TitleAssociate Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Ophthalmology
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    Other Positions
    TitleAssociate Professor
    InstitutionBaylor College of Medicine
    DepartmentDepartment of Neuroscience

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    K08EY021479     (FRANKFORT, BENJAMIN J)Aug 1, 2011 - Jul 31, 2016
    Role: Principal Investigator

    R01EY025601     (FRANKFORT, BENJAMIN J)Aug 1, 2015 - Jul 31, 2024
    Brain and eye pressure-induced optic nerve and retinal degeneration
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Ford RL, Frankfort BJ, Fleischman D. Cerebrospinal fluid and ophthalmic disease. Curr Opin Ophthalmol. 2022 Mar 01; 33(2):73-79. PMID: 34698673.
      Citations:    Fields:    Translation:Humans
    2. Ramamoorthy P, Alexander NL, Frankfort BJ. Abnormal perception of pattern-induced flicker colors in subjects with glaucoma. J Vis. 2022 02 01; 22(2):5. PMID: 35133432.
      Citations:    Fields:    Translation:Humans
    3. Zafar S, Staggers KA, Gao J, Liu Y, Patel PJ, Foster PJ, Frankfort BJ, Abramoff M, Minard CG, Warwick A, Khawaja AP, Channa R. Evaluation of retinal nerve fibre layer thickness as a possible measure of diabetic retinal neurodegeneration in the EPIC-Norfolk Eye Study. Br J Ophthalmol. 2021 Dec 24. PMID: 34952836.
      Citations:    Fields:    
    4. Channa R, Lee K, Staggers KA, Mehta N, Zafar S, Gao J, Frankfort BJ, Chua SYL, Khawaja AP, Foster PJ, Patel PJ, Minard CG, Amos C, Abramoff MD. Detecting retinal neurodegeneration in people with diabetes: Findings from the UK Biobank. PLoS One. 2021; 16(9):e0257836. PMID: 34587216.
      Citations:    Fields:    Translation:HumansCells
    5. Biggerstaff KS, White DL, Frankfort BJ, Richardson P, Orengo-Nania S, Garcia J, Chiao EY, Kramer JR. Gout and open-angle glaucoma risk in a veteran population. Graefes Arch Clin Exp Ophthalmol. 2021 Nov; 259(11):3371-3379. PMID: 34272610.
      Citations: 1     Fields:    Translation:Humans
    6. Park YH, Snook JD, Zhuang I, Shen G, Frankfort BJ. Optimized culture of retinal ganglion cells and amacrine cells from adult mice. PLoS One. 2020; 15(12):e0242426. PMID: 33284815.
      Citations: 2     Fields:    Translation:AnimalsCells
    7. Chen H, McMillin JC, Frankfort BJ, Al-Mohtaseb Z. Reticular Epithelial Edema: An Uncommon Side Effect of ROCK/NET Inhibitor Netarsudil. J Glaucoma. 2020 11; 29(11):e124-e126. PMID: 32826765.
      Citations: 2     Fields:    Translation:Humans
    8. Tao X, Sigireddi RR, Westenskow PD, Channa R, Frankfort BJ. Single transient intraocular pressure elevations cause prolonged retinal ganglion cell dysfunction and retinal capillary abnormalities in mice. Exp Eye Res. 2020 12; 201:108296. PMID: 33039455.
      Citations: 1     Fields:    Translation:AnimalsCells
    9. Tao X, Sabharwal J, Wu SM, Frankfort BJ. Intraocular Pressure Elevation Compromises Retinal Ganglion Cell Light Adaptation. Invest Ophthalmol Vis Sci. 2020 10 01; 61(12):15. PMID: 33064129.
      Citations: 4     Fields:    Translation:AnimalsCells
    10. Shen G, Link SS, Tao X, Frankfort BJ. Modeling a potential SANS countermeasure by experimental manipulation of the translaminar pressure difference in mice. NPJ Microgravity. 2020; 6:19. PMID: 32821777.
    11. Shen G, Link S, Kumar S, Nusbaum DM, Tse DY, Fu Y, Wu SM, Frankfort BJ. Author Correction: Characterization of Retinal Ganglion Cell and Optic Nerve Phenotypes Caused by Sustained Intracranial Pressure Elevation in Mice. Sci Rep. 2019 Oct 08; 9(1):14727. PMID: 31591458.
      Citations:    Fields:    
    12. Zafar S, Sachdeva M, Frankfort BJ, Channa R. Retinal Neurodegeneration as an Early Manifestation of Diabetic Eye Disease and Potential Neuroprotective Therapies. Curr Diab Rep. 2019 02 26; 19(4):17. PMID: 30806815.
      Citations: 9     Fields:    Translation:HumansAnimals
    13. Park YH, Snook JD, Ostrin EJ, Kim S, Chen R, Frankfort BJ. Transcriptomic profiles of retinal ganglion cells are defined by the magnitude of intraocular pressure elevation in adult mice. Sci Rep. 2019 02 22; 9(1):2594. PMID: 30796289.
      Citations: 10     Fields:    Translation:AnimalsCells
    14. Tao X, Sabharwal J, Seilheimer RL, Wu SM, Frankfort BJ. Mild Intraocular Pressure Elevation in Mice Reveals Distinct Retinal Ganglion Cell Functional Thresholds and Pressure-Dependent Properties. J Neurosci. 2019 03 06; 39(10):1881-1891. PMID: 30622167.
      Citations: 11     Fields:    Translation:AnimalsCells
    15. Shen G, Link S, Kumar S, Nusbaum DM, Tse DY, Fu Y, Wu SM, Frankfort BJ. Characterization of Retinal Ganglion Cell and Optic Nerve Phenotypes Caused by Sustained Intracranial Pressure Elevation in Mice. Sci Rep. 2018 02 12; 8(1):2856. PMID: 29434244.
      Citations: 6     Fields:    Translation:AnimalsCells
    16. Sigireddi RR, Frankfort BJ. Neuroprotection in Glaucoma. Int Ophthalmol Clin. 2018; 58(3):51-67. PMID: 29870410.
      Citations:    Fields:    Translation:Humans
    17. Mayer RR, Frankfort BJ, Strickland BA, Debnam JM, McCutcheon IE, Groves MD, Weinberg JS. Leptomeningeal metastases presenting exclusively with ocular disturbance in 34 patients: A tertiary care cancer hospital experience. J Clin Neurosci. 2017 May; 39:151-154. PMID: 28215459.
      Citations: 2     Fields:    Translation:Humans
    18. Biggerstaff KS, Vincent RD, Lin AP, Orengo-Nania S, Frankfort BJ. Trabeculectomy Outcomes by Supervised Trainees in a Veterans Affairs Medical Center. J Glaucoma. 2016 08; 25(8):669-73. PMID: 26950572.
      Citations: 2     Fields:    Translation:Humans
    19. van der Heijden ME, Shah P, Cowan CS, Yang Z, Wu SM, Frankfort BJ. Effects of Chronic and Acute Intraocular Pressure Elevation on Scotopic and Photopic Contrast Sensitivity in Mice. Invest Ophthalmol Vis Sci. 2016 06 01; 57(7):3077-87. PMID: 27286365.
      Citations: 9     Fields:    Translation:AnimalsCells
    20. Jeang LJ, Chang PT, Frankfort BJ. Rapidly progressing glaucoma associated with monoclonal gammopathy. J Glaucoma. 2015 Jun-Jul; 24(5):e139-41. PMID: 24844541.
      Citations: 1     Fields:    Translation:Humans
    21. Nusbaum DM, Wu SM, Frankfort BJ. Elevated intracranial pressure causes optic nerve and retinal ganglion cell degeneration in mice. Exp Eye Res. 2015 Jul; 136:38-44. PMID: 25912998.
      Citations: 16     Fields:    Translation:AnimalsCells
    22. Pang JJ, Frankfort BJ, Gross RL, Wu SM. Elevated intraocular pressure decreases response sensitivity of inner retinal neurons in experimental glaucoma mice. Proc Natl Acad Sci U S A. 2015 Feb 24; 112(8):2593-8. PMID: 25675503.
      Citations: 49     Fields:    Translation:HumansAnimalsCells
    23. Khan AK, Tse DY, van der Heijden ME, Shah P, Nusbaum DM, Yang Z, Wu SM, Frankfort BJ. Prolonged elevation of intraocular pressure results in retinal ganglion cell loss and abnormal retinal function in mice. Exp Eye Res. 2015 Jan; 130:29-37. PMID: 25450059.
      Citations: 19     Fields:    Translation:AnimalsCells
    24. Butler MR, Prospero Ponce CM, Weinstock YE, Orengo-Nania S, Chevez-Barrios P, Frankfort BJ. Topical silver nanoparticles result in improved bleb function by increasing filtration and reducing fibrosis in a rabbit model of filtration surgery. Invest Ophthalmol Vis Sci. 2013 Jul 24; 54(7):4982-90. PMID: 23766475.
      Citations: 5     Fields:    Translation:Animals
    25. Frankfort BJ, Khan AK, Tse DY, Chung I, Pang JJ, Yang Z, Gross RL, Wu SM. Elevated intraocular pressure causes inner retinal dysfunction before cell loss in a mouse model of experimental glaucoma. Invest Ophthalmol Vis Sci. 2013 Jan 28; 54(1):762-70. PMID: 23221072.
      Citations: 68     Fields:    Translation:AnimalsCells
    26. Lee BS, Frankfort BJ, Eberhart CG, Weinberg RS. Diagnosis of intravascular lymphoma by a novel biopsy site. Ophthalmology. 2011 Mar; 118(3):586-90. PMID: 21035865.
      Citations: 1     Fields:    Translation:Humans
    27. Pepple KL, Atkins M, Venken K, Wellnitz K, Harding M, Frankfort B, Mardon G. Two-step selection of a single R8 photoreceptor: a bistable loop between senseless and rough locks in R8 fate. Development. 2008 Dec; 135(24):4071-9. PMID: 19004852.
      Citations: 32     Fields:    Translation:AnimalsCells
    28. Frankfort BJ, Garibaldi DC. Periocular cutaneous toxicity and cicatricial ectropion: a potential class effect of antineoplastic agents that inhibit EGFR signaling. Ophthalmic Plast Reconstr Surg. 2007 Nov-Dec; 23(6):496-7. PMID: 18030130.
      Citations: 6     Fields:    Translation:Humans
    29. Pepple KL, Anderson AE, Frankfort BJ, Mardon G. A genetic screen in Drosophila for genes interacting with senseless during neuronal development identifies the importin moleskin. Genetics. 2007 Jan; 175(1):125-41. PMID: 17110483.
      Citations: 11     Fields:    Translation:AnimalsCells
    30. Domingos PM, Brown S, Barrio R, Ratnakumar K, Frankfort BJ, Mardon G, Steller H, Mollereau B. Regulation of R7 and R8 differentiation by the spalt genes. Dev Biol. 2004 Sep 01; 273(1):121-33. PMID: 15302602.
      Citations: 32     Fields:    Translation:AnimalsCells
    31. Frankfort BJ, Pepple KL, Mamlouk M, Rose MF, Mardon G. Senseless is required for pupal retinal development in Drosophila. Genesis. 2004 Apr; 38(4):182-94. PMID: 15083519.
      Citations: 8     Fields:    Translation:AnimalsCells
    32. Frankfort BJ, Mardon G. Senseless represses nuclear transduction of Egfr pathway activation. Development. 2004 Feb; 131(3):563-70. PMID: 14711872.
      Citations: 12     Fields:    Translation:AnimalsCells
    33. Rayapureddi JP, Kattamuri C, Steinmetz BD, Frankfort BJ, Ostrin EJ, Mardon G, Hegde RS. Eyes absent represents a class of protein tyrosine phosphatases. Nature. 2003 Nov 20; 426(6964):295-8. PMID: 14628052.
      Citations: 96     Fields:    Translation:AnimalsCells
    34. Frankfort BJ, Mardon G. R8 development in the Drosophila eye: a paradigm for neural selection and differentiation. Development. 2002 Mar; 129(6):1295-306. PMID: 11880339.
      Citations: 59     Fields:    Translation:AnimalsCells
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