoru Yakubutsu Igakkai Zasshi. 1998 Dec; 33(6):671-82. PMID: 10028825.
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    189. Wang WW, Khajavi M, Patel BJ, Beach J, Jankovic J, Ashizawa T. The G209A mutation in the alpha-synuclein gene is not detected in familial cases of Parkinson disease in non-Greek and/or Italian populations. Arch Neurol. 1998 Dec; 55(12):1521-3. PMID: 9865795.
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    190. Benton CS, de Silva R, Rutledge SL, Bohlega S, Ashizawa T, Zoghbi HY. Molecular and clinical studies in SCA-7 define a broad clinical spectrum and the infantile phenotype. Neurology. 1998 Oct; 51(4):1081-6. PMID: 9781533.
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    191. de Silva RN, Stockton DW, Keats B, Justice CM, Richards CS, Ashizawa T. Delayed diagnosis of Friedreich's ataxia due to coexisting recessive deaf/blind syndrome. Neurology. 1998 Jun; 50(6):1924-5. PMID: 9633771.
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    192. Ashizawa T, Shimizu M, Gomi K, Okabe M. Antitumor activity of KW-2170, a novel pyrazoloacridone derivative. Anticancer Drugs. 1998 Mar; 9(3):263-71. PMID: 9625437.
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    193. Ashizawa T. Myotonic dystrophy as a brain disorder. Arch Neurol. 1998 Mar; 55(3):291-3. PMID: 9520000.
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    194. Chance PF, Ashizawa T, Hoffman EP, Crawford TO. Molecular basis of neuromuscular diseases. Phys Med Rehabil Clin N Am. 1998 Feb; 9(1):49-81, vi. PMID: 9894134.
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    195. Bidichandani SI, Ashizawa T, Patel PI. The GAA triplet-repeat expansion in Friedreich ataxia interferes with transcription and may be associated with an unusual DNA structure. Am J Hum Genet. 1998 Jan; 62(1):111-21. PMID: 9443873.
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    196. Ashizawa T. [Instability of myotonic dystrophy CTG trinucleotide repeat]. Rinsho Shinkeigaku. 1997 Dec; 37(12):1151. PMID: 9577674.
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    197. Wong LJ, Ashizawa T. Instability of the (CTG)n repeat in congenital myotonic dystrophy. Am J Hum Genet. 1997 Dec; 61(6):1445-8. PMID: 9399912.
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    198. Bidichandani SI, Ashizawa T, Patel PI. Atypical Friedreich ataxia caused by compound heterozygosity for a novel missense mutation and the GAA triplet-repeat expansion. Am J Hum Genet. 1997 May; 60(5):1251-6. PMID: 9150176.
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    199. Zhuchenko O, Bailey J, Bonnen P, Ashizawa T, Stockton DW, Amos C, Dobyns WB, Subramony SH, Zoghbi HY, Lee CC. Autosomal dominant cerebellar ataxia (SCA6) associated with small polyglutamine expansions in the alpha 1A-voltage-dependent calcium channel. Nat Genet. 1997 Jan; 15(1):62-9. PMID: 8988170.
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    200. Alford RL, Ashizawa T, Jankovic J, Caskey CT, Richards CS. Molecular detection of new mutations, resolution of ambiguous results and complex genetic counseling issues in Huntington disease. Am J Med Genet. 1996 Dec 18; 66(3):281-6. PMID: 8985488.
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    201. Abbruzzese C, Krahe R, Liguori M, Tessarolo D, Siciliano MJ, Ashizawa T, Giacanelli M. Myotonic dystrophy phenotype without expansion of (CTG)n repeat: an entity distinct from proximal myotonic myopathy (PROMM)? J Neurol. 1996 Oct; 243(10):715-21. PMID: 8923304.
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    202. Ashizawa T, Monckton DG, Vaishnav S, Patel BJ, Voskova A, Caskey CT. Instability of the expanded (CTG)n repeats in the myotonin protein kinase gene in cultured lymphoblastoid cell lines from patients with myotonic dystrophy. Genomics. 1996 Aug 15; 36(1):47-53. PMID: 8812415.
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    203. Ashizawa T, Jankovic J. Cervical dystonia as the initial presentation of Huntington's disease. Mov Disord. 1996 Jul; 11(4):457-9. PMID: 8813235.
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    204. Ashizawa T, Saito T, Takahata N. Effects of ceruletide on perioral movements and the dopamine receptor-adenylate cyclase system in rats chronically treated with fluphenazine. Psychopharmacology (Berl). 1996 Jun; 125(3):185-94. PMID: 8815952.
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    205. Petronis A, Heng HH, Tatuch Y, Shi XM, Klempan TA, Tsui LC, Ashizawa T, Surh LC, Holden JJ, Kennedy JL. Direct detection of expanded trinucleotide repeats using PCR and DNA hybridization techniques. Am J Med Genet. 1996 Feb 16; 67(1):85-91. PMID: 8678121.
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    206. Ashizawa T, Okamoto A, Okabe M, Kobayashi S, Arai H, Saito H, Kasai M, Gomi K. Characteristics of the antitumor activity of M-16 and M-18, major metabolites of a new mitomycin C derivative KW-2149, in mice. Anticancer Drugs. 1995 Dec; 6(6):763-70. PMID: 8845489.
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    207. Tokgozoglu LS, Ashizawa T, Pacifico A, Armstrong RM, Epstein HF, Zoghbi WA. Cardiac involvement in a large kindred with myotonic dystrophy. Quantitative assessment and relation to size of CTG repeat expansion. JAMA. 1995 Sep 13; 274(10):813-9. PMID: 7650805.
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    208. Krahe R, Ashizawa T, Abbruzzese C, Roeder E, Carango P, Giacanelli M, Funanage VL, Siciliano MJ. Effect of myotonic dystrophy trinucleotide repeat expansion on DMPK transcription and processing. Genomics. 1995 Jul 01; 28(1):1-14. PMID: 7590731.
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    209. Jankovic J, Beach J, Ashizawa T. Emotional and functional impact of DNA testing on patients with symptoms of Huntington's disease. J Med Genet. 1995 Jul; 32(7):516-8. PMID: 7562962.
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    210. Krahe R, Eckhart M, Ogunniyi AO, Osuntokun BO, Siciliano MJ, Ashizawa T. De novo myotonic dystrophy mutation in a Nigerian kindred. Am J Hum Genet. 1995 May; 56(5):1067-74. PMID: 7726160.
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    211. Monckton DG, Wong LJ, Ashizawa T, Caskey CT. Somatic mosaicism, germline expansions, germline reversions and intergenerational reductions in myotonic dystrophy males: small pool PCR analyses. Hum Mol Genet. 1995 Jan; 4(1):1-8. PMID: 7711720.
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    212. Jankovic J, Ashizawa T. Tourettism associated with Huntington's disease. Mov Disord. 1995 Jan; 10(1):103-5. PMID: 7885343.
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    213. Wong LJ, Ashizawa T, Monckton DG, Caskey CT, Richards CS. Somatic heterogeneity of the CTG repeat in myotonic dystrophy is age and size dependent. Am J Hum Genet. 1995 Jan; 56(1):114-22. PMID: 7825566.
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    214. Jinnai K, Ashizawa T, Atassi MZ. Analysis of exposed regions on the main extracellular domain of mouse acetylcholine receptor alpha subunit in live muscle cells by binding profiles of antipeptide antibodies. J Protein Chem. 1994 Nov; 13(8):715-22. PMID: 7710661.
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    215. Ashizawa T, Wong LJ, Richards CS, Caskey CT, Jankovic J. CAG repeat size and clinical presentation in Huntington's disease. Neurology. 1994 Jun; 44(6):1137-43. PMID: 8208412.
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    216. Ashizawa T, Anvret M, Baiget M, Barceló JM, Brunner H, Cobo AM, Dallapiccola B, Fenwick RG, Grandell U, Harley H, et al. Characteristics of intergenerational contractions of the CTG repeat in myotonic dystrophy. Am J Hum Genet. 1994 Mar; 54(3):414-23. PMID: 8116611.
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    217. Atassi MZ, Mulac-Jericevic B, Ashizawa T. Mapping of the polypeptide chain organization of the main extracellular domain of the alpha-subunit in membrane-bound acetylcholine receptor by antipeptide antibodies spanning the entire domain. Adv Exp Med Biol. 1994; 347:221-8. PMID: 7526636.
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    218. Ashizawa T, Dunne PW, Ward PA, Seltzer WK, Richards CS. Effects of the sex of myotonic dystrophy patients on the unstable triplet repeat in their affected offspring. Neurology. 1994 Jan; 44(1):120-2. PMID: 8290046.
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    219. Ashizawa T, Dubel JR, Harati Y. Somatic instability of CTG repeat in myotonic dystrophy. Neurology. 1993 Dec; 43(12):2674-8. PMID: 8255475.
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    220. Fu YH, Friedman DL, Richards S, Pearlman JA, Gibbs RA, Pizzuti A, Ashizawa T, Perryman MB, Scarlato G, Fenwick RG, et al. Decreased expression of myotonin-protein kinase messenger RNA and protein in adult form of myotonic dystrophy. Science. 1993 Apr 09; 260(5105):235-8. PMID: 8469976.
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    221. Ashizawa T, Ruan KH, Jinnai K, Atassi MZ. Profile of the regions on the alpha-chain of human acetylcholine receptor recognized by autoantibodies in myasthenia gravis. Mol Immunol. 1992 Dec; 29(12):1507-14. PMID: 1280762.
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    222. Ashizawa T, Dunne CJ, Dubel JR, Perryman MB, Epstein HF, Boerwinkle E, Hejtmancik JF. Anticipation in myotonic dystrophy. I. Statistical verification based on clinical and haplotype findings. Neurology. 1992 Oct; 42(10):1871-7. PMID: 1407565.
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    223. Dunne PW, Wang SW, Ashizawa T, Perryman MB, Epstein HF. cDNA surveying of specific tissue expression of human chromosome 19 sequences. Genomics. 1992 Oct; 14(2):263-9. PMID: 1427842.
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    224. Ashizawa T, Dubel JR, Dunne PW, Dunne CJ, Fu YH, Pizzuti A, Caskey CT, Boerwinkle E, Perryman MB, Epstein HF, et al. Anticipation in myotonic dystrophy. II. Complex relationships between clinical findings and structure of the GCT repeat. Neurology. 1992 Oct; 42(10):1877-83. PMID: 1407566.
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    225. Dubel JR, Armstrong RM, Perryman MB, Epstein HF, Ashizawa T. Phenotypic expression of the myotonic dystrophy gene in monozygotic twins. Neurology. 1992 Sep; 42(9):1815-7. PMID: 1513473.
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    226. Atassi MZ, Ruan KH, Jinnai K, Oshima M, Ashizawa T. Epitope-specific suppression of antibody response in experimental autoimmune myasthenia gravis by a monomethoxypolyethylene glycol conjugate of a myasthenogenic synthetic peptide. Proc Natl Acad Sci U S A. 1992 Jul 01; 89(13):5852-6. PMID: 1378618.
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    227. Buxton J, Shelbourne P, Davies J, Jones C, Perryman MB, Ashizawa T, Butler R, Brook D, Shaw D, de Jong P, et al. Characterization of a YAC and cosmid contig containing markers tightly linked to the myotonic dystrophy locus on chromosome 19. Genomics. 1992 Jul; 13(3):526-31. PMID: 1639381.
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    228. Fu YH, Pizzuti A, Fenwick RG, King J, Rajnarayan S, Dunne PW, Dubel J, Nasser GA, Ashizawa T, de Jong P, et al. An unstable triplet repeat in a gene related to myotonic muscular dystrophy. Science. 1992 Mar 06; 255(5049):1256-8. PMID: 1546326.
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    229. Koyama H, Hohdatsu T, Satake M, Kobayashi M, Ashizawa T, Sugimoto K, Yoshikawa H, Okada K, Yoshikawa T, Saito H. Properties of nine continuous B-cell lines established from enzootic bovine leukosis tumors. Zentralbl Veterinarmed B. 1992 Feb; 39(1):32-8. PMID: 1580106.
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    230. Rolak LA, Rutecki P, Ashizawa T, Harati Y. Clinical features of Todd's post-epileptic paralysis. J Neurol Neurosurg Psychiatry. 1992 Jan; 55(1):63-4. PMID: 1548500.
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    231. Ashizawa T, Hejtmancik JF, Liu J, Perryman MB, Epstein HF, Koch DD. Diagnostic value of ophthalmologic findings in myotonic dystrophy: comparison with risks calculated by haplotype analysis of closely linked restriction fragment length polymorphisms. Am J Med Genet. 1992 Jan 01; 42(1):55-60. PMID: 1364051.
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    232. Akinaga S, Ashizawa T, Gomi K, Ohno H, Morimoto M, Murakata C, Okabe M. Antitumor effect of KT6124, a novel derivative of protein kinase inhibitor K-252a, and its mechanism of action. Cancer Chemother Pharmacol. 1992; 29(4):266-72. PMID: 1537071.
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    233. Ashizawa T, Epstein HF. Ethnic distribution of myotonic dystrophy gene. Lancet. 1991 Sep 07; 338(8767):642-3. PMID: 1679186.
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    234. Ashizawa T, Oshima M, Ruan KH, Atassi MZ. Autoimmune recognition profile of the alpha chain of human acetylcholine receptor in myasthenia gravis. Adv Exp Med Biol. 1991; 303:255-61. PMID: 1805569.
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    235. Oshima M, Ashizawa T, Pollack MS, Atassi MZ. Autoimmune T cell recognition of human acetylcholine receptor: the sites of T cell recognition in myasthenia gravis on the extracellular part of the alpha subunit. Eur J Immunol. 1990 Dec; 20(12):2563-9. PMID: 2269324.
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    236. Perryman MB, Hejtmancik JF, Ashizawa T, Armstrong R, Lin SC, Roberts R, Epstein HF. NcoI and TaqI RFLPs for human M creatine kinase (CKM) Nucleic Acids Res. 1988 Sep 12; 16(17):8744. PMID: 2901731.
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    237. Stewart SS, Ashizawa T, Dudley AW, Goldberg JW, Lidsky MD. Cerebral vasculitis in relapsing polychondritis. Neurology. 1988 Jan; 38(1):150-2. PMID: 3336448.
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    238. Ashizawa T, Rolak LA, Hines M. Spastic pure motor monoparesis. Ann Neurol. 1986 Nov; 20(5):638-41. PMID: 3789679.
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    239. Ashizawa T. False positive anti-acetylcholine receptor antibodies in motorneurone disease. Lancet. 1986 May 31; 1(8492):1272. PMID: 2872411.
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    240. Levy JD, Cottingham KL, Campbell RJ, Moore GK, Gyorkey F, Ashizawa T, Goldman AM. Progressive multifocal leukoencephalopathy and magnetic resonance imaging. Ann Neurol. 1986 Apr; 19(4):399-401. PMID: 3707094.
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    241. Ashizawa T, Appel SH. Complement-dependent lysis of cultured rat myotubes by myasthenic immunoglobulins. Neurology. 1985 Dec; 35(12):1748-53. PMID: 4069366.
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    242. Rolak LA, Ashizawa T. The hot bath test in multiple sclerosis: comparison with visual evoked responses and oligoclonal bands. Acta Neurol Scand. 1985 Jul; 72(1):65-7. PMID: 4050319.
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    243. Diaz-Arrastia R, Ashizawa T, Appel SH. Endogenous inhibitor of ligand binding to the muscarinic acetylcholine receptor. J Neurochem. 1985 Feb; 44(2):622-8. PMID: 3917491.
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    244. Ashizawa T, Appel SH. Immunopathologic events at the endplate in myasthenia gravis. Springer Semin Immunopathol. 1985; 8(3):177-96. PMID: 2413561.
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    245. Ashizawa T, Kido C, Ariyoshi Y, Kondo K. [Significance of time-lapse changes in gallium-67 citrate accumulation in the diagnosis of hepatoma]. Kaku Igaku. 1983 Dec; 20(10):1449-58. PMID: 6328069.
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    246. Rolak LA, Ashizawa T. The hot bath test. JAMA. 1983 Dec 23-30; 250(24):3281-2. PMID: 6645021.
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    247. Takagi H, Morimoto T, Yasue M, Ochiai E, Yamada E, Ashizawa T, Kido C. Ligation and catheterization of the hepatic artery for palliative treatment of malignant hepatic tumors. J Surg Oncol. 1983 Aug; 23(4):219-22. PMID: 6192288.
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    248. Ashizawa T, Butler IJ, Harati Y, Roongta SM. A dominantly inherited syndrome with continuous motor neuron discharges. Ann Neurol. 1983 Mar; 13(3):285-90. PMID: 6847141.
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    249. Hara S, Kido C, Satoh S, Ashizawa T. [CT images of diffuse hepatic disease]. Rinsho Hoshasen. 1982 Dec; 27(13):1411-6. PMID: 7166854.
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    250. Appel SH, Blosser JC, McManaman JL, Ashizawa T. Acetylcholine receptor turnover in myasthenia gravis. Am J Physiol. 1982 Jul; 243(1):E31-6. PMID: 7091363.
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    251. Ashizawa T, Elias SB, Appel SH. Interaction of myasthenic immunoglobulins and cholinergic agonists on acetylcholine receptors of rat myotubes. Ann Neurol. 1982 Jan; 11(1):22-7. PMID: 6277235.
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    252. Appel SH, Blosser JC, McManaman JL, Ashizawa T, Elias SB. The effects of carbamylcholine, calcium, and cyclic nucleotides on acetylcholine receptor synthesis in cultured myotubes. Ann N Y Acad Sci. 1981; 377:189-97. PMID: 6951472.
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    253. Ashizawa T, Patten BM, Jankovic J. Meige's syndrome. South Med J. 1980 Jul; 73(7):863-6. PMID: 7384844.
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    254. Miyagawa N, Ashizawa T, Kashiba S, Miyagawa S, Fujio H. Antigenic determinants of hen egg-white lysozyme in delayed hypersensitivity. I. Macrophage migration inhibition activities of lysozyme fragments. Biken J. 1975 Dec; 18(4):215-28. PMID: 56171.
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    255. Miyagawa N, Ashizawa T, Kashiba S, Miyagawa S, Fujio H. Antigenic determinants of hen egg-white lysozyme in delayed hypersensitivity. II. Antigenicity and immunogenicity of the N- and C-terminal peptide. Biken J. 1975 Dec; 18(4):229-47. PMID: 56172.
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